Absorption and drug development: solubility, permeability, and charge state A Avdeef John Wiley & Sons, 2012 | 1099 | 2012 |
Physicochemical profiling (solubility, permeability and charge state) A Avdeef Current topics in medicinal chemistry 1 (4), 277-351, 2001 | 729 | 2001 |
Coexistence of passive and carrier-mediated processes in drug transport K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ... Nature reviews Drug discovery 9 (8), 597-614, 2010 | 669 | 2010 |
pH-Metric logP 10. Determination of liposomal membrane-water partition coefficients of lonizable drugs A Avdeef, KJ Box, JEA Comer, C Hibbert, KY Tam Pharmaceutical research 15, 209-215, 1998 | 530 | 1998 |
Coordination chemistry of microbial iron transport compounds. 9. Stability constants for catechol models of enterobactin A Avdeef, SR Sofen, TL Bregante, KN Raymond Journal of the American Chemical Society 100 (17), 5362-5370, 1978 | 444 | 1978 |
Coordination chemistry of microbial iron transport compounds. 19. Stability constants and electrochemical behavior of ferric enterobactin and model complexes WR Harris, CJ Carrano, SR Cooper, SR Sofen, AE Avdeef, JV McArdle, ... Journal of the American Chemical Society 101 (20), 6097-6104, 1979 | 401 | 1979 |
pH-metric solubility. 2: correlation between the acid-base titration and the saturation shake-flask solubility-pH methods A Avdeef, CM Berger, C Brownell Pharmaceutical research 17, 85-89, 2000 | 344 | 2000 |
Absorption classification of oral drugs based on molecular surface properties CAS Bergström, M Strafford, L Lazorova, A Avdeef, K Luthman, ... Journal of medicinal chemistry 46 (4), 558-570, 2003 | 338 | 2003 |
Solubility of sparingly-soluble ionizable drugs A Avdeef Advanced drug delivery reviews 59 (7), 568-590, 2007 | 335 | 2007 |
PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures A Avdeef, KJ Box, JEA Comer, M Gilges, M Hadley, C Hibbert, ... Journal of pharmaceutical and biomedical analysis 20 (4), 631-641, 1999 | 307 | 1999 |
pH-Metric log P. 3. Glass electrode calibration in methanol-water, applied to pKa determination of water-insoluble substances A Avdeef, JEA Comer, SJ Thomson Analytical Chemistry 65 (1), 42-49, 1993 | 297 | 1993 |
Classification analysis of P-glycoprotein substrate specificity R Didziapetris, P Japertas, A Avdeef, A Petrauskas Journal of drug targeting 11 (7), 391-406, 2003 | 285 | 2003 |
pH-metric log P. II: Refinement of partition coefficients and ionization constants of multiprotic substances A Avdeef Journal of pharmaceutical sciences 82 (2), 183-190, 1993 | 285 | 1993 |
PAMPA—critical factors for better predictions of absorption A Avdeef, S Bendels, L Di, B Faller, M Kansy, K Sugano, Y Yamauchi Journal of pharmaceutical sciences 96 (11), 2893-2909, 2007 | 259 | 2007 |
The rise of PAMPA A Avdeef Expert opinion on drug metabolism & toxicology 1 (2), 325-342, 2005 | 243 | 2005 |
PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones M Bermejo, A Avdeef, A Ruiz, R Nalda, JA Ruell, O Tsinman, I González, ... European Journal of Pharmaceutical Sciences 21 (4), 429-441, 2004 | 233 | 2004 |
Caco-2 permeability of weakly basic drugs predicted with the Double-Sink PAMPA pKaflux method A Avdeef, P Artursson, S Neuhoff, L Lazorova, J Gråsjö, S Tavelin European journal of pharmaceutical sciences 24 (4), 333-349, 2005 | 230 | 2005 |
PH‐metric log P. Part 1. Difference plots for determining ion‐pair octanol‐water partition coefficients of multiprotic substances A Avdeef Quantitative Structure‐Activity Relationships 11 (4), 510-517, 1992 | 221 | 1992 |
In vitro trans-monolayer permeability calculations: often forgotten assumptions KA Youdim, A Avdeef, NJ Abbott Drug discovery today 8 (21), 997-1003, 2003 | 208 | 2003 |
Skin–PAMPA: A new method for fast prediction of skin penetration B Sinkó, TM Garrigues, GT Balogh, ZK Nagy, O Tsinman, A Avdeef, ... European Journal of Pharmaceutical Sciences 45 (5), 698-707, 2012 | 203 | 2012 |