Optimization of key energy and performance metrics for drug product manufacturing Y Chen, L Kotamarthy, A Dan, C Sampat, P Bhalode, R Singh, BJ Glasser, ... International Journal of Pharmaceutics 631, 122487, 2023 | 14 | 2023 |
Enabling energy‐efficient manufacturing of pharmaceutical solid oral dosage forms via integrated techno‐economic analysis and advanced process modeling C Sampat, L Kotamarthy, P Bhalode, Y Chen, A Dan, S Parvani, ... Journal of Advanced Manufacturing and Processing 4 (4), e10136, 2022 | 14 | 2022 |
Twin-screw granulation: Mechanistic understanding of the effect of material properties on key granule quality attributes through the analysis of mixing dynamics and granulation … L Kotamarthy, A Dan, S Karkala, S Parvani, AD Román-Ospino, ... Advanced Powder Technology 34 (9), 104137, 2023 | 6 | 2023 |
End-point determination of heterogeneous formulations using inline torque measurements for a high-shear wet granulation process A Dan, H Vaswani, A Šimonová, A Grząbka-Zasadzińska, J Li, K Sen, ... International Journal of Pharmaceutics: X 6, 100188, 2023 | 5 | 2023 |
Multi-dimensional population balance model development using a breakage mode probability kernel for prediction of multiple granule attributes A Dan, H Vaswani, A Šimonová, R Ramachandran Pharmaceutical Development and Technology 28 (7), 638-649, 2023 | 3 | 2023 |
Understanding the effects of process parameters and material properties on the breakage mechanisms and regimes of a milling process A Dan, L Kotamarthy, R Ramachandran Chemical Engineering Research and Design 188, 607-619, 2022 | 3 | 2022 |
Investigating the Effects of Mixing Dynamics on Twin-Screw Granule Quality Attributes via the Development of a Physics-Based Process Map L Kotamarthy, S Karkala, A Dan, AD Román-Ospino, R Ramachandran Pharmaceutics 16 (4), 456, 2024 | 1 | 2024 |
Numerical modeling of fill-level and residence time in starve-fed single-screw extrusion: a dimensionality reduction study from a 3D CFD model to a 2D convection-diffusion model EH Olofsson, A Dan, M Roland, NH Jokil, R Ramachandran, JH Hattel The International Journal of Advanced Manufacturing Technology 132 (3), 1111 …, 2024 | | 2024 |
Semi-Mechanistic Prediction and Optimization of Residence Time Metrics of a Starve-Fed Extruder via a Hybrid Machine-Learning Convection–Diffusion Model A Dan, U Patil, EH Olofsson, JH Hattel, R Ramachandran Industrial & Engineering Chemistry Research 63 (16), 7271-7280, 2024 | | 2024 |
Quantitative analysis of the effects of multi-component formulation parameters on granule and tablet properties via a combined population balance and statistical predictive model A Dan, S Paul, H Vaswani, A Grząbka-Zasadzińska, A Thakkelapally, J Li, ... Powder Technology 435, 119391, 2024 | | 2024 |
Semi-Mechanistic Prediction of Residence Time Metrics and Mixing Dynamics in Single-Screw Extrusion Via a 2-D Convection-Diffusion Model Combined with Machine Learning A Dan, EH Olofsson, SV Muddu, NH Jokil, JH Hattel, R Ramachandran 2023 AIChE Annual Meeting, 2023 | | 2023 |
Energy efficient smart manufacturing of pharmaceutical solid oral dosage forms. A Dan, R Ramachandran Journal of Medical Science 92 (3), 2023 | | 2023 |
Development of Multi-Dimensional Population Balance Using a Breakage Mode Classification Kernel for the Prediction of Milled Granule Quality Attributes A Dan, R Ramachandran 2022 AIChE Annual Meeting, 2022 | | 2022 |