| Generation of hydrogen peroxide primarily contributes to the induction of Fe (II)-dependent apoptosis in Jurkat cells by (−)-epigallocatechin gallate H Nakagawa, K Hasumi, JT Woo, K Nagai, M Wachi Carcinogenesis 25 (9), 1567-1574, 2004 | 291 | 2004 |
| Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber A Endo, K Hasumi, S Negishi The Journal of Antibiotics 38 (3), 420-422, 1985 | 202 | 1985 |
| Dihydromonacolin L and monacolin X, new metabolites those inhibit cholesterol biosynthesis A Endo, K Hasumi, T NAKAMURA, M KUNISHIMA, M MASUDA The Journal of Antibiotics 38 (3), 321-327, 1985 | 145 | 1985 |
| Effects of mulberry leaf extract rich in 1-deoxynojirimycin on blood lipid profiles in humans Y Kojima, T Kimura, K Nakagawa, A Asai, K Hasumi, S Oikawa, ... Journal of Clinical Biochemistry and Nutrition 47 (2), 155-161, 2010 | 137 | 2010 |
| Isolation, characterization and biological activities of concanamycins as inhibitors of lysosomal acidification JT Woo, C SHINOHARA, K SAKAI, K HASUMI, A ENDO The Journal of Antibiotics 45 (7), 1108-1116, 1992 | 110 | 1992 |
| HMG-CoA reductase inhibitors A Endo, K Hasumi Natural Product Reports 10 (6), 541-550, 1993 | 102 | 1993 |
| Enhancement of plasminogen activation by surfactin C: augmentation of fibrinolysis in vitro and in vivo T Kikuchi, K Hasumi Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2002 | 99 | 2002 |
| Competitive inhibition of squalene synthetase by squalestatin 1 K HASUMI, K TACHIKAWA, K SAKAI, S MURAKAWA, N YOSHIKAWA, ... The Journal of antibiotics 46 (4), 689-691, 1993 | 96 | 1993 |
| The synthesis of compactin (ML-236B) and monacolin K in fungi A ENDO, K HASUMI, A YAMADA, R SHIMODA, H TAKESHIMA The Journal of antibiotics 39 (11), 1609-1610, 1986 | 85 | 1986 |
| Extracellular histone induces plasma hyaluronan-binding protein (factor VII activating protease) activation in vivo S Yamamichi, Y Fujiwara, T Kikuchi, M Nishitani, Y Matsushita, K Hasumi Biochemical and biophysical research communications 409 (3), 483-488, 2011 | 76 | 2011 |
| Human immunodeficiency virus type 1 Nef-induced CD4 cell surface downregulation is inhibited by ikarugamycin T Luo, BL Fredericksen, K Hasumi, A Endo, JV Garcia Journal of virology 75 (5), 2488-2492, 2001 | 75 | 2001 |
| Isolation, characterization and biological activities of novel triprenyl phenols as pancreatic cholesterol esterase inhibitors produced by Stachybotrys sp. F-1839 K Sakai, K Watanabe, K Masuda, M Tsuji, K Hasumi, A Endo The Journal of Antibiotics 48 (6), 447-456, 1995 | 70 | 1995 |
| Inhibition of the acidification of endosomes and lysosomes by the antibiotic concanamycin B in macrophage J774 JT WOO, C Shinohara, K SAKAI, K HASUMI, A ENDO European journal of biochemistry 207 (1), 383-389, 1992 | 69 | 1992 |
| Small‐molecule modulators of zymogen activation in the fibrinolytic and coagulation systems K Hasumi, S Yamamichi, T Harada The FEBS journal 277 (18), 3675-3687, 2010 | 68 | 2010 |
| Glucose-dependent active ATP depletion by koningic acid kills high-glycolytic cells S Kumagai, R Narasaki, K Hasumi Biochemical and biophysical research communications 365 (2), 362-368, 2008 | 68 | 2008 |
| Activation of fibrinolysis by SMTP-7 and-8, novel staplabin analogs with a pseudosymmetric structure W Hu, S Ohyama, K Hasumi The Journal of Antibiotics 53 (3), 241-247, 2000 | 67 | 2000 |
| Inhibition of the uptake of oxidized low‐density lipoprotein in macrophage J774 by the antibiotic ikarugamycin K Hasumi, C Shinohara, S Naganuma, A Endo European journal of biochemistry 205 (2), 841-846, 1992 | 66 | 1992 |
| Distinct effects of tissue-type plasminogen activator and SMTP-7 on cerebrovascular inflammation following thrombolytic reperfusion T Miyazaki, Y Kimura, H Ohata, T Hashimoto, K Shibata, K Hasumi, ... Stroke 42 (4), 1097-1104, 2011 | 65 | 2011 |
| Staplabin, a novel fungal triprenyl phenol which stimulates the binding of plasminogen to fibrin and U937 cells C Shinohara, K Hasumi, W Hatsumi, A Endo The Journal of Antibiotics 49 (10), 961-966, 1996 | 65 | 1996 |
| A novel finding of a low-molecular-weight compound, SMTP-7, having thrombolytic and anti-inflammatory effects in cerebral infarction of mice K Shibata, T Hashimoto, K Nobe, K Hasumi, K Honda Naunyn-Schmiedeberg's archives of pharmacology 382, 245-253, 2010 | 58 | 2010 |
