Discovery of Highly Potent Tyrosinase Inhibitor, T1, with Significant Anti-Melanogenesis Ability by zebrafish in vivo Assay and Computational Molecular Modeling WC Chen, TS Tseng, NW Hsiao, YL Lin, ZH Wen, CC Tsai, YC Lee, ... Scientific Reports 5 (1), 7995, 2015 | 170 | 2015 |
A comparison of different electrostatic potentials on prediction accuracy in CoMFA and CoMSIA studies KC Tsai, YC Chen, NW Hsiao, CL Wang, CL Lin, YC Lee, M Li, B Wang European Journal of Medicinal Chemistry 45 (4), 1544-1551, 2010 | 80 | 2010 |
Artificial intelligence-assisted fast screening cervical high grade squamous intraepithelial lesion and squamous cell carcinoma diagnosis and treatment planning CW Wang, YA Liou, YJ Lin, CC Chang, PH Chu, YC Lee, CH Wang, ... Scientific Reports 11 (1), 16244, 2021 | 69 | 2021 |
Identification of salt-inducible kinase 3 as a novel tumor antigen associated with tumorigenesis of ovarian cancer S Charoenfuprasert, YY Yang, YC Lee, KC Chao, PY Chu, CR Lai, ... Oncogene 30 (33), 3570-3584, 2011 | 69 | 2011 |
Deep learning for bone marrow cell detection and classification on whole-slide images CW Wang, SC Huang, YC Lee, YJ Shen, SI Meng, JL Gaol Medical image analysis 75, 102270, 2022 | 66 | 2022 |
Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface CM Yu, HP Peng, IC Chen, YC Lee, JB Chen, KC Tsai, CT Chen, ... PLoS One 7 (3), e33340, 2012 | 60 | 2012 |
Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer CH Chen, CA Changou, TH Hsieh, YC Lee, CY Chu, KC Hsu, HC Wang, ... Clinical Cancer Research 24 (5), 1176-1189, 2018 | 52 | 2018 |
Serendipitous discovery of short peptides from natural products as tyrosinase inhibitors NW Hsiao, TS Tseng, YC Lee, WC Chen, HH Lin, YR Chen, YT Wang, ... Journal of chemical information and modeling 54 (11), 3099-3111, 2014 | 49 | 2014 |
Mitochondrial translocation of estrogen receptor β affords resistance to oxidative insult-induced apoptosis and contributes to the pathogenesis of endometriosis TL Liao, YC Lee, CR Tzeng, YP Wang, HY Chang, YF Lin, SH Kao Free Radical Biology and Medicine 134, 359-373, 2019 | 40 | 2019 |
Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells MW Chao, TH Chen, HL Huang, YW Chang, WC HuangFu, YC Lee, ... Scientific reports 7 (1), 46134, 2017 | 40 | 2017 |
Deep learning fast screening approach on cytological whole slides for thyroid cancer diagnosis YJ Lin, TK Chao, MA Khalil, YC Lee, DZ Hong, JJ Wu, CW Wang Cancers 13 (15), 3891, 2021 | 38 | 2021 |
Development and clinical applications of cancer immunotherapy against PD-1 signaling pathway G Wakabayashi, YC Lee, F Luh, CN Kuo, WC Chang, Y Yen Journal of Biomedical Science 26, 1-13, 2019 | 38 | 2019 |
Loop-sequence features and stability determinants in antibody variable domains by high-throughput experiments HJ Chang, JW Jian, HJ Hsu, YC Lee, HS Chen, JJ You, SC Hou, CY Shao, ... Structure 22 (1), 9-21, 2014 | 38 | 2014 |
Discovery of potent cysteine-containing dipeptide inhibitors against tyrosinase: a comprehensive investigation of 20× 20 dipeptides in inhibiting dopachrome formation TS Tseng, KC Tsai, WC Chen, YT Wang, YC Lee, CK Lu, MJ Don, ... Journal of agricultural and food chemistry 63 (27), 6181-6188, 2015 | 36 | 2015 |
Weakly supervised deep learning for prediction of treatment effectiveness on ovarian cancer from histopathology images CW Wang, CC Chang, YC Lee, YJ Lin, SC Lo, PC Hsu, YA Liou, ... Computerized Medical Imaging and Graphics 99, 102093, 2022 | 35 | 2022 |
Antibodies against Venom of the Snake Deinagkistrodon acutus CH Lee, YC Lee, MH Liang, SJ Leu, LT Lin, JR Chiang, YY Yang Applied and environmental microbiology 82 (1), 71-80, 2016 | 34 | 2016 |
PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression YD Lang, HY Chen, CM Ho, JH Shih, EC Hsu, R Shen, YC Lee, JW Chen, ... Nature Communications 10 (1), 5716, 2019 | 31 | 2019 |
Antibody variable domain interface and framework sequence requirements for stability and function by high-throughput experiments HJ Hsu, KH Lee, JW Jian, HJ Chang, CM Yu, YC Lee, C Chen, HP Peng, ... Structure 22 (1), 22-34, 2014 | 30 | 2014 |
The ethyl acetate fraction of corn silk exhibits dual antioxidant and anti-glycation activities and protects insulin-secreting cells from glucotoxicity CC Chang, W Yuan, HY Roan, JL Chang, HC Huang, YC Lee, HJ Tsay, ... BMC complementary and alternative medicine 16, 1-11, 2016 | 29 | 2016 |
A weakly supervised deep learning method for guiding ovarian cancer treatment and identifying an effective biomarker CW Wang, YC Lee, CC Chang, YJ Lin, YA Liou, PC Hsu, CC Chang, ... Cancers 14 (7), 1651, 2022 | 28 | 2022 |