Impaired IFN-α production by plasmacytoid dendritic cells favors regulatory T-cell expansion that may contribute to breast cancer progression V Sisirak, J Faget, M Gobert, N Goutagny, N Vey, I Treilleux, ... Cancer research 72 (20), 5188-5197, 2012 | 343 | 2012 |
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils C Engblom, C Pfirschke, R Zilionis, J Da Silva Martins, SA Bos, G Courties, ... Science 358 (6367), eaal5081, 2017 | 337 | 2017 |
Quantitative and functional alterations of plasmacytoid dendritic cells contribute to immune tolerance in ovarian cancer SI Labidi-Galy, V Sisirak, P Meeus, M Gobert, I Treilleux, A Bajard, ... Cancer research 71 (16), 5423-5434, 2011 | 240 | 2011 |
ICOS-Ligand Expression on Plasmacytoid Dendritic Cells Supports Breast Cancer Progression by Promoting the Accumulation of Immunosuppressive CD4+ T Cells J Faget, N Bendriss-Vermare, M Gobert, I Durand, D Olive, C Biota, ... Cancer research 72 (23), 6130-6141, 2012 | 233 | 2012 |
Durable and controlled depletion of neutrophils in mice G Boivin, J Faget, PB Ancey, A Gkasti, J Mussard, C Engblom, C Pfirschke, ... Nature communications 11 (1), 2762, 2020 | 208 | 2020 |
Neutrophils and snail orchestrate the establishment of a pro-tumor microenvironment in lung cancer J Faget, S Groeneveld, G Boivin, M Sankar, N Zangger, M Garcia, N Guex, ... Cell reports 21 (11), 3190-3204, 2017 | 187 | 2017 |
Early detection of tumor cells by innate immune cells leads to Treg recruitment through CCL22 production by tumor cells J Faget, C Biota, T Bachelot, M Gobert, I Treilleux, N Goutagny, I Durand, ... Cancer research 71 (19), 6143-6152, 2011 | 148 | 2011 |
ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+ T cells by plasmacytoid dendritic cells J Faget, V Sisirak, JY Blay, C Caux, N Bendriss-Vermare, ... Oncoimmunology 2 (3), e23185, 2013 | 120 | 2013 |
Targeting regulatory T cells C Ménétrier-Caux, T Curiel, J Faget, M Manuel, C Caux, W Zou Targeted oncology 7, 15-28, 2012 | 96 | 2012 |
Autocrine Adenosine Regulates Tumor Polyfunctional CD73+CD4+ Effector T Cells Devoid of Immune Checkpoints N Gourdin, M Bossennec, C Rodriguez, S Vigano, C Machon, C Jandus, ... Cancer research 78 (13), 3604-3618, 2018 | 67 | 2018 |
Neutrophils in the era of immune checkpoint blockade J Faget, S Peters, X Quantin, E Meylan, N Bonnefoy Journal for ImmunoTherapy of Cancer 9 (7), 2021 | 65 | 2021 |
Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+ regulatory T cells and are associated with poor prognosis in breast … V Sisirak, J Faget, N Vey, JY Blay, C Ménétrier-Caux, C Caux, ... Oncoimmunology 2 (1), e22338, 2013 | 64 | 2013 |
Radiation-induced immunity and toxicities: the versatility of the cGAS-STING pathway J Constanzo, J Faget, C Ursino, C Badie, JP Pouget Frontiers in immunology 12, 680503, 2021 | 42 | 2021 |
Cellular composition and contribution of tertiary lymphoid structures to tumor immune infiltration and modulation by radiation therapy G Boivin, P Kalambaden, J Faget, S Rusakiewicz, P Montay-Gruel, ... Frontiers in oncology 8, 256, 2018 | 41 | 2018 |
Antibodies directed against ICOS and uses thereof J Faget, C Caux, C Menetrier-Caux, J Nunes, D Olive US Patent 9,376,493, 2016 | 32 | 2016 |
Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment C Menetrier-Caux, J Faget, C Biota, M Gobert, JY Blay, C Caux Oncoimmunology 1 (5), 759-761, 2012 | 29 | 2012 |
RANKL signaling sustains primary tumor growth in genetically engineered mouse models of lung adenocarcinoma J Faget, C Contat, N Zangger, S Peters, E Meylan Journal of Thoracic Oncology 13 (3), 387-398, 2018 | 24 | 2018 |
Efficient and specific Ly6G+ cell depletion: A change in the current practices toward more relevant functional analyses of neutrophils J Faget, G Boivin, PB Ancey, A Gkasti, J Mussard, C Engblom, C Pfirschke, ... BioRxiv, 498881, 2018 | 23 | 2018 |
Antibodies directed against ICOS and uses thereof J Faget, C Caux, C Menetrier-Caux, J Nunes, D Olive US Patent 9,676,852, 2017 | 20 | 2017 |
Single-cell high-dimensional imaging mass cytometry: one step beyond in oncology Y Glasson, LA Chépeaux, AS Dumé, V Lafont, J Faget, N Bonnefoy, ... Seminars in Immunopathology 45 (1), 17-28, 2023 | 16 | 2023 |