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Armiyaw Sebastian Nasamu
Armiyaw Sebastian Nasamu
Post-doctoral fellow, Seattle Children's Research Institute, CGIDR
在 seattlechildrens.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes
SM Sidik, D Huet, SM Ganesan, MH Huynh, T Wang, AS Nasamu, P Thiru, ...
Cell 166 (6), 1423-1435. e12, 2016
7442016
Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites
SM Ganesan, A Falla, SJ Goldfless, AS Nasamu, JC Niles
Nature communications 7 (1), 10727, 2016
1862016
Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion
AS Nasamu, S Glushakova, I Russo, B Vaupel, A Oksman, AS Kim, ...
Science 358 (6362), 518-522, 2017
1762017
Muscle-specific SIRT1 gain-of-function increases slow-twitch fibers and ameliorates pathophysiology in a mouse model of duchenne muscular dystrophy
A Chalkiadaki, M Igarashi, AS Nasamu, J Knezevic, L Guarente
PLoS genetics 10 (7), e1004490, 2014
1552014
EXP2 is a nutrient-permeable channel in the vacuolar membrane of Plasmodium and is essential for protein export via PTEX
M Garten, AS Nasamu, JC Niles, J Zimmerberg, DE Goldberg, JR Beck
Nature microbiology 3 (10), 1090-1098, 2018
1272018
Malaria parasite plasmepsins: More than just plain old degradative pepsins
AS Nasamu, AJ Polino, ES Istvan, DE Goldberg
Journal of Biological Chemistry 295 (25), 8425-8441, 2020
682020
An integrated platform for genome engineering and gene expression perturbation in Plasmodium falciparum
AS Nasamu, A Falla, CFA Pasaje, BA Wall, JC Wagner, SM Ganesan, ...
Scientific reports 11 (1), 342, 2021
402021
Complex nutrient channel phenotypes despite Mendelian inheritance in a Plasmodium falciparum genetic cross
A Gupta, AAB Bokhari, AD Pillai, AK Crater, J Gezelle, G Saggu, ...
PLoS pathogens 16 (2), e1008363, 2020
392020
Rounding precedes rupture and breakdown of vacuolar membranes minutes before malaria parasite egress from erythrocytes
S Glushakova, JR Beck, M Garten, BL Busse, AS Nasamu, ...
Cellular microbiology 20 (10), e12868, 2018
392018
Assessment of Biological Role and Insight into Druggability of the Plasmodium falciparum Protease Plasmepsin V
AJ Polino, AS Nasamu, JC Niles, DE Goldberg
ACS Infectious Diseases 6 (4), 738-746, 2020
342020
Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages
S Singh, V Rajendran, J He, AK Singh, AO Achieng, Vandana, A Pant, ...
ACS Infectious Diseases 5 (2), 184-198, 2018
202018
4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl-N-benzylpyrrolidine-3-carboxamides
MJ Meyers, J Liu, J Xu, F Leng, J Guan, Z Liu, SA McNitt, L Qin, L Dai, ...
Journal of medicinal chemistry 62 (7), 3503-3512, 2019
172019
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation
S Bopp, CFA Pasaje, RL Summers, P Magistrado-Coxen, KA Schindler, ...
Nature Communications 14 (1), 1455, 2023
122023
Activation of the Plasmodium Egress Effector Subtilisin-Like Protease 1 Is Mediated by Plasmepsin X Destruction of the Prodomain
S Mukherjee, AS Nasamu, KC Rubiano, DE Goldberg
Mbio 14 (2), e00673-23, 2023
72023
GeneTargeter: Automated In Silico Design for Genome Editing in the Malaria Parasite, Plasmodium falciparum
P Cárdenas, LY Esherick, G Chambonnier, S Dey, CV Turlo, AS Nasamu, ...
The CRISPR Journal 5 (1), 155-164, 2022
62022
Exp2 in the role of the small molecule pore in the parasitophorous vacuole membrane of Plasmodium falciparum
M Garten, JR Beck, S Glushakova, AS Nasamu, JC Niles, DE Goldberg, ...
Biophysical Journal 114 (3), 492a, 2018
22018
Malaria parasites require a divergent heme oxygenase for apicoplast gene expression and biogenesis
AM Blackwell, Y Jami-Alahmadi, AS Nasamu, S Kudo, A Senoo, C Slam, ...
bioRxiv, 2024.05. 30.596652, 2024
12024
A NATURAL VARIANT IN PLASMODIUM FALCIPARUM ACYL CO-A SYNTHETASE 10 CONFERS RESISTANCE TO NOVEL ANTIMALARIALS
S Bopp, C Pasaje, P Magistrado-Coxen, R Summers, VC Lopez, S Dey, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 105 (5), 61-62, 2021
2021
The roles of plasmepsins IX and X in malaria parasite biology
AS Nasamu
Washington University in St. Louis, 2021
2021
Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages.
SS Snigdha Singh, VR Vinoth Rajendran, JH Jiang He, AK Singh, ...
2019
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