Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ KS Molnar, M Bonomi, R Pellarin, GD Clinthorne, G Gonzalez, ... Structure 22 (9), 1239-1251, 2014 | 124 | 2014 |
Mixed quantum mechanical/molecular mechanical (QM/MM) study of the deacylation reaction in a penicillin binding protein (PBP) versus in a class C β-lactamase BF Gherman, SD Goldberg, VW Cornish, RA Friesner Journal of the American Chemical Society 126 (24), 7652-7664, 2004 | 105 | 2004 |
Site-specific protein modification using immobilized sortase in batch and continuous-flow systems MD Witte, T Wu, CP Guimaraes, CS Theile, AEM Blom, JR Ingram, Z Li, ... Nature protocols 10 (3), 508-516, 2015 | 74 | 2015 |
Engineering a targeted delivery platform using Centyrins SD Goldberg, RMF Cardoso, T Lin, T Spinka-Doms, D Klein, SA Jacobs, ... Protein Engineering, Design and Selection 29 (12), 563-572, 2016 | 61 | 2016 |
Transmembrane polar interactions are required for signaling in the Escherichia coli sensor kinase PhoQ SD Goldberg, GD Clinthorne, M Goulian, WF DeGrado Proceedings of the National Academy of Sciences 107 (18), 8141-8146, 2010 | 59 | 2010 |
Identification of residues critical for catalysis in a class C β‐lactamase by combinatorial scanning mutagenesis SD Goldberg, W Iannuccilli, T Nguyen, J Ju, VW Cornish Protein science 12 (8), 1633-1645, 2003 | 58 | 2003 |
Centyrin ligands for extrahepatic delivery of siRNA D Klein, S Goldberg, CS Theile, R Dambra, K Haskell, E Kuhar, T Lin, ... Molecular Therapy 29 (6), 2053-2066, 2021 | 37 | 2021 |
Evaluation of a centyrin-based near-infrared probe for fluorescence-guided surgery of epidermal growth factor receptor positive tumors SM Mahalingam, VY Dudkin, S Goldberg, D Klein, F Yi, S Singhal, ... Bioconjugate chemistry 28 (11), 2865-2873, 2017 | 31 | 2017 |
Engineered single‐ and multi‐cell chemotaxis pathways in E. coli SD Goldberg, P Derr, WF DeGrado, M Goulian Molecular Systems Biology 5 (1), 283, 2009 | 29 | 2009 |
Determination of the physiological dimer interface of the PhoQ sensor domain SD Goldberg, CS Soto, CD Waldburger, WF DeGrado Journal of molecular biology 379 (4), 656-665, 2008 | 26 | 2008 |
Correlation between catalytic efficiency and the transcription read-out in chemical complementation: a general assay for enzyme catalysis D Sengupta, H Lin, SD Goldberg, JJ Mahal, VW Cornish Biochemistry 43 (12), 3570-3581, 2004 | 20 | 2004 |
LC/MS/MS bioanalysis of protein–drug conjugates—the importance of incorporating succinimide hydrolysis products C Shi, S Goldberg, T Lin, V Dudkin, W Widdison, L Harris, S Wilhelm, ... Analytical chemistry 90 (8), 5314-5321, 2018 | 16 | 2018 |
Cysteine engineered fibronectin type iii domain binding molecules S Goldberg, S Jacobs, T Lin, K O'neil | 16 | 2015 |
Bioanalytical workflow for novel scaffold protein–drug conjugates: quantitation of total Centyrin protein, conjugated Centyrin and free payload for Centyrin–drug conjugate in … C Shi, S Goldberg, T Lin, V Dudkin, W Widdison, L Harris, S Wilhelm, ... Bioanalysis 10 (20), 1651-1665, 2018 | 15 | 2018 |
Prostate specific membrane antigen binding fibronectin type III domains R Cardoso, M Diem, S Goldberg, L Hyun, S Jacobs, D Klein, K O'neil, ... US Patent 10,844,111, 2020 | 14 | 2020 |
Investigation of the Mechanism of Resistance to Third‐Generation Cephalosporins by Class C β‐Lactamases by Using Chemical Complementation BT Carter, H Lin, SD Goldberg, EA Althoff, J Raushel, VW Cornish Chembiochem 6 (11), 2055-2067, 2005 | 13 | 2005 |
Prostate specific membrane antigen (PSMA) bispecific binding agents and uses thereof G Anderson, R Cardoso, M Diem, F Gaudet, S Goldberg, B Harman, ... US Patent 10,844,122, 2020 | 10 | 2020 |
Targeting with fibronectin type iii like domain molecules V Dudkin, A Elias, S Goldberg, D Klein, E Kuhar, T Lin, L Peddada, ... | 8 | 2019 |
Cysteine engineered fibronectin type III domain binding molecules M Anderson, R Attar, M Diem, L Hyun, A King, S Jacobs, S Goldberg, ... US Patent 10,662,235, 2020 | 7 | 2020 |
A strategy for selective deletion of autoimmunity-related T cells by pMHC-targeted delivery SD Goldberg, N Felix, M McCauley, R Eberwine, L Casta, K Haskell, T Lin, ... Pharmaceutics 13 (10), 1669, 2021 | 2 | 2021 |