Commonalities in epileptogenic processes from different acute brain insults: Do they translate? P Klein, R Dingledine, E Aronica, C Bernard, I Blümcke, D Boison, ... Epilepsia 59 (1), 37-66, 2018 | 260 | 2018 |
SV2A protein is a broad-spectrum anticonvulsant target: functional correlation between protein binding and seizure protection in models of both partial and generalized epilepsy RM Kaminski, A Matagne, K Leclercq, M Gillard, P Michel, B Kenda, ... Neuropharmacology 54 (4), 715-720, 2008 | 204 | 2008 |
Allopregnanolone Analogs That Positively Modulate GABAA Receptors Protect against Partial Seizures Induced by 6‐Hz Electrical Stimulation in Mice RM Kaminski, MR Livingood, MA Rogawski Epilepsia 45 (7), 864-867, 2004 | 203 | 2004 |
Neuroinflammatory targets and treatments for epilepsy validated in experimental models E Aronica, S Bauer, Y Bozzi, M Caleo, R Dingledine, JA Gorter, ... Epilepsia 58, 27-38, 2017 | 175 | 2017 |
Topiramate selectively protects against seizures induced by ATPA, a GluR5 kainate receptor agonist RM Kaminski, M Banerjee, MA Rogawski Neuropharmacology 46 (8), 1097-1104, 2004 | 173 | 2004 |
Synaptic vesicle glycoprotein 2A ligands in the treatment of epilepsy and beyond W Löscher, M Gillard, ZA Sands, RM Kaminski, H Klitgaard CNS drugs 30, 1055-1077, 2016 | 165 | 2016 |
Brivaracetam: Rationale for discovery and preclinical profile of a selective SV 2A ligand for epilepsy treatment H Klitgaard, A Matagne, JM Nicolas, M Gillard, Y Lamberty, M De Ryck, ... Epilepsia 57 (4), 538-548, 2016 | 160 | 2016 |
Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus MR Johnson, J Behmoaras, L Bottolo, ML Krishnan, K Pernhorst, ... Nature communications 6 (1), 6031, 2015 | 157 | 2015 |
Proepileptic phenotype of SV2A‐deficient mice is associated with reduced anticonvulsant efficacy of levetiracetam RM Kaminski, M Gillard, K Leclercq, E Hanon, G Lorent, D Dassesse, ... Epilepsia 50 (7), 1729-1740, 2009 | 149 | 2009 |
Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease MR Johnson, K Shkura, SR Langley, A Delahaye-Duriez, P Srivastava, ... Nature neuroscience 19 (2), 223-232, 2016 | 138 | 2016 |
Nrf2 defense pathway: Experimental evidence for its protective role in epilepsy M Mazzuferi, G Kumar, J van Eyll, B Danis, P Foerch, RM Kaminski Annals of neurology 74 (4), 560-568, 2013 | 135 | 2013 |
Anticonvulsant activity of androsterone and etiocholanolone RM Kaminski, H Marini, WJ Kim, MA Rogawski Epilepsia 46 (6), 819-827, 2005 | 123 | 2005 |
Rapid epileptogenesis in the mouse pilocarpine model: video-EEG, pharmacokinetic and histopathological characterization M Mazzuferi, G Kumar, C Rospo, RM Kaminski Experimental neurology 238 (2), 156-167, 2012 | 122 | 2012 |
Benefit of combination therapy in epilepsy: a review of the preclinical evidence with levetiracetam RM Kaminski, A Matagne, PN Patsalos, H Klitgaard Epilepsia 50 (3), 387-397, 2009 | 120 | 2009 |
Opportunities for improving animal welfare in rodent models of epilepsy and seizures K Lidster, JG Jefferys, I Blümcke, V Crunelli, P Flecknell, BG Frenguelli, ... Journal of neuroscience methods 260, 2-25, 2016 | 110 | 2016 |
Issues related to development of antiepileptogenic therapies A Pitkänen, A Nehlig, AR Brooks‐Kayal, FE Dudek, D Friedman, ... Epilepsia 54, 35-43, 2013 | 106 | 2013 |
The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments RM Kaminski, MA Rogawski, H Klitgaard Neurotherapeutics 11 (2), 385-400, 2014 | 105 | 2014 |
Influence of melatonin upon the protective action of conventional anti-epileptic drugs against maximal electroshock in mice KK Borowicz, R Kamiński, M Gasior, Z Kleinrok, SJ Czuczwar European neuropsychopharmacology 9 (3), 185-190, 1999 | 102 | 1999 |
Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery A Delahaye-Duriez, P Srivastava, K Shkura, SR Langley, L Laaniste, ... Genome biology 17, 1-18, 2016 | 94 | 2016 |
n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis F Frigerio, G Pasqualini, I Craparotta, S Marchini, EA van Vliet, P Foerch, ... Brain 141 (11), 3130-3143, 2018 | 89 | 2018 |