Toxicity testing in the 21st century: a vision and a strategy D Krewski, D Acosta Jr, M Andersen, H Anderson, JC Bailar III, ... Journal of Toxicology and Environmental Health, Part B 13 (2-4), 51-138, 2010 | 887 | 2010 |
Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL/6J mice JR Fowles, A Fairbrother, L Baecher-Steppan, NI Kerkvliet Toxicology 86 (1-2), 49-61, 1994 | 350 | 1994 |
Recent advances in understanding the mechanisms of TCDD immunotoxicity NI Kerkvliet International immunopharmacology 2 (2-3), 277-291, 2002 | 277 | 2002 |
Cutting edge: activation of the aryl hydrocarbon receptor by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin generates a population of CD4+ CD25+ cells with characteristics of … CJ Funatake, NB Marshall, LB Steppan, DV Mourich, NI Kerkvliet The Journal of Immunology 175 (7), 4184-4188, 2005 | 273 | 2005 |
AHR-mediated immunomodulation: the role of altered gene transcription NI Kerkvliet Biochemical pharmacology 77 (4), 746-760, 2009 | 219 | 2009 |
Dioxin and immune regulation: emerging role of aryl hydrocarbon receptor in the generation of regulatory T cells NB Marshall, NI Kerkvliet Annals of the New York Academy of Sciences 1183 (1), 25-37, 2010 | 218 | 2010 |
Immunological effects of chlorinated dibenzo-p-dioxins. NI Kerkvliet Environmental Health Perspectives 103 (suppl 9), 47-53, 1995 | 196 | 1995 |
Aryl hydrocarbon receptor-deficient mice generate normal immune responses to model antigens and are resistant to TCDD-induced immune suppression BA Vorderstrasse, LB Steppan, AE Silverstone, NI Kerkvliet Toxicology and applied pharmacology 171 (3), 157-164, 2001 | 195 | 2001 |
Activation of Aryl Hydrocarbon Receptor by Tcdd Prevents Diabetes in Nod Mice and Increases Foxp3+ T Cells in Pancreatic Lymph Nodes NI Kerkvliet, LB Steppan, W Vorachek, S Oda, D Farrer, CP Wong, ... Immunotherapy 1 (4), 539-547, 2009 | 192 | 2009 |
Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands WH Bisson, DC Koch, EF O’Donnell, SM Khalil, NI Kerkvliet, RL Tanguay, ... Journal of medicinal chemistry 52 (18), 5635-5641, 2009 | 169 | 2009 |
Pyridoxine supplementation: effect on lymphocyte responses in elderly persons MC Talbott, LT Miller, NI Kerkvliet The American journal of clinical nutrition 46 (4), 659-664, 1987 | 166 | 1987 |
Role of the Ah locus in suppression of cytotoxic T lymphocyte activity by halogenated aromatic hydrocarbons (PCBs and TCDD): structure-activity relationships and effects in … NI Kerkvliet, BB Smith, LB STEPPAN, JA Youngberg, MC Henderson, ... Toxicological Sciences 14 (3), 532-541, 1990 | 162 | 1990 |
T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is … NI Kerkvliet, DM Shepherd, L Baecher-Steppan Toxicology and applied pharmacology 185 (2), 146-152, 2002 | 155 | 2002 |
Influence of the Ah locus on the humoral immunotoxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin: evidence for Ah-receptor-dependent and Ah-receptor-independent mechanisms of … NI Kerkvliet, LB Steppan, JA Brauner, JA Deyo, MC Henderson, ... Toxicology and applied pharmacology 105 (1), 26-36, 1990 | 155 | 1990 |
Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing NB Marshall, SK Oda, CA London, HM Moulton, PL Iversen, NI Kerkvliet, ... Journal of immunological methods 325 (1-2), 114-126, 2007 | 145 | 2007 |
TCDD, FICZ, and Other High Affinity AhR Ligands Dose-Dependently Determine the Fate of CD4+ T Cell Differentiation AK Ehrlich, JM Pennington, WH Bisson, SK Kolluri, NI Kerkvliet Toxicological sciences 161 (2), 310-320, 2018 | 143 | 2018 |
The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor EF O'Donnell, KS Saili, DC Koch, PR Kopparapu, D Farrer, WH Bisson, ... PloS one 5 (10), e13128, 2010 | 136 | 2010 |
Inhibition of TC-1 cytokine production, effector cytotoxic T lymphocyte development and alloantibody production by 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin. NI Kerkvliet, L Baecher-Steppan, DM Shepherd, JA Oughton, ... Journal of immunology (Baltimore, Md.: 1950) 157 (6), 2310-2319, 1996 | 123 | 1996 |
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin affects the number and function of murine splenic dendritic cells and their expression of accessory molecules BA Vorderstrasse, NI Kerkvliet Toxicology and applied pharmacology 171 (2), 117-125, 2001 | 116 | 2001 |
Functional characterization and gene expression analysis of CD4+ CD25+ regulatory T cells generated in mice treated with 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin NB Marshall, WR Vorachek, LB Steppan, DV Mourich, NI Kerkvliet The Journal of Immunology 181 (4), 2382-2391, 2008 | 114 | 2008 |