| Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A D Jiang, Y Zhao, X Wang, J Fan, J Heng, X Liu, W Feng, X Kang, B Huang, ... Proceedings of the National Academy of Sciences 110 (36), 14664-14669, 2013 | 204 | 2013 |
| Structure of the APPL1 BAR‐PH domain and characterization of its interaction with Rab5 G Zhu, J Chen, J Liu, JS Brunzelle, B Huang, N Wakeham, S Terzyan, X Li, ... The EMBO journal 26 (14), 3484-3493, 2007 | 149 | 2007 |
| BH 3‐in‐groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranes Z Zhang, S Subramaniam, J Kale, C Liao, B Huang, H Brahmbhatt, ... The EMBO journal 35 (2), 208-236, 2016 | 106 | 2016 |
| Crystal structure of cytotoxin protein suilysin from Streptococcus suis L Xu, B Huang, H Du, XC Zhang, J Xu, X Li, Z Rao Protein & Cell 1 (1), 96-105, 2010 | 93 | 2010 |
| After embedding in membranes antiapoptotic Bcl-XL protein binds both Bcl-2 homology region 3 and helix 1 of proapoptotic Bax protein to inhibit apoptotic mitochondrial … J Ding, BHM Mooers, Z Zhang, J Kale, D Falcone, J McNichol, B Huang, ... Journal of Biological Chemistry 289 (17), 11873-11896, 2014 | 84 | 2014 |
| Crystal structure of 1, 3Gal43A, an exo-β-1, 3-galactanase from Clostridium thermocellum D Jiang, J Fan, X Wang, Y Zhao, B Huang, J Liu, XC Zhang Journal of structural biology 180 (3), 447-457, 2012 | 45 | 2012 |
| An efficient strategy for high throughput screening of recombinant integral membrane protein expression and stability J Fan, J Heng, S Dai, N Shaw, B Zhou, B Huang, Z He, Y Wang, T Jiang, ... Protein expression and purification 78 (1), 6-13, 2011 | 43 | 2011 |
| Structure, gating, and pharmacology of human CaV3.3 channel L He, Z Yu, Z Geng, Z Huang, C Zhang, Y Dong, Y Gao, Y Wang, Q Chen, ... Nature communications 13 (1), 2084, 2022 | 39 | 2022 |
| A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors L Yan, Y Huang, J Ge, Z Liu, P Lu, B Huang, S Gao, J Wang, L Tan, S Ye, ... Cell 185 (23), 4347-4360. e17, 2022 | 34 | 2022 |
| Structure of human NaV1.6 channel reveals Na+ selectivity and pore blockade by 4,9-anhydro-tetrodotoxin Y Li, T Yuan, B Huang, F Zhou, C Peng, X Li, Y Qiu, B Yang, Y Zhao, ... Nature Communications 14 (1), 1030, 2023 | 24 | 2023 |
| A pocket-based 3D molecule generative model fueled by experimental electron density L Wang, R Bai, X Shi, W Zhang, Y Cui, X Wang, C Wang, H Chang, ... Scientific reports 12 (1), 15100, 2022 | 21 | 2022 |
| Generation of 3D molecules in pockets via a language model W Feng, L Wang, Z Lin, Y Zhu, H Wang, J Dong, R Bai, H Wang, J Zhou, ... Nature Machine Intelligence 6 (1), 62-73, 2024 | 19 | 2024 |
| Observing noncovalent interactions in experimental electron density for macromolecular systems: a novel perspective for protein–ligand interaction research K Ding, S Yin, Z Li, S Jiang, Y Yang, W Zhou, Y Zhang, B Huang Journal of Chemical Information and Modeling 62 (7), 1734-1743, 2022 | 18 | 2022 |
| Transport and inhibition mechanisms of human VMAT2 D Wu, Q Chen, Z Yu, B Huang, J Zhao, Y Wang, J Su, F Zhou, R Yan, N Li, ... Nature 626 (7998), 427-434, 2024 | 16 | 2024 |
| Functional study on GTP hydrolysis by the GTP-binding protein from Sulfolobus solfataricus, a member of the HflX family B Huang, H Wu, N Hao, F Blombach, J Van der Oost, X Li, XC Zhang, ... The journal of biochemistry 148 (1), 103-113, 2010 | 15 | 2010 |
| Predicting memapsin 2 (β‐secretase) hydrolytic activity X Li, H Bo, XC Zhang, JA Hartsuck, J Tang Protein Science 19 (11), 2175-2185, 2010 | 13 | 2010 |
| N-type fast inactivation of a eukaryotic voltage-gated sodium channel J Zhang, Y Shi, J Fan, H Chen, Z Xia, B Huang, J Jiang, J Gong, Z Huang, ... Nature Communications 13 (1), 2713, 2022 | 12 | 2022 |
| Structural basis of human Slo2. 2 channel gating and modulation J Zhang, S Liu, J Fan, R Yan, B Huang, F Zhou, T Yuan, J Gong, Z Huang, ... Cell reports 42 (8), 2023 | 9 | 2023 |
| Structural insight into the allosteric inhibition of human sodium-calcium exchanger NCX1 by XIP and SEA0400 Y Dong, Z Yu, Y Li, B Huang, Q Bai, Y Gao, Q Chen, N Li, L He, Y Zhao The EMBO Journal 43 (1), 14-31, 2024 | 8 | 2024 |
| Bridging the gap between chemical reaction pretraining and conditional molecule generation with a unified model B Qiang, Y Zhou, Y Ding, N Liu, S Song, L Zhang, B Huang, Z Liu Nature Machine Intelligence 5 (12), 1476-1485, 2023 | 7 | 2023 |
