Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle L Caputi, J Franke, SC Farrow, K Chung, RME Payne, TD Nguyen, ... Science 360 (6394), 1235-1239, 2018 | 323 | 2018 |
Genomics‐Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic Burkholderia Species J Franke, K Ishida, C Hertweck Angewandte Chemie 124 (46), 11779-11783, 2012 | 130 | 2012 |
Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis M Baunach, J Franke, C Hertweck Angewandte Chemie International Edition 54 (9), 2604-2626, 2015 | 124 | 2015 |
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate EC Tatsis, I Carqueijeiro, T Dugé de Bernonville, J Franke, TTT Dang, ... Nature communications 8 (1), 316, 2017 | 117 | 2017 |
Biomimetic thioesters as probes for enzymatic assembly lines: synthesis, applications, and challenges J Franke, C Hertweck Cell Chemical Biology 23 (10), 1179-1192, 2016 | 95 | 2016 |
Gene Discovery in Gelsemium Highlights Conserved Gene Clusters in Monoterpene Indole Alkaloid Biosynthesis J Franke, J Kim, JP Hamilton, D Zhao, GM Pham, K Wiegert‐Rininger, ... ChemBioChem 20 (1), 83-87, 2019 | 86 | 2019 |
Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes TTT Dang, J Franke, IST Carqueijeiro, C Langley, V Courdavault, ... Nature chemical biology 14 (8), 760-763, 2018 | 61 | 2018 |
Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis. J Franke, K Ishida, M Ishida‐Ito, C Hertweck Angewandte Chemie 125 (32), 2013 | 55 | 2013 |
A pair of bacterial siderophores releases and traps an intercellular signal molecule: An unusual case of natural nitrone bioconjugation F Trottmann, J Franke, K Ishida, M García‐Altares, C Hertweck Angewandte Chemie International Edition 58 (1), 200-204, 2019 | 40 | 2019 |
Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina TTT Dang, J Franke, E Tatsis, SE O'Connor Angewandte Chemie 129 (32), 9568-9572, 2017 | 39 | 2017 |
Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species F Trottmann, J Franke, I Richter, K Ishida, M Cyrulies, HM Dahse, ... Angewandte Chemie International Edition 58 (40), 14129-14133, 2019 | 34 | 2019 |
Biosynthetic code for divergolide assembly in a bacterial mangrove endophyte Z Xu, M Baunach, L Ding, H Peng, J Franke, C Hertweck ChemBioChem 15 (9), 1274-1279, 2014 | 34 | 2014 |
Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids L Caputi, J Franke, K Bussey, SC Farrow, IJC Vieira, CEM Stevenson, ... Nature chemical biology 16 (4), 383-386, 2020 | 32 | 2020 |
Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor F Trottmann, K Ishida, J Franke, A Stanišić, M Ishida‐Ito, H Kries, ... Angewandte Chemie 132 (32), 13613-13617, 2020 | 31 | 2020 |
Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteria J Franke, K Ishida, C Hertweck Chemistry–A European Journal 21 (22), 8010-8014, 2015 | 29 | 2015 |
Dugé de Bernonville T, Ameyaw B, Jones DM, Vieira IJC, Courdavault V, O’Connor SE (2018) Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar … L Caputi, J Franke, SC Farrow, K Chung, RME Payne, TD Nguyen, ... Science 360 (6394), 1235-1239, 0 | 28 | |
Evolution of siderophore pathways in human pathogenic bacteria J Franke, K Ishida, C Hertweck Journal of the American Chemical Society 136 (15), 5599-5602, 2014 | 26 | 2014 |
Divergolide congeners illuminate alternative reaction channels for ansamycin diversification L Ding, J Franke, C Hertweck Organic & Biomolecular Chemistry 13 (6), 1618-1623, 2015 | 25 | 2015 |
Terpenoid‐Biosynthese abseits bekannter Wege: unkonventionelle Cyclasen und ihre Bedeutung für die biomimetische Synthese M Baunach, J Franke, C Hertweck Angewandte Chemie 127 (9), 2640-2664, 2015 | 17 | 2015 |
Cytochrome P450 monooxygenase-mediated tailoring of triterpenoids and steroids in plants K Malhotra, J Franke Beilstein Journal of Organic Chemistry 18 (1), 1289-1310, 2022 | 14 | 2022 |