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Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6 C Vance, B Rogelj, T Hortobágyi, KJ De Vos, AL Nishimura, J Sreedharan, ... Science 323 (5918), 1208-1211, 2009 | 3016 | 2009 |
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43 JR Tollervey, T Curk, B Rogelj, M Briese, M Cereda, M Kayikci, J König, ... Nature neuroscience 14 (4), 452-458, 2011 | 1234 | 2011 |
Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 604 | 2016 |
p62 positive, TDP-43 negative, neuronal cytoplasmic and intranuclear inclusions in the cerebellum and hippocampus define the pathology of C9orf72-linked FTLD … S Al-Sarraj, A King, C Troakes, B Smith, S Maekawa, I Bodi, B Rogelj, ... Acta neuropathologica 122, 691-702, 2011 | 564 | 2011 |
Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic YB Lee, HJ Chen, JN Peres, J Gomez-Deza, J Attig, M Štalekar, ... Cell reports 5 (5), 1178-1186, 2013 | 558 | 2013 |
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Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age-and dose-dependent fashion JC Mitchell, P McGoldrick, C Vance, T Hortobagyi, J Sreedharan, B Rogelj, ... Acta neuropathologica 125, 273-288, 2013 | 319 | 2013 |
Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology W Van Rheenen, RAA Van Der Spek, MK Bakker, JJFA Van Vugt, PJ Hop, ... Nature genetics 53 (12), 1636-1648, 2021 | 312 | 2021 |
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules C Vance, EL Scotter, AL Nishimura, C Troakes, JC Mitchell, C Kathe, ... Human molecular genetics 22 (13), 2676-2688, 2013 | 290 | 2013 |
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The C9ORF72 expansion mutation is a common cause of ALS+/− FTD in Europe and has a single founder BN Smith, S Newhouse, A Shatunov, C Vance, S Topp, L Johnson, ... European Journal of Human Genetics 21 (1), 102-108, 2013 | 256 | 2013 |
Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration AL Nishimura, V Župunski, C Troakes, C Kathe, P Fratta, M Howell, ... Brain 133 (6), 1763-1771, 2010 | 225 | 2010 |
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The X11 proteins, Aβ production and Alzheimer's disease CCJ Miller, DM McLoughlin, KF Lau, ME Tennant, B Rogelj Trends in neurosciences 29 (5), 280-285, 2006 | 126 | 2006 |
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Expression of sea anemone equistatin in potato. Effects of plant proteases on heterologous protein production NS Outchkourov, B Rogelj, B Strukelj, MA Jongsma Plant physiology 133 (1), 379-390, 2003 | 111 | 2003 |
Cross-regulation between TDP-43 and paraspeckles promotes pluripotency-differentiation transition M Modic, M Grosch, G Rot, S Schirge, T Lepko, T Yamazaki, FCY Lee, ... Molecular cell 74 (5), 951-965. e13, 2019 | 110 | 2019 |