Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration JB O'Sullivan, KM Ryan, NM Curtin, A Harkin, TJ Connor International Journal of Neuropsychopharmacology 12 (5), 687-699, 2009 | 153 | 2009 |
Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex EN McNamee, ÉW Griffin, KM Ryan, KJ Ryan, S Heffernan, A Harkin, ... Neuropharmacology 59 (1-2), 37-48, 2010 | 83 | 2010 |
Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory … JB O'Sullivan, KM Ryan, A Harkin, TJ Connor Journal of neuroimmunology 220 (1-2), 34-42, 2010 | 75 | 2010 |
Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1β-induced neurotoxicity EN McNamee, KM Ryan, D Kilroy, TJ Connor European journal of pharmacology 626 (2-3), 219-228, 2010 | 73 | 2010 |
Noradrenaline acting at central β-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration EN McNamee, KM Ryan, ÉW Griffin, RE González-Reyes, KJ Ryan, ... Brain, behavior, and immunity 24 (4), 660-671, 2010 | 71 | 2010 |
When less is more–microRNAs and psychiatric disorders E Kolshus, VS Dalton, KM Ryan, DM McLoughlin Acta psychiatrica scandinavica 129 (4), 241-256, 2014 | 60 | 2014 |
BDNF plasma levels and genotype in depression and the response to electroconvulsive therapy KM Ryan, R Dunne, DM McLoughlin Brain stimulation 11 (5), 1123-1131, 2018 | 57 | 2018 |
Electroconvulsive stimulation alters levels of BDNF-associated microRNAs KM Ryan, SM O’Donovan, DM McLoughlin Neuroscience letters 549, 125-129, 2013 | 56 | 2013 |
Peripheral blood microRNA and VEGFA mRNA changes following electroconvulsive therapy: implications for psychotic depression E Kolshus, KM Ryan, G Blackshields, P Smyth, O Sheils, DM McLoughlin Acta Psychiatrica Scandinavica 136 (6), 594-606, 2017 | 45 | 2017 |
Microglia and their LAG3 checkpoint underlie the antidepressant and neurogenesis-enhancing effects of electroconvulsive stimulation N Rimmerman, H Verdiger, H Goldenberg, L Naggan, E Robinson, ... Molecular Psychiatry 27 (2), 1120-1135, 2022 | 38 | 2022 |
Tryptophan metabolite concentrations in depressed patients before and after electroconvulsive therapy KM Ryan, KA Allers, DM McLoughlin, A Harkin Brain, Behavior, and Immunity 83, 153-162, 2020 | 38 | 2020 |
Stimulation of central β2-adrenoceptors suppresses NFκB activity in rat brain: a role for IκB KJ Ryan, É Griffin, JD Yssel, KM Ryan, EN McNamee, A Harkin, ... Neurochemistry international 63 (5), 368-378, 2013 | 28 | 2013 |
Peroxisome proliferator-activated receptor gamma co-activator-1 alpha in depression and the response to electroconvulsive therapy KM Ryan, I Patterson, DM McLoughlin Psychological Medicine 49 (11), 1859-1868, 2019 | 23 | 2019 |
Peripheral blood SIRT1 mRNA levels in depression and treatment with electroconvulsive therapy CL McGrory, KM Ryan, E Kolshus, M Finnegan, DM McLoughlin European Neuropsychopharmacology 28 (9), 1015-1023, 2018 | 23 | 2018 |
Electroconvulsive therapy modulates plasma pigment epithelium-derived factor in depression: a proteomics study KM Ryan, A Glaviano, SM O'donovan, E Kolshus, R Dunne, A Kavanagh, ... Translational psychiatry 7 (3), e1073-e1073, 2017 | 23 | 2017 |
Blood plasma B vitamins in depression and the therapeutic response to electroconvulsive therapy KM Ryan, KA Allers, A Harkin, DM McLoughlin Brain, behavior, & immunity-health 4, 100063, 2020 | 18 | 2020 |
Dexamethasone attenuates inflammatory-mediated suppression of β2-adrenoceptor expression in rat primary mixed glia KM Ryan, NT Boyle, A Harkin, TJ Connor Journal of Neuroimmunology 338, 577082, 2020 | 17 | 2020 |
Ketamine versus midazolam for depression relapse prevention following successful electroconvulsive therapy: a randomized controlled pilot trial M Finnegan, T Galligan, K Ryan, E Shanahan, A Harkin, L Daly, ... The Journal of ECT 35 (2), 115-121, 2019 | 17 | 2019 |
Vascular endothelial growth factor plasma levels in depression and following electroconvulsive therapy KM Ryan, DM McLoughlin European Archives of Psychiatry and Clinical Neuroscience 268 (8), 839-848, 2018 | 17 | 2018 |
Interrogating Associations Between Polygenic Liabilities and Electroconvulsive Therapy Effectiveness JJ Luykx, D Loef, B Lin, L van Diermen, JO Nuninga, E van Exel, ... Biological psychiatry 91 (6), 531-539, 2022 | 16 | 2022 |