CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts C Ginestier, S Liu, ME Diebel, H Korkaya, M Luo, M Brown, J Wicinski, ... The Journal of clinical investigation 120 (2), 485-497, 2010 | 918 | 2010 |
Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia SJ Conley, E Gheordunescu, P Kakarala, B Newman, H Korkaya, ... Proceedings of the National Academy of Sciences 109 (8), 2784-2789, 2012 | 743 | 2012 |
HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion H Korkaya, A Paulson, F Iovino, MS Wicha Oncogene 27 (47), 6120-6130, 2008 | 729 | 2008 |
Breast cancer stem cells, cytokine networks, and the tumor microenvironment H Korkaya, S Liu, MS Wicha The Journal of clinical investigation 121 (10), 3804-3809, 2011 | 726 | 2011 |
Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks S Liu, C Ginestier, SJ Ou, SG Clouthier, SH Patel, F Monville, H Korkaya, ... Cancer research 71 (2), 614-624, 2011 | 718 | 2011 |
Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells Y Li, T Zhang, H Korkaya, S Liu, HF Lee, B Newman, Y Yu, SG Clouthier, ... Clinical Cancer Research 16 (9), 2580-2590, 2010 | 664 | 2010 |
Regulation of mammary stem/progenitor cells by PTEN/Akt/β-catenin signaling H Korkaya, A Paulson, E Charafe-Jauffret, C Ginestier, M Brown, ... PLoS biology 7 (6), e1000121, 2009 | 639 | 2009 |
Targeting breast stem cells with the cancer preventive compounds curcumin and piperine M Kakarala, DE Brenner, H Korkaya, C Cheng, K Tazi, C Ginestier, S Liu, ... Breast cancer research and treatment 122, 777-785, 2010 | 586 | 2010 |
Activation of an IL6 inflammatory loop mediates trastuzumab resistance in HER2+ breast cancer by expanding the cancer stem cell population H Korkaya, G Kim, A Davis, F Malik, NL Henry, S Ithimakin, AA Quraishi, ... Molecular cell 47 (4), 570-584, 2012 | 579 | 2012 |
The interplay between Src family kinases and receptor tyrosine kinases PA Bromann, H Korkaya, SA Courtneidge Oncogene 23 (48), 7957-7968, 2004 | 573 | 2004 |
Regulation of cancer stem cells by cytokine networks: attacking cancer's inflammatory roots H Korkaya, S Liu, MS Wicha Clinical Cancer Research 17 (19), 6125-6129, 2011 | 361 | 2011 |
Monocytic and granulocytic myeloid derived suppressor cells differentially regulate spatiotemporal tumour plasticity during metastatic cascade M Ouzounova, E Lee, R Piranlioglu, A El Andaloussi, R Kolhe, ... Nature communications 8 (1), 14979, 2017 | 346 | 2017 |
HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab S Ithimakin, KC Day, F Malik, Q Zen, SJ Dawsey, TF Bersano-Begey, ... Cancer research 73 (5), 1635-1646, 2013 | 275 | 2013 |
Notch pathway activity identifies cells with cancer stem cell–like properties and correlates with worse survival in lung adenocarcinoma KA Hassan, L Wang, H Korkaya, G Chen, I Maillard, DG Beer, ... Clinical cancer research 19 (8), 1972-1980, 2013 | 224 | 2013 |
The ORF3 protein of hepatitis E virus binds to Src homology 3 domains and activates MAPK H Korkaya, S Jameel, D Gupta, S Tyagi, R Kumar, M Zafrullah, ... Journal of Biological Chemistry 276 (45), 42389-42400, 2001 | 200 | 2001 |
MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells S Liu, SH Patel, C Ginestier, I Ibarra, R Martin-Trevino, S Bai, ... PLoS genetics 8 (6), e1002751, 2012 | 188 | 2012 |
The phosphorylated form of the ORF3 protein of hepatitis E virus interacts with its non-glycosylated form of the major capsid protein, ORF2 S Tyagi, H Korkaya, M Zafrullah, S Jameel, SK Lal Journal of Biological Chemistry 277 (25), 22759-22767, 2002 | 183 | 2002 |
Selective targeting of cancer stem cells: a new concept in cancer therapeutics H Korkaya, MS Wicha BioDrugs 21, 299-310, 2007 | 172 | 2007 |
HER-2, notch, and breast cancer stem cells: targeting an axis of evil H Korkaya, MS Wicha Clinical Cancer Research 15 (6), 1845-1847, 2009 | 158 | 2009 |
Notch reporter activity in breast cancer cell lines identifies a subset of cells with stem cell activity RC D'Angelo, M Ouzounova, A Davis, D Choi, SM Tchuenkam, G Kim, ... Molecular cancer therapeutics 14 (3), 779-787, 2015 | 144 | 2015 |