Non-AUG translation: a new start for protein synthesis in eukaryotes MG Kearse, JE Wilusz Genes & development 31 (17), 1717-1731, 2017 | 376 | 2017 |
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response KM Green, MR Glineburg, MG Kearse, BN Flores, AE Linsalata, SJ Fedak, ... Nature communications 8 (1), 2005, 2017 | 232 | 2017 |
CGG repeat-associated non-AUG translation utilizes a cap-dependent scanning mechanism of initiation to produce toxic proteins MG Kearse, KM Green, A Krans, CM Rodriguez, AE Linsalata, ... Molecular cell 62 (2), 314-322, 2016 | 172 | 2016 |
NADPH oxidase-dependent and-independent mechanisms of reported inhibitors of reactive oxygen generation GJ Gatto Jr, Z Ao, MG Kearse, M Zhou, CR Morales, E Daniels, ... Journal of enzyme inhibition and medicinal chemistry 28 (1), 95-104, 2013 | 86 | 2013 |
Repeat‐associated non‐AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome A Krans, MG Kearse, PK Todd Annals of neurology 80 (6), 871-881, 2016 | 75 | 2016 |
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors MG Kearse, DH Goldman, J Choi, C Nwaezeapu, D Liang, KM Green, ... Genes & development 33 (13-14), 871-885, 2019 | 74 | 2019 |
A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis CM Rodriguez, SE Wright, MG Kearse, JM Haenfler, BN Flores, Y Liu, ... Nature Neuroscience 23 (3), 386-397, 2020 | 63 | 2020 |
Repeat-associated non-AUG translation and its impact in neurodegenerative disease MG Kearse, PK Todd Neurotherapeutics 11 (4), 721-731, 2014 | 51 | 2014 |
The nuclear export of circular RNAs is primarily defined by their length Z Li, MG Kearse, C Huang RNA biology 16 (1), 1-4, 2019 | 44 | 2019 |
Expression of ribosomal protein L22e family members in Drosophila melanogaster: rpL22-like is differentially expressed and alternatively spliced MG Kearse, AS Chen, VC Ware Nucleic acids research 39 (7), 2701-2716, 2011 | 43 | 2011 |
High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation KM Green, UJ Sheth, BN Flores, SE Wright, AB Sutter, MG Kearse, ... Journal of Biological Chemistry 294 (49), 18624-18638, 2019 | 42 | 2019 |
RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes MG Kearse, JA Ireland, SM Prem, AS Chen, VC Ware Nucleus 4 (3), 241-258, 2013 | 21 | 2013 |
Slowly emerging glycinergic transmission enhances inhibition in the sound localization pathway of the avian auditory system MJ Fischl, SR Weimann, MG Kearse, RM Burger Journal of neurophysiology 111 (3), 565-572, 2014 | 18 | 2014 |
Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster CM Mageeney, MG Kearse, BW Gershman, CE Pritchard, JM Colquhoun, ... Fly 12 (3-4), 143-163, 2018 | 15 | 2018 |
Translation reinitiation after uORFs does not fully protect mRNAs from nonsense-mediated decay PJ Russell, JA Slivka, EP Boyle, AHM Burghes, MG Kearse RNA 29 (6), 735-744, 2023 | 12 | 2023 |
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun 8: 2005 KM Green, MR Glineburg, MG Kearse, BN Flores, AE Linsalata, SJ Fedak, ... | 10 | 2017 |
A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes MKR Scarpitti, JE Warrick, EL Yoder, MG Kearse Journal of Biological Chemistry 298 (12), 2022 | 6 | 2022 |
Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits DJ Grove, DJ Levine, MG Kearse Nucleic Acids Research 51 (18), 9983-10000, 2023 | 5 | 2023 |
Small uORFs favor translation re-initiation but do not protect mRNAs from nonsense-mediated decay PJ Russell, JA Slivka, EP Boyle, AHM Burghes, MG Kearse bioRxiv, 2022.01. 10.475702, 2022 | 4 | 2022 |
A double on the Rocs with a twist: Rocaglamide A targets multiple DEAD-box helicases to inhibit translation initiation DJ DiVita, MG Kearse Cell Chemical Biology 28 (4), 431-433, 2021 | 3 | 2021 |