SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation JA Steens, Y Zhu, DW Taylor, JPK Bravo, SHP Prinsen, CD Schoen, ... Nature communications 12 (1), 5033, 2021 | 69 | 2021 |
Coevolution between bacterial CRISPR-Cas systems and their bacteriophages BNJ Watson, JA Steens, RHJ Staals, ER Westra, S van Houte Cell host & microbe 29 (5), 715-725, 2021 | 67 | 2021 |
Structure of a type IV CRISPR-Cas ribonucleoprotein complex Y Zhou, JPK Bravo, HN Taylor, JA Steens, RN Jackson, RHJ Staals, ... Iscience 24 (3), 2021 | 29 | 2021 |
The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors JA Steens, CRP Salazar, RHJ Staals Biochemical Society Transactions 50 (5), 1353-1364, 2022 | 26 | 2022 |
Type III-B CRISPR-Cas cascade of proteolytic cleavages JA Steens, JPK Bravo, CRP Salazar, C Yildiz, AM Amieiro, S Köstlbacher, ... Science 383 (6682), 512-519, 2024 | 14 | 2024 |
Structure of a type IV CRISPR-Cas ribonucleoprotein complex. iScience 24 Y Zhou, JPK Bravo, HN Taylor, JA Steens, RN Jackson, RHJ Staals, ... | 13 | 2021 |
SCOPE: flexible targeting and stringent CARF activation enables type III CRISPR-Cas diagnostics JA Steens, Y Zhu, DW Taylor, JPK Bravo, SHP Prinsen, CD Schoen, ... BioRxiv, 2021.02. 01.429135, 2021 | 7 | 2021 |
SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. Nat Commun 12: 1–12 JA Steens, Y Zhu, DW Taylor, JPK Bravo, SHP Prinsen, CD Schoen, ... | 5 | 2021 |
Structure of a type IV CRISPR-Cas effector complex Y Zhou, JPK Bravo, HN Taylor, J Steens, RN Jackson, RHJ Staals, ... bioRxiv, 2020.07. 31.231399, 2020 | 5 | 2020 |
Nanopores Reveal the Stoichiometry of Single Oligoadenylates Produced by Type III CRISPR-Cas DF Navas, JA Steens, C de Lannoy, B Noordijk, M Pfeffer, D de Ridder, ... ACS nano 18 (26), 16505, 2024 | 2 | 2024 |
Nanopores Reveal the Stoichiometry of Single Oligoadenylates Produced by Type III CRISPR-Cas D Fuentenebro Navas, JA Steens, C de Lannoy, B Noordijk, M Pfeffer, ... ACS Nano 18 (26), 16505-16515, 2024 | 2 | 2024 |
Compact but mighty: Biology and applications of type III-E CRISPR-Cas systems JA Steens, J van der Oost, RHJ Staals Molecular Cell 82 (23), 4405-4406, 2022 | 2 | 2022 |
Foute cellen zichzelf laten opofferen R Staals, J Steens | | 2024 |
The exploration & exploitation of CRISPR-Cas type III defence strategies AJ Steens PQDT-Global, 2024 | | 2024 |
Thermostable RNA polymerase AJ Steens, RHJ Staals, J Van Der Oost WO Patent 2,023,140,731, 2023 | | 2023 |
Type III CRISPR/Cas-based Diagnostics AJ Steens, SHP Prinsen, J Van Der Oost, RHJ Staals US Patent App. 17/619,773, 2022 | | 2022 |
The applicability of in house designed easy-operable LAMP and LAMP/CRISPR-Cas assays for a variety of targets in real-life food samples. MM Voorhuijzen, PJM Bonants, V Kurm, A van Amerongen, GA de Groot, ... 14th Conference RME 2022: Rapid Analysis and Diagnostics 2022, 2022 | | 2022 |
Type III CRISPR-Cas-from Structure-function Analyses to Diagnostics JA STEENS, ZHU Yifan, J VAN DER OOST, RHJ STAALS 한국생물공학회 학술대회, 5-5, 2021 | | 2021 |
Type III CRISPR/CAS-based diagnostics AJ Steens, SHP Prinsen, J Van Der Oost, RHJ Staals WO Patent 2,020,256,553, 2020 | | 2020 |