Nucleated conformational conversion and the replication of conformational information by a prion determinant TR Serio, AG Cashikar, AS Kowal, GJ Sawicki, JJ Moslehi, L Serpell, ... Science 289 (5483), 1317-1321, 2000 | 1187 | 2000 |
The prion hypothesis: from biological anomaly to basic regulatory mechanism MF Tuite, TR Serio Nature reviews Molecular cell biology 11 (12), 823-833, 2010 | 179 | 2010 |
Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance P Satpute-Krishnan, SX Langseth, TR Serio PLoS biology 5 (2), e24, 2007 | 161 | 2007 |
[PSI+]: An Epigenetic Modulator of Translation Termination Efficiency TR Serio, SL Lindquist Annual review of cell and developmental biology 15 (1), 661-703, 1999 | 129 | 1999 |
Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding WM Holmes, BK Mannakee, RN Gutenkunst, TR Serio Nature communications 5 (1), 4383, 2014 | 123 | 2014 |
A size threshold limits prion transmission and establishes phenotypic diversity A Derdowski, SS Sindi, CL Klaips, S DiSalvo, TR Serio Science 330 (6004), 680-683, 2010 | 122 | 2010 |
Prion protein remodelling confers an immediate phenotypic switch P Satpute-Krishnan, TR Serio Nature 437 (7056), 262-265, 2005 | 105 | 2005 |
[41] Yeast prion [Ψ+] and its determinant, sup35p TR Serio, AG Cashikar, JJ Moslehi, AS Kowal, SL Lindquist Methods in enzymology 309, 649-673, 1999 | 104 | 1999 |
Protein-only inheritance in yeast: something to get [PSI+]-ched about TR Serio, SL Lindquist Trends in Cell Biology 10 (3), 98-105, 2000 | 102 | 2000 |
Late gene expression from the Epstein-Barr virus BcLF1 and BFRF3 promoters does not require DNA replication in cis TR Serio, JL Kolman, G Miller Journal of virology 71 (11), 8726-8734, 1997 | 56 | 1997 |
Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation S DiSalvo, A Derdowski, JA Pezza, TR Serio Nature structural & molecular biology 18 (4), 486-492, 2011 | 53 | 2011 |
Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing CL Klaips, ML Hochstrasser, CR Langlois, TR Serio Elife 3, e04288, 2014 | 52 | 2014 |
A functionally distinct TATA box required for late progression through the Epstein-Barr virus life cycle TR Serio, N Cahill, ME Prout, G Miller Journal of virology 72 (10), 8338-8343, 1998 | 51 | 1998 |
Prion dynamics and the quest for the genetic determinant in protein-only inheritance SS Sindi, TR Serio Current opinion in microbiology 12 (6), 623-630, 2009 | 48 | 2009 |
Amyloid-associated activity contributes to the severity and toxicity of a prion phenotype JA Pezza, J Villali, SS Sindi, TR Serio Nature communications 5 (1), 4384, 2014 | 45 | 2014 |
Defining the limits: Protein aggregation and toxicity in vivo WM Holmes, CL Klaips, TR Serio Critical reviews in biochemistry and molecular biology 49 (4), 294-303, 2014 | 41 | 2014 |
Estimating the rate of prion aggregate amplification in yeast with a generation and structured population model HT Banks, KB Flores, CR Langlois, TR Serio, SS Sindi Inverse Problems in Science and Engineering 26 (2), 257-279, 2018 | 39 | 2018 |
Two 21-kilodalton components of the Epstein-Barr virus capsid antigen complex and their relationship to ZEBRA-associated protein p21 (ZAP21) TR Serio, A Angeloni, JL Kolman, L Gradoville, R Sun, DA Katz, ... Journal of virology 70 (11), 8047-8054, 1996 | 38 | 1996 |
The yeast prion [PSI+]: molecular insights and functional consequences TR Serio, SL Lindquist Advances in protein chemistry 59, 391-412, 2001 | 32 | 2001 |
Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast J Villali, J Dark, TM Brechtel, F Pei, SS Sindi, TR Serio Nature structural & molecular biology 27 (6), 540-549, 2020 | 30 | 2020 |