| Selective small-molecule inhibition of an RNA structural element JA Howe, H Wang, TO Fischmann, CJ Balibar, L Xiao, AM Galgoci, ... Nature 526 (7575), 672-677, 2015 | 380 | 2015 |
| Total synthesis of ingenol A Nickel, T Maruyama, H Tang, PD Murphy, B Greene, N Yusuff, JL Wood Journal of the American Chemical Society 126 (50), 16300-16301, 2004 | 143 | 2004 |
| Ligands for Palladium‐Catalyzed Cross‐Couplings of Alkyl Halides: Use of an Alkyldiaminophosphane Expands the Scope of the Stille Reaction H Tang, K Menzel, GC Fu Angewandte Chemie International Edition 42 (41), 5079-5082, 2003 | 117 | 2003 |
| Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch JA Howe, L Xiao, TO Fischmann, H Wang, H Tang, A Villafania, R Zhang, ... RNA biology 13 (10), 946-954, 2016 | 68 | 2016 |
| Progress toward the total synthesis of ingenol: Construction of the complete carbocyclic skeleton H Tang, N Yusuff, JL Wood Organic Letters 3 (10), 1563-1566, 2001 | 64 | 2001 |
| Discovery of selective small molecule ROMK inhibitors as potential new mechanism diuretics H Tang, SP Walsh, Y Yan, RK de Jesus, A Shahripour, N Teumelsan, ... ACS Medicinal Chemistry Letters 3 (5), 367-372, 2012 | 48 | 2012 |
| Pharmacologic inhibition of the renal outer medullary potassium channel causes diuresis and natriuresis in the absence of kaliuresis ML Garcia, BT Priest, M Alonso-Galicia, X Zhou, JP Felix, RM Brochu, ... Journal of Pharmacology and Experimental Therapeutics 348 (1), 153-164, 2014 | 36 | 2014 |
| Discovery of MK-7145, an oral small molecule ROMK inhibitor for the treatment of hypertension and heart failure H Tang, Y Zhu, N Teumelsan, SP Walsh, A Shahripour, BT Priest, ... ACS Medicinal Chemistry Letters 7 (7), 697-701, 2016 | 31 | 2016 |
| Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one H Tang, RK de Jesus, SP Walsh, Y Zhu, Y Yan, BT Priest, AM Swensen, ... Bioorganic & medicinal chemistry letters 23 (21), 5829-5832, 2013 | 29 | 2013 |
| Design and synthesis of a new class of malonyl-CoA decarboxylase inhibitors with anti-obesity and anti-diabetic activities H Tang, Y Yan, Z Feng, RK de Jesus, L Yang, DA Levorse, KA Owens, ... Bioorganic & medicinal chemistry letters 20 (20), 6088-6092, 2010 | 28 | 2010 |
| Inhibitors of the renal outer medullary potassium channel A Pasternak, A Shahripour, H Tang, NH Teumelsan, L Yang, Y Zhu, ... US Patent 8,673,920, 2014 | 25 | 2014 |
| The inwardly rectifying potassium channel Kir1. 1: development of functional assays to identify and characterize channel inhibitors JP Felix, BT Priest, K Solly, T Bailey, RM Brochu, CJ Liu, MG Kohler, ... Assay and drug development technologies 10 (5), 417-431, 2012 | 22 | 2012 |
| The renal outer medullary potassium channel inhibitor, MK-7145, lowers blood pressure, and manifests features of Bartter’s syndrome Type II phenotype C Hampton, X Zhou, BT Priest, LY Pai, JP Felix, B Thomas-Fowlkes, J Liu, ... Journal of Pharmacology and Experimental Therapeutics 359 (1), 194-206, 2016 | 17 | 2016 |
| Inhibitors of the renal outer medullary potassium channel FX Ding, S Dong, J Frie, X Gu, J Jiang, A Pasternak, H Tang, Z Wu, Y Yu, ... US Patent 8,952,166, 2015 | 17 | 2015 |
| Inhibitors of the renal outer medullary potassium channel A Pasternak, T Blizzard, H Chobanian, R De Jesus, FX Ding, S Dong, ... US Patent 9,062,070, 2015 | 16 | 2015 |
| Inhibitors of the renal outer medullary potassium channel H Tang, B Pio, J Jiang, A Pasternak, S Dong, IIRD Ferguson, ZZ Guo, ... US Patent 9,751,881, 2017 | 14 | 2017 |
| Discovery of a potent and selective ROMK inhibitor with pharmacokinetic properties suitable for preclinical evaluation SP Walsh, A Shahripour, H Tang, N Teumelsan, J Frie, Y Zhu, BT Priest, ... ACS Medicinal Chemistry Letters 6 (7), 747-752, 2015 | 14 | 2015 |
| Inhibitors of the renal outer medullary potassium channel H Tang, B Pio, N Teumelsan, A Pasternak, R DeJesus US Patent 8,999,990, 2015 | 12 | 2015 |
| Improvement of hERG-ROMK index of spirocyclic ROMK inhibitors through scaffold optimization and incorporation of novel pharmacophores S Dong, K VanGelder, ZC Shi, Y Yu, Z Wu, R Ferguson, ZZ Guo, H Tang, ... Bioorganic & Medicinal Chemistry Letters 27 (11), 2559-2566, 2017 | 11 | 2017 |
| Can we make small molecules lean? Optimization of a highly lipophilic TarO inhibitor M Mandal, Z Tan, C Madsen-Duggan, AV Buevich, JP Caldwell, ... Journal of Medicinal Chemistry 60 (9), 3851-3865, 2017 | 11 | 2017 |
