Structure and signalling in the IL-17 receptor family SL Gaffen Nature Reviews Immunology 9 (8), 556-567, 2009 | 1777 | 2009 |
IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge SA Khader, GK Bell, JE Pearl, JJ Fountain, J Rangel-Moreno, GE Cilley, ... Nature immunology 8 (4), 369-377, 2007 | 1741 | 2007 |
The IL-23–IL-17 immune axis: from mechanisms to therapeutic testing SL Gaffen, R Jain, AV Garg, DJ Cua Nature reviews immunology 14 (9), 585-600, 2014 | 1564 | 2014 |
Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis HR Conti, F Shen, N Nayyar, E Stocum, JN Sun, MJ Lindemann, AW Ho, ... Journal of Experimental Medicine 206 (2), 299-311, 2009 | 1172 | 2009 |
Interleukin‐17 and its target genes: mechanisms of interleukin‐17 function in disease RM Onishi, SL Gaffen Immunology 129 (3), 311-321, 2010 | 1156 | 2010 |
The IL-17 family of cytokines in health and disease MJ McGeachy, DJ Cua, SL Gaffen Immunity 50 (4), 892-906, 2019 | 1000 | 2019 |
IL-17 signaling: the yin and the yang N Amatya, AV Garg, SL Gaffen Trends in immunology 38 (5), 310-322, 2017 | 645 | 2017 |
Overview of interleukin-2 function, production and clinical applications SL Gaffen, KD Liu Cytokine 28 (3), 109-123, 2004 | 640 | 2004 |
1,25-Dihydroxyvitamin D3 Ameliorates Th17 Autoimmunity via Transcriptional Modulation of Interleukin-17A S Joshi, LC Pantalena, XK Liu, SL Gaffen, H Liu, C Rohowsky-Kochan, ... Molecular and cellular biology 31 (17), 3653-3669, 2011 | 589 | 2011 |
Th17 cells at the crossroads of innate and adaptive immunity against infectious diseases at the mucosa SA Khader, SL Gaffen, JK Kolls Mucosal immunology 2 (5), 403-411, 2009 | 552 | 2009 |
An overview of IL-17 function and signaling SL Gaffen Cytokine 43 (3), 402-407, 2008 | 512 | 2008 |
An essential role for IL-17 in preventing pathogen-initiated bone destruction: recruitment of neutrophils to inflamed bone requires IL-17 receptor–dependent signals JJ Yu, MJ Ruddy, GC Wong, C Sfintescu, PJ Baker, JB Smith, RT Evans, ... Blood 109 (9), 3794-3802, 2007 | 463 | 2007 |
Functional cooperation between interleukin-17 and tumor necrosis factor-α is mediated by CCAAT/enhancer-binding protein family members MJ Ruddy, GC Wong, XK Liu, H Yamamoto, S Kasayama, KL Kirkwood, ... Journal of Biological Chemistry 279 (4), 2559-2567, 2004 | 459 | 2004 |
A new inflammatory cytokine on the block: re-thinking periodontal disease and the Th1/Th2 paradigm in the context of Th17 cells and IL-17 SL Gaffen, G Hajishengallis Journal of dental research 87 (9), 817-828, 2008 | 457 | 2008 |
Th17 cells in immunity to Candida albicans N Hernández-Santos, SL Gaffen Cell host & microbe 11 (5), 425-435, 2012 | 387 | 2012 |
Recent advances in the IL-17 cytokine family SL Gaffen Current opinion in immunology 23 (5), 613-619, 2011 | 383 | 2011 |
Structure–function relationships in the IL-17 receptor: implications for signal transduction and therapy F Shen, SL Gaffen Cytokine 41 (2), 92-104, 2008 | 378 | 2008 |
Identification of common transcriptional regulatory elements in interleukin-17 target genes F Shen, Z Hu, J Goswami, SL Gaffen Journal of Biological Chemistry 281 (34), 24138-24148, 2006 | 363 | 2006 |
Cytokines link osteoblasts and inflammation: microarray analysis of interleukin-17-and TNF-α-induced genes in bone cells F Shen, MJ Ruddy, P Plamondon, SL Gaffen Journal of leukocyte biology 77 (3), 388-399, 2005 | 359 | 2005 |
IL-17 receptor–based signaling and implications for disease X Li, R Bechara, J Zhao, MJ McGeachy, SL Gaffen Nature immunology 20 (12), 1594-1602, 2019 | 351 | 2019 |