Rapid and scalable characterization of CRISPR technologies using an E. coli cell-free transcription-translation system R Marshall, CS Maxwell, SP Collins, T Jacobsen, ML Luo, MB Begemann, ... Molecular cell 69 (1), 146-157. e3, 2018 | 212 | 2018 |
Short DNA containing χ sites enhances DNA stability and gene expression in E. coli cell‐free transcription–translation systems R Marshall, CS Maxwell, SP Collins, CL Beisel, V Noireaux Biotechnology and bioengineering 114 (9), 2137-2141, 2017 | 101 | 2017 |
A genetically encoded anti-CRISPR protein constrains gene drive spread and prevents population suppression C Taxiarchi, A Beaghton, NI Don, K Kyrou, M Gribble, D Shittu, SP Collins, ... Nature Communications 12 (1), 3977, 2021 | 43 | 2021 |
In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii D Durmusoglu, IS Al’Abri, SP Collins, J Cheng, A Eroglu, CL Beisel, ... ACS synthetic biology 10 (5), 1039-1052, 2021 | 37 | 2021 |
Global intersection of long non-coding RNAs with processed and unprocessed pseudogenes in the human genome MJ Milligan, E Harvey, A Yu, AL Morgan, DL Smith, E Zhang, J Berengut, ... Frontiers in genetics 7, 26, 2016 | 35 | 2016 |
An educational module to explore CRISPR technologies with a cell-free transcription-translation system D Collias, R Marshall, SP Collins, CL Beisel, V Noireaux Synthetic Biology 4 (1), ysz005, 2019 | 33 | 2019 |
Sequence-independent RNA sensing and DNA targeting by a split domain CRISPR–Cas12a gRNA switch SP Collins, W Rostain, C Liao, CL Beisel Nucleic Acids Research 49 (5), 2985-2999, 2021 | 31 | 2021 |
An enhanced assay to characterize anti-CRISPR proteins using a cell-free transcription-translation system KG Wandera, SP Collins, F Wimmer, R Marshall, V Noireaux, CL Beisel Methods 172, 42-50, 2020 | 27 | 2020 |
A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes Cas9 D Collias, RT Leenay, RA Slotkowski, Z Zuo, SP Collins, BA McGirr, J Liu, ... Science advances 6 (29), eabb4054, 2020 | 23 | 2020 |
A target expression threshold dictates invader defense and prevents autoimmunity by CRISPR-Cas13 E Vialetto, Y Yu, SP Collins, KG Wandera, L Barquist, CL Beisel Cell host & microbe 30 (8), 1151-1162. e6, 2022 | 14 | 2022 |
A positive, growth-based PAM screen identifies noncanonical motifs recognized by the S. pyogenes D Collias, RT Leenay, RA Slotkowski, Z Zuo, SP Collins, BA McGirr, J Liu, ... Cas9. Sci. Adv 6, 2020 | 6 | 2020 |
Your base editor might be flirting with single (stranded) DNA: faithful on-target CRISPR base editing without promiscuous deamination SP Collins, CL Beisel Molecular Cell 79 (5), 703-704, 2020 | 2 | 2020 |
Establishing Probiotic Saccharomyces boulardii as a Model Organism for Synthesis and Delivery of Biomolecules D Durmusoglu, I Al’Abri, SP Collins, C Beisel, N Crook bioRxiv, 2020.01. 22.915389, 2020 | 2 | 2020 |
A target expression threshold dictates invader defense and autoimmunity by CRISPR-Cas13 E Vialetto, Y Yu, SP Collins, KG Wandera, L Barquist, CL Beisel BioRxiv, 2021.11. 23.469693, 2021 | 1 | 2021 |
Site-specific genome modification technology CL Beisel, SP Collins US Patent App. 18/546,378, 2024 | | 2024 |
Expanding the flexibility of base editing for high-throughput genetic screens in bacteria S Gawlitt, SP Collins, Y Yu, SA Blackman, L Barquist, CL Beisel Nucleic Acids Research 52 (7), 4079-4097, 2024 | | 2024 |
Interrogating two extensively self-targeting Type I CRISPR-Cas systems in Xanthomonas albilineans reveals distinct anti-CRISPR proteins that block DNA … F Wimmer, F Englert, KG Wandera, OS Alkhnbashi, SP Collins, ... Nucleic Acids Research 52 (2), 769-783, 2024 | | 2024 |
Compositions, methods, and systems for genome editing technology CL Beisel, S Collins US Patent App. 17/905,934, 2023 | | 2023 |
Controlling Outcomes in Crispr-Based Genome Editing SP Collins North Carolina State University, 2022 | | 2022 |