Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways RM Essam, LA Ahmed, RM Abdelsalam, AS El-Khatib Life sciences 222, 245-254, 2019 | 44 | 2019 |
Lutein exerts its cardioprotective effect against the experimental model of isoprenaline‐induced myocardial infarction via MIAT/miR‐200a/Nrf2/TXINP pathway M Abdelmonem, SM Ibrahim, RM Essam, HAA Amin, MA Abd‐Elmawla Journal of Biochemical and Molecular Toxicology 35 (11), e22899, 2021 | 12 | 2021 |
A comparative study of the antihypertensive and cardioprotective potentials of hot and cold aqueous extracts of Hibiscus sabdariffa L. in relation to their metabolic profiles MA Salem, SM Ezzat, KA Ahmed, S Alseekh, AR Fernie, RM Essam Frontiers in Pharmacology 13, 840478, 2022 | 11 | 2022 |
Implication of Wnt/GSK-3β/β-catenin signaling in the pathogenesis of mood disturbances associated with hyperthyroidism in rats: potential therapeutic effect of naringin MA Abd-Elmawla, RM Essam, KA Ahmed, M Abdelmonem ACS Chemical Neuroscience 14 (11), 2035-2048, 2023 | 9 | 2023 |
Donepezil halts acetic acid-induced experimental colitis in rats and its associated cognitive impairment through regulating inflammatory/oxidative/apoptotic cascades: an add-on … EM Elbaz, RM Essam, KA Ahmed, MH Safwat International Immunopharmacology 116, 109841, 2023 | 9 | 2023 |
p-CREB and p-DARPP-32 orchestrating the modulatory role of cAMP/PKA signaling pathway enhanced by Roflumilast in rotenone-induced Parkinson's disease in rats RM Essam, EA Kandil Chemico-Biological Interactions 372, 110366, 2023 | 4 | 2023 |
Lactoferrin averts neurological and behavioral impairments of thioacetamide-induced hepatic encephalopathy in rats via modulating HGMB1/TLR-4/MyD88/Nrf2 pathway RM Essam, MA Saadawy, M Gamal, RM Abdelsalam, AE El-Sahar Neuropharmacology 236, 109575, 2023 | 3 | 2023 |
Targeting HMGB1/PI3K/Akt and NF-κB/Nrf-2 signaling pathways by vildagliptin mitigates testosterone-induced benign prostate hyperplasia in rats AE El-Sahar, N Bekhit, NM Eissa, RM Abdelsalam, RM Essam Life Sciences 322, 121645, 2023 | 3 | 2023 |
The citrus flavonoid “Nobiletin” impedes STZ-induced Alzheimer’s disease in a mouse model through regulating autophagy mastered by SIRT1/FoxO3a mechanism SA El-Maraghy, A Reda, RM Essam, MA Kortam Inflammopharmacology 31 (5), 2701-2717, 2023 | 1 | 2023 |
Unleashing lactoferrin's antidepressant potential through the PI3K/Akt/mTOR pathway in chronic restraint stress rats HH Ahmed, RM Essam, MF El-Yamany, KA Ahmed, AE El-Sahar Food & Function 14 (20), 9265-9278, 2023 | 1 | 2023 |
Novel fast dissolving freeze dried sublingual baicalin tablets for enhanced hepatoprotective effect: in-vitro characterization, cell viability, and in-vivo evaluation FN Abdelrazek, RA Shalaby, SA Fahim, RM Essam, SE Anis, YM Attia, ... Pharmaceutical Development and Technology, 1-12, 2024 | | 2024 |
The preferential effect of Clemastine on F3/Contactin-1/Notch-1 compared to Jagged-1/Notch-1 justifies its remyelinating effect in an experimental model of multiple sclerosis … SM Ibrahim, AS Kamel, KA Ahmed, RA Mohammed, RM Essam International Immunopharmacology 128, 111481, 2024 | | 2024 |
Therapeutic effects of combining curcumin and swimming in osteoarthritis using a rat model MM Saber, MM Mahmoud, HM Amin, RM Essam Biomedicine & Pharmacotherapy 166, 115309, 2023 | | 2023 |
IRats: Intelligent system for rat behavior analysis A Zaky, MM Saber, RM Essam, A Atia 2022 2nd International Mobile, Intelligent, and Ubiquitous Computing …, 2022 | | 2022 |