Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5576 | 2018 |
ER stress triggers apoptosis by activating BH3-only protein Bim H Puthalakath, LA O'Reilly, P Gunn, L Lee, PN Kelly, ND Huntington, ... Cell 129 (7), 1337-1349, 2007 | 1675 | 2007 |
The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex H Puthalakath, DCS Huang, LA O’Reilly, SM King, A Strasser Molecular cell 3 (3), 287-296, 1999 | 1471 | 1999 |
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1161 | 2015 |
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes P Bouillet, JF Purton, DI Godfrey, LC Zhang, L Coultas, H Puthalakath, ... Nature 415 (6874), 922-926, 2002 | 999 | 2002 |
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins. H Puthalakath, A Strasser Cell Death and Differentiation 9 (5), 505-512, 2002 | 947 | 2002 |
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes L Galluzzi, SA Aaronson, J Abrams, ES Alnemri, DW Andrews, ... Cell Death & Differentiation 16 (8), 1093-1107, 2009 | 838 | 2009 |
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis H Puthalakath, A Villunger, LA O'Reilly, JG Beaumont, L Coultas, ... Science 293 (5536), 1829-1832, 2001 | 832 | 2001 |
To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3: groove interactions G Dewson, T Kratina, HW Sim, H Puthalakath, JM Adams, PM Colman, ... Molecular cell 30 (3), 369-380, 2008 | 393 | 2008 |
Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics MS Cragg, J Kuroda, H Puthalakath, DCS Huang, A Strasser PLoS medicine 4 (10), e316, 2007 | 387 | 2007 |
Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic J Kuroda, H Puthalakath, MS Cragg, PN Kelly, P Bouillet, DCS Huang, ... Proceedings of the National Academy of Sciences 103 (40), 14907-14912, 2006 | 380 | 2006 |
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation–induced apoptosis and deletion of autoreactive B cells A Enders, P Bouillet, H Puthalakath, Y Xu, DM Tarlinton, A Strasser The Journal of experimental medicine 198 (7), 1119-1126, 2003 | 366 | 2003 |
Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1 ND Huntington, H Puthalakath, P Gunn, E Naik, EM Michalak, MJ Smyth, ... Nature immunology 8 (8), 856-863, 2007 | 297 | 2007 |
Bcl‐2 family proteins: the sentinels of the mitochondrial apoptosis pathway WWL Wong, H Puthalakath IUBMB life 60 (6), 390-397, 2008 | 264 | 2008 |
Sepsis: inflammation is a necessary evil C Nedeva, J Menassa, H Puthalakath Frontiers in cell and developmental biology 7, 108, 2019 | 250 | 2019 |
Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate C Navarro, H Puthalakath, JM Adams, A Strasser, R Lehmann Nature cell biology 6 (5), 427-435, 2004 | 223 | 2004 |
The Role of Bim, a Proapoptotic BH3‐Only Member of the Bcl‐2 Family, in Cell‐Death Control A Strasser, H Puthalakath, P Bouillet, DCS Huang, L O'CONNOR, ... Annals of the New York Academy of Sciences 917 (1), 541-548, 2000 | 207 | 2000 |
A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation EF Lee, PE Czabotar, MF Van Delft, EM Michalak, MJ Boyle, SN Willis, ... The Journal of cell biology 180 (2), 341-355, 2008 | 188 | 2008 |
Fatal hepatitis mediated by tumor necrosis factor TNFα requires caspase-8 and involves the BH3-only proteins Bid and Bim T Kaufmann, PJ Jost, M Pellegrini, H Puthalakath, R Gugasyan, ... Immunity 30 (1), 56-66, 2009 | 161 | 2009 |
Therapeutic molecules S Cory, J Adams, DCS Huang, L O'connor, A Strasser, H Puthalakath, ... US Patent 7,064,193, 2006 | 127 | 2006 |