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Fergus E. Poynton
Fergus E. Poynton
Royal College of Surgeons in Ireland
在 tcd.ie 的电子邮件经过验证
标题
引用次数
引用次数
年份
The development of ruthenium (II) polypyridyl complexes and conjugates for in vitro cellular and in vivo applications
FE Poynton, SA Bright, S Blasco, DC Williams, JM Kelly, T Gunnlaugsson
Chemical Society Reviews 46 (24), 7706-7756, 2017
3832017
Detailed biological profiling of a photoactivated and apoptosis inducing pdppz ruthenium (II) polypyridyl complex in cancer cells
SM Cloonan, RBP Elmes, ML Erby, SA Bright, FE Poynton, DE Nolan, ...
Journal of medicinal chemistry 58 (11), 4494-4505, 2015
992015
Nanotechnology based therapeutics for lung disease
M Doroudian, R MacLoughlin, F Poynton, A Prina-Mello, SC Donnelly
Thorax 74 (10), 965-976, 2019
922019
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
JP Hall, FE Poynton, PM Keane, SP Gurung, JA Brazier, DJ Cardin, ...
Nature Chemistry 7 (12), 961-967, 2015
732015
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru (phen) 2 (dppz)] 2+ light-switch compound in solution and when …
FE Poynton, JP Hall, PM Keane, C Schwarz, IV Sazanovich, M Towrie, ...
Chemical Science 7 (5), 3075-3084, 2016
652016
Reversal of a Single Base‐Pair Step Controls Guanine Photo‐Oxidation by an Intercalating Ruthenium (II) Dipyridophenazine Complex
PM Keane, FE Poynton, JP Hall, IV Sazanovich, M Towrie, ...
Angewandte Chemie International Edition 54 (29), 8364-8368, 2015
432015
Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1, 8-naphthalimide Ru (ii)-polypyridyl conjugates
GJ Ryan, FE Poynton, RBP Elmes, M Erby, DC Williams, SJ Quinn, ...
Dalton Transactions 44 (37), 16332-16344, 2015
432015
Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1, 8-naphthalimide derived Tröger's bases
S Murphy, SA Bright, FE Poynton, T McCabe, JA Kitchen, EB Veale, ...
Organic & biomolecular chemistry 12 (34), 6610-6623, 2014
422014
Enantiomeric conformation controls rate and yield of photoinduced electron transfer in DNA sensitized by Ru (II) Dipyridophenazine complexes
PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ...
The Journal of Physical Chemistry Letters 6 (4), 734-738, 2015
342015
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuII Complex due to Structural Change in the Minor Groove
PM Keane, JP Hall, FE Poynton, BC Poulsen, SP Gurung, IP Clark, ...
Chemistry–A European Journal 23 (43), 10344-10351, 2017
212017
Understanding the factors controlling the photo-oxidation of natural DNA by enantiomerically pure intercalating ruthenium polypyridyl complexes through TA/TRIR studies with …
PM Keane, K O'Sullivan, FE Poynton, BC Poulsen, IV Sazanovich, ...
Chemical Science 11 (32), 8600-8609, 2020
202020
Bright SA Blasco S. Williams DC Kelly JM Gunnlaugsson T
FE Poynton
Chem. Soc. Rev 46, 7706-7756, 2017
172017
Caught in the Loop: Binding of the [Ru(phen)2(dppz)]2+ Light‐Switch Compound to Quadruplex DNA in Solution Informed by Time‐Resolved Infrared Spectroscopy
SJ Devereux, FE Poynton, FR Baptista, T Gunnlaugsson, CJ Cardin, ...
Chemistry–A European Journal 26 (71), 17103-17109, 2020
162020
Monitoring guanine photo-oxidation by enantiomerically resolved Ru (II) dipyridophenazine complexes using inosine-substituted oligonucleotides
PM Keane, FE Poynton, JP Hall, IP Clark, IV Sazanovich, M Towrie, ...
Faraday Discussions 185, 455-469, 2015
162015
Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics
PM Keane, C Zehe, FE Poynton, SA Bright, S Estayalo-Adrián, ...
Physical Chemistry Chemical Physics 24 (44), 27524-27531, 2022
72022
446 Immunopeptidome changes mediated by a novel ERAP1 inhibitor leads to tumor growth inhibition
P Joyce, L Young, M Quibell, J Shiers, C Tong, K Clark, E James, ...
Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020
12020
Macrophage migration inhibitory factor enhances Pseudomonas aeruginosa biofilms, a potential novel therapeutic for cystic fibrosis patients
A O'Neill, A Tynan, L Mawhinney, S Kennedy, E Caraher, FE Poynton, ...
IRISH JOURNAL OF MEDICAL SCIENCE 186 (SUPPL 10), S420-S421, 2017
12017
Aerosolized nanodrug delivery system to inhibit Macrophage migration inhibitory factor in order to treat lung cancer
M Doroudian, FE Poynton, C O'Reilly, K Crosbie-Staunton, ...
Medicine 20 (1), 729-35, 2014
12014
Tracking the cellular uptake and phototoxicity of Ru (ii)-polypyridyl-1, 8-naphthalimide Tröger's base conjugates
SA Bright, ML Erby, FE Poynton, D Monteyne, D Pérez-Morga, ...
RSC Chemical Biology 5 (4), 344-359, 2024
2024
Correction: Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron …
PM Keane, C Zehe, FE Poynton, SA Bright, S Estayalo-Adrián, ...
Physical Chemistry Chemical Physics 25 (34), 23316-23317, 2023
2023
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