| The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent RM Mancina, P Dongiovanni, S Petta, P Pingitore, M Meroni, R Rametta, ... Gastroenterology 150 (5), 1219-1230. e6, 2016 | 652 | 2016 |
| PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells C Pirazzi, L Valenti, BM Motta, P Pingitore, K Hedfalk, RM Mancina, ... Human molecular genetics 23 (15), 4077-4085, 2014 | 389 | 2014 |
| Causal relationship of hepatic fat with liver damage and insulin resistance in nonalcoholic fatty liver P Dongiovanni, S Stender, A Pietrelli, RM Mancina, A Cespiati, S Petta, ... Journal of internal medicine 283 (4), 356-370, 2018 | 319 | 2018 |
| Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function P Pingitore, C Pirazzi, RM Mancina, BM Motta, C Indiveri, A Pujia, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 231 | 2014 |
| Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice D Lindén, A Ahnmark, P Pingitore, E Ciociola, I Ahlstedt, AC Andréasson, ... Molecular metabolism 22, 49-61, 2019 | 191 | 2019 |
| PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis P Pingitore, P Dongiovanni, BM Motta, M Meroni, SM Lepore, ... Human molecular genetics 25 (23), 5212-5222, 2016 | 132 | 2016 |
| The rs2294918 E434K variant modulates patatin‐like phospholipase domain‐containing 3 expression and liver damage B Donati, BM Motta, P Pingitore, M Meroni, A Pietrelli, A Alisi, S Petta, ... Hepatology 63 (3), 787-798, 2016 | 131 | 2016 |
| Human multilineage 3D spheroids as a model of liver steatosis and fibrosis P Pingitore, K Sasidharan, M Ekstrand, S Prill, D Lindén, S Romeo International journal of molecular sciences 20 (7), 1629, 2019 | 118 | 2019 |
| The role of PNPLA3 in health and disease P Pingitore, S Romeo Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019 | 108 | 2019 |
| The TM6SF2 E167K genetic variant induces lipid biosynthesis and reduces apolipoprotein B secretion in human hepatic 3D spheroids S Prill, A Caddeo, G Baselli, O Jamialahmadi, P Dongiovanni, R Rametta, ... Scientific reports 9 (1), 11585, 2019 | 101 | 2019 |
| Liver transcriptomics highlights interleukin-32 as novel NAFLD-related cytokine and candidate biomarker GA Baselli, P Dongiovanni, R Rametta, M Meroni, S Pelusi, M Maggioni, ... Gut 69 (10), 1855-1866, 2020 | 87 | 2020 |
| Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris—Functional and kinetic asymmetry revealed in proteoliposomes P Pingitore, L Pochini, M Scalise, M Galluccio, K Hedfalk, C Indiveri Biochimica Et Biophysica Acta (BBA)-Biomembranes 1828 (9), 2238-2246, 2013 | 78 | 2013 |
| Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5) M Scalise, L Pochini, S Panni, P Pingitore, K Hedfalk, C Indiveri Amino Acids 46, 2463-2475, 2014 | 77 | 2014 |
| MBOAT7 is anchored to endomembranes by six transmembrane domains A Caddeo, O Jamialahmadi, G Solinas, A Pujia, RM Mancina, P Pingitore, ... Journal of Structural Biology 206 (3), 349-360, 2019 | 58 | 2019 |
| Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease B Donati, A Pietrelli, P Pingitore, P Dongiovanni, A Caddeo, L Walker, ... Cancer medicine 6 (8), 1930-1940, 2017 | 53 | 2017 |
| Cysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporter M Scalise, L Pochini, P Pingitore, K Hedfalk, C Indiveri FEBS letters 589 (23), 3617-3623, 2015 | 52 | 2015 |
| Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia P Pingitore, SM Lepore, C Pirazzi, RM Mancina, BM Motta, L Valenti, ... Journal of clinical lipidology 10 (4), 816-823, 2016 | 39 | 2016 |
| PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes RM Mancina, R Spagnuolo, M Milano, S Brogneri, A Morrone, C Cosco, ... Inflammatory Bowel Diseases 22 (1), 134-140, 2016 | 39 | 2016 |
| DEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection MA Burza, BM Motta, RM Mancina, P Pingitore, C Pirazzi, SM Lepore, ... Hepatology 63 (2), 418-427, 2016 | 37 | 2016 |
| Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings BE Schwartz, V Rajagopal, C Smith, E Cohick, G Whissell, M Gamboa, ... Cells 9 (10), 2247, 2020 | 34 | 2020 |
