SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer Y Xue, B Meehan, Z Fu, XQD Wang, PO Fiset, R Rieker, C Levins, T Kong, ... Nature communications 10 (1), 557, 2019 | 163 | 2019 |
CD44 promotes PD-L1 expression and its tumor-intrinsic function in breast and lung cancers T Kong, R Ahn, K Yang, X Zhu, Z Fu, G Morin, R Bramley, NC Cliffe, Y Xue, ... Cancer research 80 (3), 444-457, 2020 | 121 | 2020 |
CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary Y Xue, B Meehan, E Macdonald, S Venneti, XQD Wang, L Witkowski, ... Nature communications 10 (1), 558, 2019 | 121 | 2019 |
The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer S Adam, SE Rossi, N Moatti, M De Marco Zompit, Y Xue, TF Ng, ... Nature cancer 2 (12), 1357-1371, 2021 | 76 | 2021 |
SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer AI Papadakis, C Sun, TA Knijnenburg, Y Xue, W Grernrum, M Hölzel, ... Cell research 25 (4), 445-458, 2015 | 70 | 2015 |
eIF4A inhibitors suppress cell-cycle feedback response and acquired resistance to CDK4/6 inhibition in cancer T Kong, Y Xue, R Cencic, X Zhu, A Monast, Z Fu, V Pilon, V Sangwan, ... Molecular cancer therapeutics 18 (11), 2158-2170, 2019 | 45 | 2019 |
Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer S McGuirk, Y Audet-Delage, MG Annis, Y Xue, M Vernier, K Zhao, ... Elife 10, e65150, 2021 | 40 | 2021 |
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria Y Xue, JL Morris, K Yang, Z Fu, X Zhu, F Johnson, B Meehan, L Witkowski, ... Nature communications 12 (1), 5404, 2021 | 33 | 2021 |
Interaction of serum microRNAs and serum folate with the susceptibility to pancreatic cancer Y Tian, Y Xue, G Ruan, K Cheng, J Tian, Q Qiu, M Xiao, H Li, H Yang, ... Pancreas 44 (1), 23-30, 2015 | 18 | 2015 |
SMARCB1 loss induces druggable cyclin D1 deficiency via upregulation of MIR17HG in atypical teratoid rhabdoid tumors Y Xue, X Zhu, B Meehan, S Venneti, D Martinez, G Morin, RI Maïga, ... The Journal of Pathology 252 (1), 77-87, 2020 | 15 | 2020 |
Cotargeting CDK4/6 and BRD4 Promotes Senescence and Ferroptosis Sensitivity in Cancer X Zhu, Z Fu, K Dutchak, A Arabzadeh, S Milette, J Steinberger, G Morin, ... Cancer Research 84 (8), 1333-1351, 2024 | 6 | 2024 |
A mitotic glue for shattered chromosomes Y Xue, D Durocher Nature 618 (7967), 909-910, 2023 | 1 | 2023 |