| Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ... Science 277 (5325), 567-570, 1997 | 1643 | 1997 |
| Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ... Science 279 (5351), 710-714, 1998 | 1429 | 1998 |
| PI3K signalling: the path to discovery and understanding B Vanhaesebroeck, L Stephens, P Hawkins Nature reviews Molecular cell biology 13 (3), 195-203, 2012 | 1100 | 2012 |
| A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits L Stephens, A Smrcka, FT Cooke, TR Jackson, PC Sternweis, PT Hawkins Cell 77 (1), 83-93, 1994 | 793 | 1994 |
| Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase γ ME Pacold, S Suire, O Perisic, S Lara-Gonzalez, CT Davis, EH Walker, ... Cell 103 (6), 931-944, 2000 | 790 | 2000 |
| The Gβγ sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101 LR Stephens, A Eguinoa, H Erdjument-Bromage, M Lui, F Cooke, ... Cell 89 (1), 105-114, 1997 | 732 | 1997 |
| Signalling through Class I PI3Ks in mammalian cells PT Hawkins, KE Anderson, K Davidson, LR Stephens Biochemical Society Transactions 34 (5), 647-662, 2006 | 723 | 2006 |
| PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase PT Hawkins, A Eguinoa, RG Qiu, D Stokoe, FT Cooke, R Walters, ... Current Biology 5 (4), 393-403, 1995 | 700 | 1995 |
| P-Rex1, a PtdIns (3, 4, 5) P3-and Gβγ-regulated guanine-nucleotide exchange factor for Rac HCE Welch, WJ Coadwell, CD Ellson, GJ Ferguson, SR Andrews, ... Cell 108 (6), 809-821, 2002 | 675 | 2002 |
| Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage I Angulo, O Vadas, F Garçon, E Banham-Hall, V Plagnol, TR Leahy, ... Science 342 (6160), 866-871, 2013 | 645 | 2013 |
| Agonist-stimulated synthesis of phosphatidylinositol (3, 4, 5)-trisphosphate: a new intracellular signalling system? LR Stephens, TR Jackson, PT Hawkins Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1179 (1), 27-75, 1993 | 625 | 1993 |
| Rapid breakdown of phosphatidylinositol 4-phosphate and phosphatidylinositol 4, 5-bisphosphate in rat hepatocytes stimulated by vasopressin and other Ca2+-mobilizing hormones JA Creba, CP Downes, PT Hawkins, G Brewster, RH Michell, CJ Kirk Biochemical Journal 212 (3), 733-747, 1983 | 623 | 1983 |
| Activation of the small GTP-binding proteins rho and rac by growth factor receptors CD Nobes, P Hawkins, L Stephens, A Hall Journal of cell science 108 (1), 225-233, 1995 | 594 | 1995 |
| Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling S Wennström, P Hawkins, F Cooke, K Hara, K Yonezawa, M Kasuga, ... Current Biology 4 (5), 385-393, 1994 | 552 | 1994 |
| PI3K signalling in inflammation PT Hawkins, LR Stephens Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2015 | 545 | 2015 |
| Translocation of PDK-1 to the plasma membrane is important in allowing PDK-1 to activate protein kinase B KE Anderson, J Coadwell, LR Stephens, PT Hawkins Current Biology 8 (12), 684-691, 1998 | 505 | 1998 |
| PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40(phox). SLR Ellson CD, Gobert-Gosse S, Anderson KE, Davidson K, Erdjument-Bromage H ... nature cell biology 3 (7), 679-82, 2001 | 490 | 2001 |
| Phosphoinositide 3-kinase-dependent activation of Rac HCE Welch, WJ Coadwell, LR Stephens, PT Hawkins FEBS letters 546 (1), 93-97, 2003 | 446 | 2003 |
| Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils AM Condliffe, K Davidson, KE Anderson, CD Ellson, T Crabbe, ... Blood 106 (4), 1432-1440, 2005 | 387 | 2005 |
| Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices S Krugmann, KE Anderson, SH Ridley, N Risso, A McGregor, J Coadwell, ... Molecular cell 9 (1), 95-108, 2002 | 358 | 2002 |
