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Michael G. Kearse
Michael G. Kearse
在 osu.edu 的电子邮件经过验证 - 首页
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Non-AUG translation: a new start for protein synthesis in eukaryotes
MG Kearse, JE Wilusz
Genes & development 31 (17), 1717-1731, 2017
3762017
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response
KM Green, MR Glineburg, MG Kearse, BN Flores, AE Linsalata, SJ Fedak, ...
Nature communications 8 (1), 2005, 2017
2322017
CGG repeat-associated non-AUG translation utilizes a cap-dependent scanning mechanism of initiation to produce toxic proteins
MG Kearse, KM Green, A Krans, CM Rodriguez, AE Linsalata, ...
Molecular cell 62 (2), 314-322, 2016
1722016
NADPH oxidase-dependent and-independent mechanisms of reported inhibitors of reactive oxygen generation
GJ Gatto Jr, Z Ao, MG Kearse, M Zhou, CR Morales, E Daniels, ...
Journal of enzyme inhibition and medicinal chemistry 28 (1), 95-104, 2013
862013
Repeat‐associated non‐AUG translation from antisense CCG repeats in fragile X tremor/ataxia syndrome
A Krans, MG Kearse, PK Todd
Annals of neurology 80 (6), 871-881, 2016
752016
Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors
MG Kearse, DH Goldman, J Choi, C Nwaezeapu, D Liang, KM Green, ...
Genes & development 33 (13-14), 871-885, 2019
742019
A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis
CM Rodriguez, SE Wright, MG Kearse, JM Haenfler, BN Flores, Y Liu, ...
Nature Neuroscience 23 (3), 386-397, 2020
632020
Repeat-associated non-AUG translation and its impact in neurodegenerative disease
MG Kearse, PK Todd
Neurotherapeutics 11 (4), 721-731, 2014
512014
The nuclear export of circular RNAs is primarily defined by their length
Z Li, MG Kearse, C Huang
RNA biology 16 (1), 1-4, 2019
442019
Expression of ribosomal protein L22e family members in Drosophila melanogaster: rpL22-like is differentially expressed and alternatively spliced
MG Kearse, AS Chen, VC Ware
Nucleic acids research 39 (7), 2701-2716, 2011
432011
High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation
KM Green, UJ Sheth, BN Flores, SE Wright, AB Sutter, MG Kearse, ...
Journal of Biological Chemistry 294 (49), 18624-18638, 2019
422019
RpL22e, but not RpL22e-like-PA, is SUMOylated and localizes to the nucleoplasm of Drosophila meiotic spermatocytes
MG Kearse, JA Ireland, SM Prem, AS Chen, VC Ware
Nucleus 4 (3), 241-258, 2013
212013
Slowly emerging glycinergic transmission enhances inhibition in the sound localization pathway of the avian auditory system
MJ Fischl, SR Weimann, MG Kearse, RM Burger
Journal of neurophysiology 111 (3), 565-572, 2014
182014
Functional interplay between ribosomal protein paralogues in the eRpL22 family in Drosophila melanogaster
CM Mageeney, MG Kearse, BW Gershman, CE Pritchard, JM Colquhoun, ...
Fly 12 (3-4), 143-163, 2018
152018
Translation reinitiation after uORFs does not fully protect mRNAs from nonsense-mediated decay
PJ Russell, JA Slivka, EP Boyle, AHM Burghes, MG Kearse
RNA 29 (6), 735-744, 2023
122023
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun 8: 2005
KM Green, MR Glineburg, MG Kearse, BN Flores, AE Linsalata, SJ Fedak, ...
102017
A noncanonical RNA-binding domain of the fragile X protein, FMRP, elicits translational repression independent of mRNA G-quadruplexes
MKR Scarpitti, JE Warrick, EL Yoder, MG Kearse
Journal of Biological Chemistry 298 (12), 2022
62022
Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits
DJ Grove, DJ Levine, MG Kearse
Nucleic Acids Research 51 (18), 9983-10000, 2023
52023
Small uORFs favor translation re-initiation but do not protect mRNAs from nonsense-mediated decay
PJ Russell, JA Slivka, EP Boyle, AHM Burghes, MG Kearse
bioRxiv, 2022.01. 10.475702, 2022
42022
A double on the Rocs with a twist: Rocaglamide A targets multiple DEAD-box helicases to inhibit translation initiation
DJ DiVita, MG Kearse
Cell Chemical Biology 28 (4), 431-433, 2021
32021
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