| MCC950 closes the active conformation of NLRP3 to an inactive state A Tapia-Abellán, D Angosto-Bazarra, H Martínez-Banaclocha, ... Nature chemical biology 15 (6), 560-564, 2019 | 334 | 2019 |
| Development of an acrylate derivative targeting the NLRP3 inflammasome for the treatment of inflammatory bowel disease M Cocco, C Pellegrini, H Martínez-Banaclocha, M Giorgis, E Marini, ... Journal of Medicinal Chemistry 60 (9), 3656-3671, 2017 | 149 | 2017 |
| NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway I Hafner-Bratkovič, P Sušjan, D Lainšček, A Tapia-Abellán, K Cerović, ... Nature communications 9 (1), 5182, 2018 | 127 | 2018 |
| Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation A Tapia-Abellán, D Angosto-Bazarra, C Alarcón-Vila, MC Baños, ... Science advances 7 (38), eabf4468, 2021 | 85 | 2021 |
| Recent insights into the regulatory networks of NLRP3 inflammasome activation ANR Weber, ZA Bittner, S Shankar, X Liu, TH Chang, T Jin, ... Journal of cell science 133 (23), jcs248344, 2020 | 69 | 2020 |
| BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity ZA Bittner, X Liu, M Mateo Tortola, A Tapia-Abellán, S Shankar, ... Journal of Experimental Medicine 218 (11), e20201656, 2021 | 47 | 2021 |
| The peritoneal macrophage inflammatory profile in cirrhosis depends on the alcoholic or hepatitis C viral etiology and is related to ERK phosphorylation A Tapia-Abellán, M Martínez-Esparza, AJ Ruiz-Alcaraz, ... BMC immunology 13, 1-9, 2012 | 31 | 2012 |
| Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization A Baroja-Mazo, V Compan, F Martín-Sánchez, A Tapia-Abellán, I Couillin, ... Scientific reports 9 (1), 5788, 2019 | 29 | 2019 |
| Role of MAP Kinases and PI 3K‐Akt on the cytokine inflammatory profile of peritoneal macrophages from the ascites of cirrhotic patients A Tapia‐Abellán, AJ Ruiz‐Alcaraz, T Hernández‐Caselles, J Such, ... Liver International 33 (4), 552-560, 2013 | 27 | 2013 |
| Peritoneal macrophage priming in cirrhosis is related to ERK phosphorylation and IL-6 secretion. RF Antonio J Ruiz-Alcaraz 1 , María Martínez-Esparza, Rocío Caño, Trinidad ... European Journal of Clinical Investigation 41 (1), 8-15, 2011 | 26 | 2011 |
| A novel CD14high CD16high subset of peritoneal macrophages from cirrhotic patients is associated to an increased response to LPS AJ Ruiz-Alcaraz, A Tapia-Abellán, MD Fernández-Fernández, ... Molecular Immunology 72, 28-36, 2016 | 23 | 2016 |
| Glycoconjugate expression on the cell wall of tps1/tps1 trehalose-deficient Candida albicans strain and implications for its interaction with macrophages M Martínez-Esparza, A Tapia-Abellán, A Vitse-Standaert, ... Glycobiology 21 (6), 796-805, 2011 | 22 | 2011 |
| Isolation of functional mature peritoneal macrophages from healthy humans AJ Ruiz‐Alcaraz, H Martínez‐Banaclocha, P Marín‐Sánchez, ... Immunology and Cell Biology 98 (2), 114-126, 2020 | 16 | 2020 |
| Regulatory role of PI3K-protein kinase B on the release of interleukin-1β in peritoneal macrophages from the ascites of cirrhotic patients A Tapia-Abellán, AJ Ruiz-Alcaraz, G Antón, M Miras-López, R Francés, ... Clinical & Experimental Immunology 178 (3), 525-536, 2014 | 12 | 2014 |
| Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3 ANR Weber, A Tapia-Abellán, X Liu, S Dickhöfer, JI Aróstegui, P Pelegrín, ... Rheumatology 61 (10), e299-e313, 2022 | 11* | 2022 |
| ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux F Martín-Sánchez, V Compan, A Peñín-Franch, A Tapia-Abellán, ... Journal of Cell Biology 222 (8), 2023 | 6 | 2023 |
| Non-decameric NLRP3 forms an MTOC-independent inflammasome M Mateo-Tortola, IV Hochheiser, J Grga, JS Mueller, M Geyer, ... Biorxiv, 2023.07. 07.548075, 2023 | 4 | 2023 |
| Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production C Molina-López, L Hurtado-Navarro, CJ García, D Angosto-Bazarra, ... Nature Communications 15 (1), 1096, 2024 | | 2024 |
| Measuring NLR Oligomerization III: Detection of NLRP3 and NLRC4 Complex by Bioluminescence Resonance Energy Transfer F Martín-Sánchez, A Peñín-Franch, D Angosto-Bazarra, A Tapia-Abellán, ... NLR Proteins: Methods and Protocols, 93-103, 2023 | | 2023 |
| Comment on: Effective ex vivo inhibition of cryopyrin-associated periodic syndrome (CAPS)-associated mutant NLRP3 inflammasome by MCC950/CRID3: Reply ANR Weber, A Tapia-Abellán, X Liu, JI Aróstegui, P Pelegrín, T Welzel, ... Rheumatology 62 (5), e168-e169, 2023 | | 2023 |
