The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications FE Poynton, SA Bright, S Blasco, DC Williams, JM Kelly, T Gunnlaugsson Chemical Society Reviews 46 (24), 7706-7756, 2017 | 383 | 2017 |
Detailed biological profiling of a photoactivated and apoptosis inducing pdppz ruthenium (II) polypyridyl complex in cancer cells SM Cloonan, RBP Elmes, ML Erby, SA Bright, FE Poynton, DE Nolan, ... Journal of medicinal chemistry 58 (11), 4494-4505, 2015 | 99 | 2015 |
Nanotechnology based therapeutics for lung disease M Doroudian, R MacLoughlin, F Poynton, A Prina-Mello, SC Donnelly Thorax 74 (10), 965-976, 2019 | 92 | 2019 |
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy JP Hall, FE Poynton, PM Keane, SP Gurung, JA Brazier, DJ Cardin, ... Nature Chemistry 7 (12), 961-967, 2015 | 73 | 2015 |
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru (phen) 2 (dppz)] 2+ light-switch compound in solution and when … FE Poynton, JP Hall, PM Keane, C Schwarz, IV Sazanovich, M Towrie, ... Chemical Science 7 (5), 3075-3084, 2016 | 65 | 2016 |
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium (II) Dipyridophenazine Complex PM Keane, FE Poynton, JP Hall, IV Sazanovich, M Towrie, ... Angewandte Chemie International Edition 54 (29), 8364-8368, 2015 | 43 | 2015 |
Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1, 8-naphthalimide Ru (ii)-polypyridyl conjugates GJ Ryan, FE Poynton, RBP Elmes, M Erby, DC Williams, SJ Quinn, ... Dalton Transactions 44 (37), 16332-16344, 2015 | 43 | 2015 |
Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1, 8-naphthalimide derived Tröger's bases S Murphy, SA Bright, FE Poynton, T McCabe, JA Kitchen, EB Veale, ... Organic & biomolecular chemistry 12 (34), 6610-6623, 2014 | 42 | 2014 |
Enantiomeric conformation controls rate and yield of photoinduced electron transfer in DNA sensitized by Ru (II) Dipyridophenazine complexes PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ... The Journal of Physical Chemistry Letters 6 (4), 734-738, 2015 | 34 | 2015 |
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuII Complex due to Structural Change in the Minor Groove PM Keane, JP Hall, FE Poynton, BC Poulsen, SP Gurung, IP Clark, ... Chemistry–A European Journal 23 (43), 10344-10351, 2017 | 21 | 2017 |
Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with … PM Keane, K O'Sullivan, FE Poynton, BC Poulsen, IV Sazanovich, ... Chemical Science 11 (32), 8600-8609, 2020 | 20 | 2020 |
Bright SA Blasco S. Williams DC Kelly JM Gunnlaugsson T FE Poynton Chem. Soc. Rev 46, 7706-7756, 2017 | 17 | 2017 |
Caught in the Loop: Binding of the [Ru(phen)2(dppz)]2+ Light‐Switch Compound to Quadruplex DNA in Solution Informed by Time‐Resolved Infrared Spectroscopy SJ Devereux, FE Poynton, FR Baptista, T Gunnlaugsson, CJ Cardin, ... Chemistry–A European Journal 26 (71), 17103-17109, 2020 | 16 | 2020 |
Monitoring guanine photo-oxidation by enantiomerically resolved Ru (II) dipyridophenazine complexes using inosine-substituted oligonucleotides PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ... Faraday Discussions 185, 455-469, 2015 | 16 | 2015 |
Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics PM Keane, C Zehe, FE Poynton, SA Bright, S Estayalo-Adrián, ... Physical Chemistry Chemical Physics 24 (44), 27524-27531, 2022 | 7 | 2022 |
446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition P Joyce, L Young, M Quibell, J Shiers, C Tong, K Clark, E James, ... Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | 1 | 2020 |
Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilms, a potential novel therapeutic for cystic fibrosis patients A O'Neill, A Tynan, L Mawhinney, S Kennedy, E Caraher, FE Poynton, ... IRISH JOURNAL OF MEDICAL SCIENCE 186 (SUPPL 10), S420-S421, 2017 | 1 | 2017 |
Aerosolized nanodrug delivery system to inhibit Macrophage migration inhibitory factor in order to treat lung cancer M Doroudian, FE Poynton, C O'Reilly, K Crosbie-Staunton, ... Medicine 20 (1), 729-35, 2014 | 1 | 2014 |
Tracking the cellular uptake and phototoxicity of Ru (ii)-polypyridyl-1, 8-naphthalimide Tröger's base conjugates SA Bright, ML Erby, FE Poynton, D Monteyne, D Pérez-Morga, ... RSC Chemical Biology 5 (4), 344-359, 2024 | | 2024 |
Correction: Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron … PM Keane, C Zehe, FE Poynton, SA Bright, S Estayalo-Adrián, ... Physical Chemistry Chemical Physics 25 (34), 23316-23317, 2023 | | 2023 |