Brodalumab, an anti–interleukin-17–receptor antibody for psoriasis KA Papp, C Leonardi, A Menter, JP Ortonne, JG Krueger, G Kricorian, ... New England Journal of Medicine 366 (13), 1181-1189, 2012 | 1148 | 2012 |
The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings DA Martin, JE Towne, G Kricorian, P Klekotka, JE Gudjonsson, ... Journal of Investigative Dermatology 133 (1), 17-26, 2013 | 574 | 2013 |
The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses MA Lowes, CB Russell, DA Martin, JE Towne, JG Krueger Trends in immunology 34 (4), 174-181, 2013 | 561 | 2013 |
A prospective phase III, randomized, double‐blind, placebo‐controlled study of brodalumab in patients with moderate‐to‐severe plaque psoriasis KA Papp, K Reich, C Paul, A Blauvelt, W Baran, C Bolduc, D Toth, ... British Journal of Dermatology 175 (2), 273-286, 2016 | 497 | 2016 |
Multiyear follow-up of AAV5-hFVIII-SQ gene therapy for hemophilia A KJ Pasi, S Rangarajan, N Mitchell, W Lester, E Symington, B Madan, ... New England Journal of Medicine 382 (1), 29-40, 2020 | 438 | 2020 |
A randomized, double-blind, placebo-controlled phase 2 study of brodalumab in patients with moderate-to-severe Crohn’s disease SR Targan, B Feagan, S Vermeire, R Panaccione, GY Melmed, ... Official journal of the American College of Gastroenterology| ACG 111 (11 …, 2016 | 364 | 2016 |
Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial KA Papp, C Reid, P Foley, R Sinclair, DH Salinger, G Williams, H Dong, ... The Journal of investigative dermatology 132 (10), 2466-2469, 2012 | 185 | 2012 |
Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti–IL-17 receptor monoclonal antibody CB Russell, H Rand, J Bigler, K Kerkof, M Timour, E Bautista, JG Krueger, ... The Journal of Immunology 192 (8), 3828-3836, 2014 | 176 | 2014 |
A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1 DE Smith, BP Lipsky, C Russell, RR Ketchem, J Kirchner, K Hensley, ... Immunity 30 (6), 817-831, 2009 | 136 | 2009 |
A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant … DA Martin, M Churchill, LF Flores-Suarez, MH Cardiel, D Wallace, ... Arthritis research & therapy 15, 1-9, 2013 | 118 | 2013 |
Extremely short 20–33 nucleotide introns are the standard length in Paramecium tetraurelia CB Russell, D Fraga, RD Hinrichsen Nucleic acids research 22 (7), 1221-1225, 1994 | 99 | 1994 |
Cross-study homogeneity of psoriasis gene expression in skin across a large expression range J Bigler, HA Rand, K Kerkof, M Timour, CB Russell PloS one 8 (1), e52242, 2013 | 81 | 2013 |
Interindividual variability in transgene mRNA and protein production following adeno-associated virus gene therapy for hemophilia A S Fong, B Yates, CR Sihn, AN Mattis, N Mitchell, S Liu, CB Russell, B Kim, ... Nature medicine 28 (4), 789-797, 2022 | 80 | 2022 |
Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti–Interferon‐γ Antibody, in Patients With Discoid Lupus Erythematosus VP Werth, D Fiorentino, BA Sullivan, MJ Boedigheimer, K Chiu, C Wang, ... Arthritis & Rheumatology 69 (5), 1028-1034, 2017 | 71 | 2017 |
Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases A Nirula, J Nilsen, P Klekotka, G Kricorian, N Erondu, JE Towne, ... Rheumatology 55 (suppl_2), ii43-ii55, 2016 | 67 | 2016 |
Exchange of chromosomal and plasmid alleles in Escherichia coli by selection for loss of a dominant antibiotic sensitivity marker CB Russell, FW Dahlquist Journal of bacteriology 171 (5), 2614-2618, 1989 | 62 | 1989 |
Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes MA Tyler, CB Russell, DE Smith, JB Rottman, CJP Dietz, X Hu, MJ Citardi, ... Journal of Allergy and Clinical Immunology 139 (3), 1061-1064. e4, 2017 | 50 | 2017 |
Cellular responses to individual amino‐acid depletion in antibody‐expressing and parental CHO cell lines D Fomina‐Yadlin, JJ Gosink, R McCoy, B Follstad, A Morris, CB Russell, ... Biotechnology and Bioengineering 111 (5), 965-979, 2014 | 50 | 2014 |
Prospective–retrospective biomarker analysis for regulatory consideration: white paper from the industry pharmacogenomics working group SD Patterson, N Cohen, M Karnoub, SL Truter, E Emison, ... Pharmacogenomics 12 (7), 939-951, 2011 | 49 | 2011 |
Short-term transcriptional response to IL-17 receptor-A antagonism in the treatment of psoriasis LE Tomalin, CB Russell, S Garcet, DA Ewald, P Klekotka, A Nirula, ... Journal of Allergy and Clinical Immunology 145 (3), 922-932, 2020 | 48 | 2020 |