Single-cell developmental classification of B cell precursor acute lymphoblastic leukemia at diagnosis reveals predictors of relapse Z Good, J Sarno, A Jager, N Samusik, N Aghaeepour, EF Simonds, ... Nature medicine 24 (4), 474-483, 2018 | 122 | 2018 |
The histone deacetylase inhibitor givinostat (ITF2357) exhibits potent anti-tumor activity against CRLF2-rearranged BCP-ALL AM Savino, J Sarno, L Trentin, M Vieri, G Fazio, M Bardini, C Bugarin, ... Leukemia 31 (11), 2365-2375, 2017 | 46 | 2017 |
Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia C Bugarin, J Sarno, C Palmi, AM Savino, G te Kronnie, M Dworzak, ... Haematologica 100 (6), e229, 2015 | 36 | 2015 |
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia I Geron, AM Savino, H Fishman, N Tal, J Brown, VA Turati, C James, ... Nature communications 13 (1), 659, 2022 | 20 | 2022 |
SRC/ABL inhibition disrupts CRLF2-driven signaling to induce cell death in B-cell acute lymphoblastic leukemia J Sarno, AM Savino, C Buracchi, C Palmi, S Pinto, C Bugarin, A Jager, ... Oncotarget 9 (33), 22872, 2018 | 16 | 2018 |
CytofIn enables integrated analysis of public mass cytometry datasets using generalized anchors YC Lo, TJ Keyes, A Jager, J Sarno, P Domizi, R Majeti, KM Sakamoto, ... Nature Communications 13 (1), 934, 2022 | 10 | 2022 |
Dasatinib overcomes glucocorticoid resistance in B-cell acute lymphoblastic leukemia J Sarno, P Domizi, Y Liu, M Merchant, CB Pedersen, D Jedoui, A Jager, ... Nature Communications 14 (1), 2935, 2023 | 6 | 2023 |
Mass Cytometry of Hematopoietic Cells A Jager, J Sarno, KL Davis Leukemia Stem Cells, 65-76, 2021 | 6 | 2021 |
Ikaros mediates antigen escape following CD19 CAR T cell therapy in r/r B-ALL P Domizi, J Sarno, A Jager, R Baskar, WD Reynolds, B Sahaf, S Bendall, ... Blood 138, 613, 2021 | 5 | 2021 |
Peripheral blood cells from children with RASopathies show enhanced spontaneous colonies growth in vitro and hyperactive RAS signaling G Gaipa, C Bugarin, P Cianci, J Sarno, P Bonaccorso, A Biondi, ... Blood Cancer Journal 5 (7), e324-e324, 2015 | 5 | 2015 |
An instructive role for IL7RA in the development of human B-cell precursor leukemia I Geron, AM Savino, N Tal, J Brown, V Turati, C James, J Sarno, YN Lee, ... BioRxiv, 2020.01. 27.919951, 2020 | 4 | 2020 |
Genome editing–induced t (4; 11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-AFF1 fusion F Pan, J Sarno, J Jeong, X Yang, A Jager, TA Gruber, KL Davis, ... The Journal of Clinical Investigation 134 (1), 2024 | 2 | 2024 |
Prediction of patients at risk of CD19Neg relapse following CD19-Directed CAR T cell therapy in B cell precursor acute lymphoblastic leukemia P Domizi, A Jager, J Sarno, CG Mullighan, S Grupp, E Sotillo, DM Barrett, ... Blood 134, 749, 2019 | 2 | 2019 |
Single-cell mass cytometry and machine learning predict relapse in childhood leukemia J Sarno, KL Davis Molecular & Cellular Oncology 5 (5), e1472057, 2018 | 2 | 2018 |
Glucocorticoids exert a dual role in B-cell acute lymphoblastic leukemia: apoptosis and differentiation of early B-cell populations J Sarno, C Pedersen, A Jager, T Burns, G Gaipa, G Nolan, A Bava, ... Experimental Hematology 64, S100, 2018 | 2 | 2018 |
Role of the histone deacetylase inhibitor givinostat (ITF2357) in treatment of CRLF2 rearranged acute lymphoblastic leukemia AM Savino, J Sarno, L Trentin, M Vieri, G Fazio, M Bardini, C Bugarin, ... Blood 126 (23), 2534, 2015 | 2 | 2015 |
CNS-wide repopulation by hematopoietic-derived microglia-like cells corrects progranulin deficiency in mice P Colella, R Sayana, MV Suarez-Nieto, J Sarno, K Nyame, J Xiong, ... Nature Communications 15 (1), 5654, 2024 | 1 | 2024 |
CNS Repopulation by Hematopoietic-Derived Microglia-Like Cells Corrects Progranulin deficiency P Colella, R Sayana, MV Suarez-Nieto, J Sarno, K Nyame, J Xiong, ... Research Square, 2023 | 1 | 2023 |
Single-Cell Proteomic Analysis Defines Metabolic Heterogeneity in Response to Venetoclax in AML L Stuani, A Jager, A Sahal, A Koladiya, J Sarno, P Domizi, Y Liu, ... Blood 140 (Supplement 1), 1028-1029, 2022 | 1 | 2022 |
MMIL: A novel algorithm for disease associated cell type discovery E Craig, T Keyes, J Sarno, M Zaslavsky, G Nolan, K Davis, T Hastie, ... arXiv preprint arXiv:2406.08322, 2024 | | 2024 |