关注
Jonas Jutzi
Jonas Jutzi
Instructor in Medicine, Harvard Medical School
在 bwh.harvard.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Oncogenic JAK2V617F causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms
A Prestipino, AJ Emhardt, K Aumann, D O’Sullivan, SP Gorantla, ...
Science translational medicine 10 (429), eaam7729, 2018
2212018
Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both
S Koschmieder, TI Mughal, HC Hasselbalch, G Barosi, P Valent, ...
Leukemia 30 (5), 1018-1024, 2016
1622016
LSD1 inhibition prolongs survival in mouse models of MPN by selectively targeting the disease clone
JS Jutzi, M Kleppe, J Dias, HF Staehle, K Shank, J Teruya-Feldstein, ...
Hemasphere 2 (3), e54, 2018
912018
MPN patients harbor recurrent truncating mutations in transcription factor NF-E2
JS Jutzi, R Bogeska, G Nikoloski, CA Schmid, TS Seeger, F Stegelmann, ...
Journal of Experimental Medicine 210 (5), 1003-1019, 2013
882013
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
KB Kaufmann, A Gründer, T Hadlich, J Wehrle, M Gothwal, R Bogeska, ...
Journal of Experimental Medicine 209 (1), 35-50, 2012
872012
BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cells
S Afreen, S Bohler, A Müller, EM Demmerath, JM Weiss, JS Jutzi, ...
Cell Death & Disease 11 (1), 8, 2020
482020
Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms
JC Peeken, JS Jutzi, J Wehrle, C Koellerer, HF Staehle, H Becker, ...
Blood, The Journal of the American Society of Hematology 131 (18), 2065-2073, 2018
412018
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations
JS Jutzi, T Basu, M Pellmann, S Kaiser, D Steinemann, MA Sanders, ...
Blood, The Journal of the American Society of Hematology 133 (16), 1766-1777, 2019
362019
Remodeling the bone marrow microenvironment–a proposal for targeting pro-inflammatory contributors in MPN
JS Jutzi, A Mullally
Frontiers in Immunology 11, 2093, 2020
242020
The hen or the egg: inflammatory aspects of murine MPN models
JS Jutzi, HL Pahl
Mediators of Inflammation 2015 (1), 101987, 2015
162015
Whole-genome CRISPR screening identifies N-glycosylation as a genetic and therapeutic vulnerability in CALR-mutant MPNs
JS Jutzi, AE Marneth, M Ciboddo, A Guerra-Moreno, MJ Jiménez-Santos, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1291-1304, 2022
122022
Enhanced expression of the sphingosine-1-phosphate-receptor-3 causes acute myelogenous leukemia in mice
S Vorbach, A Gründer, F Zhou, C Koellerer, JS Jutzi, M Simoni, L Riccetti, ...
Leukemia 34 (3), 721-734, 2020
102020
CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response
JS Jutzi, AE Marneth, MJ Jiménez-Santos, J Hem, A Guerra-Moreno, ...
Leukemia 37 (2), 359-369, 2023
72023
The cross marks the spot: the emerging role of JmjC domain-containing proteins in myeloid malignancies
HF Staehle, HL Pahl, JS Jutzi
Biomolecules 11 (12), 1911, 2021
72021
Method for the diagnosis of myeloid neoplasias and solid tumors
H Pahl, J Jutzi
US Patent 9,695,480, 2017
72017
Jmjd1c is dispensable for healthy adult hematopoiesis and Jak2V617F-driven myeloproliferative disease initiation in mice
HF Staehle, J Heinemann, A Gruender, AM Omlor, HL Pahl, JS Jutzi
Plos one 15 (2), e0228362, 2020
62020
The histone demethylase JMJD2C constitutes a novel NFE2 target gene that is required for the survival of JAK2V617F mutated cells
AM Staehle, JC Peeken, G Vladimirov, ME Hoeness, S Bojtine Kovacs, ...
Leukemia 37 (4), 919-923, 2023
32023
Updated Findings of a Phase II Study of Ruxolitinib Pre-, during-and Post-Hematopoietic Stem Cell Transplantation for Patients with Primary or Secondary Myelofibrosis
GS Hobbs, HT Kim, S O'Connor, MA Schroeder, R Tamari, SA Wall, ...
Blood 142, 2103, 2023
22023
Effectiveness of LSD1 inhibition for the treatment of MPN
JS Jutzi, H Rienhoff, HL Pahl
Haematologica 102, 148-148, 2017
22017
Two to tango! IL-13 and TGF-β drive myelofibrosis
JS Jutzi, A Mullally
Blood, The Journal of the American Society of Hematology 140 (26), 2767-2768, 2022
12022
系统目前无法执行此操作,请稍后再试。
文章 1–20