The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases S Krasemann, C Madore, R Cialic, C Baufeld, N Calcagno, R El Fatimy, ... Immunity 47 (3), 566-581. e9, 2017 | 2052 | 2017 |
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development JFP Berbée, MR Boon, PPSJ Khedoe, A Bartelt, C Schlein, A Worthmann, ... Nature communications 6 (1), 6356, 2015 | 477 | 2015 |
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis A Worthmann, C John, MC Rühlemann, M Baguhl, FA Heinsen, ... Nature medicine 23 (7), 839-849, 2017 | 258 | 2017 |
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport A Bartelt, C John, N Schaltenberg, JFP Berbée, A Worthmann, ... Nature communications 8 (1), 15010, 2017 | 149 | 2017 |
Metabolic circuit involving free fatty acids, microRNA 122, and triglyceride synthesis in liver and muscle tissues C Chai, M Rivkin, L Berkovits, A Simerzin, E Zorde-Khvalevsky, ... Gastroenterology 153 (5), 1404-1415, 2017 | 97 | 2017 |
A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids C John, P Werner, A Worthmann, K Wegner, K Tödter, L Scheja, S Rohn, ... Journal of Chromatography A 1371, 184-195, 2014 | 73 | 2014 |
Lysosomal lipoprotein processing in endothelial cells stimulates adipose tissue thermogenic adaptation AW Fischer, MY Jaeckstein, K Gottschling, M Heine, F Sass, N Mangels, ... Cell metabolism 33 (3), 547-564. e7, 2021 | 47 | 2021 |
Endogenous fatty acid synthesis drives brown adipose tissue involution C Schlein, AW Fischer, F Sass, A Worthmann, K Tödter, MY Jaeckstein, ... Cell reports 34 (2), 2021 | 42 | 2021 |
Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1 S Dieckmann, A Strohmeyer, M Willershäuser, SF Maurer, W Wurst, ... American Journal of Physiology-Endocrinology and Metabolism, 2022 | 18 | 2022 |
Inulin supplementation disturbs hepatic cholesterol and bile acid metabolism independent from housing temperature MJ Pauly, JK Rohde, C John, I Evangelakos, AC Koop, P Pertzborn, ... Nutrients 12 (10), 3200, 2020 | 16 | 2020 |
A Gas Chromatography mass spectrometry-based method for the quantification of short chain fatty acids JK Rohde, MM Fuh, I Evangelakos, MJ Pauly, N Schaltenberg, F Siracusa, ... Metabolites 12 (2), 170, 2022 | 15 | 2022 |
Effects of pharmacological thermogenic adipocyte activation on metabolism and atherosclerotic plaque regression A Worthmann, C Schlein, JFP Berbée, PCN Rensen, J Heeren, A Bartelt Nutrients 11 (2), 463, 2019 | 14 | 2019 |
Short-term dietary changes can result in mucosal and systemic immune depression F Siracusa, N Schaltenberg, Y Kumar, TR Lesker, B Steglich, T Liwinski, ... Nature immunology 24 (9), 1473-1486, 2023 | 12 | 2023 |
Oxysterol 7-α hydroxylase (CYP7B1) attenuates metabolic-associated fatty liver disease in mice at thermoneutrality I Evangelakos, D Schwinge, A Worthmann, C John, N Roeder, ... Cells 10 (10), 2656, 2021 | 12 | 2021 |
TREM2 regulates the removal of apoptotic cells and inflammatory processes during the progression of NAFLD I Liebold, S Meyer, M Heine, A Kuhl, J Witt, L Eissing, AW Fischer, ... Cells 12 (3), 341, 2023 | 10 | 2023 |
Endothelial lipase is involved in cold-induced high-density lipoprotein turnover and reverse cholesterol transport in mice N Schaltenberg, C John, M Heine, F Haumann, F Rinninger, L Scheja, ... Frontiers in Cardiovascular Medicine 8, 628235, 2021 | 10 | 2021 |
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use A Worthmann, J Ridder, SYL Piel, I Evangelakos, M Musfeldt, H Voß, ... Nature Communications 15 (1), 45, 2024 | 4 | 2024 |
TREM2-Positive lipid-associated macrophages (LAMs) control white adipose tissue remodeling and metabolic adaptation in obesity A Worthmann, J Heeren Immunometabolism 2 (2), e200014, 2020 | 3 | 2020 |
Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages I Liebold, A Al Jawazneh, C Casar, C Lanzloth, S Leyk, M Hamley, ... Science 384 (6691), eabo7027, 2024 | 2 | 2024 |
A liquid chromatography-tandem mass spectrometry based method for the quantification of adenosine nucleotides and NAD precursors and products in various biological samples J Hiefner, J Rische, MJ Bunders, A Worthmann Frontiers in immunology 14, 1250762, 2023 | 2 | 2023 |