Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction RL Kember, R Vickers-Smith, H Xu, S Toikumo, M Niarchou, H Zhou, ... Nature Neuroscience 25 (10), 1279-1287, 2022 | 53 | 2022 |
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals H Zhou, RL Kember, JD Deak, H Xu, S Toikumo, K Yuan, PA Lind, ... Nature Medicine 29 (12), 3184-3192, 2023 | 47 | 2023 |
Childhood trauma, the stress response and metabolic syndrome: a focus on DNA methylation SMJ Womersley, J. S., Nothling, J., Toikumo, S., Malan-Müller, S., van den ... European Journal of Neuroscience, 2021 | 33* | 2021 |
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits S Toikumo, H Xu, J Gelernter, RL Kember, HR Kranzler Neuropsychopharmacology, 1-8, 2022 | 18 | 2022 |
Genome-wide differentially methylated genes associated with posttraumatic stress disorder and longitudinal change in methylation in rape survivors J Nöthling, N Abrahams, S Toikumo, M Suderman, S Mhlongo, ... Translational Psychiatry 11 (1), 594, 2021 | 13 | 2021 |
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain RL Kember, R Vickers-Smith, H Xu, S Toikumo, M Niarchou, H Zhou, ... medRxiv, 2021.12. 13.21267480, 2021 | 9 | 2021 |
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes S Toikumo, MV Jennings, BK Pham, H Lee, TT Mallard, SB Bianchi, ... Nature Human Behaviour, 1-17, 2024 | 8 | 2024 |
A multi-ancestry genetic study of pain intensity in 598,339 veterans S Toikumo, R Vickers-Smith, Z Jinwala, H Xu, D Saini, EE Hartwell, ... Nature medicine 30 (4), 1075-1084, 2024 | 8 | 2024 |
Identifying genetic loci and phenomic associations of substance use traits: A multi‐trait analysis of GWAS (MTAG) study H Xu, S Toikumo, RC Crist, K Glogowska, Z Jinwala, JD Deak, AC Justice, ... Addiction 118 (10), 1942-1952, 2023 | 8 | 2023 |
The relationship between alcohol-and sleep-related traits: results from polygenic risk score and Mendelian randomization analyses S Chakravorty, RL Kember, DR Mazzotti, HS Dashti, S Toikumo, ... Drug and Alcohol Dependence 251, 110912, 2023 | 6 | 2023 |
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes S Toikumo, MV Jennings, BK Pham, H Lee, TT Mallard, SB Bianchi, ... medRxiv, 2023 | 5 | 2023 |
Does polygenic risk for substance‐related traits predict ages of onset and progression of symptoms? HR Kranzler, R Feinn, H Xu, BL Ho, D Saini, OR Nicastro, A Jacoby, ... Addiction 118 (9), 1675-1686, 2023 | 5 | 2023 |
The genetic architecture of pain intensity in a sample of 598,339 US veterans S Toikumo, R Vickers-Smith, Z Jinwala, H Xu, D Saini, E Hartwell, ... medRxiv, 2023 | 5 | 2023 |
Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample Y Khan, CN Davis, Z Jinwala, KL Feuer, S Toikumo, EE Hartwell, ... medRxiv, 2024 | 2 | 2024 |
Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program Y Cheng, C Dao, H Zhou, B Li, RL Kember, S Toikumo, H Zhao, ... Translational Psychiatry 13 (1), 148, 2023 | 2 | 2023 |
Multi-trait Analysis of GWAS (MTAG) of Substance Use Traits Identifies Novel Genetic Loci and Phenomic Associations H Xu, S Toikumo, RC Crist, K Glogowska, JD Deak, J Gelernter, ... medRxiv, 2022 | 1 | 2022 |
Epigenome-Wide Association Study on Posttraumatic Stress Disorder Diagnosis and Metabolic Syndrome in a South African Population S Toikumo, S Malan-Muller, P Swart, J Womersley, L van den Heuvel, ... European Neuropsychopharmacology, 2019 | 1 | 2019 |
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens BC Reiner, SN Chehimi, R Merkel, S Toikumo, WH Berrettini, HR Kranzler, ... Scientific Reports 14 (1), 18258, 2024 | | 2024 |
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans CN Davis, Z Jinwala, AS Hatoum, S Toikumo, A Agrawal, CT Rentsch, ... medRxiv, 2024 | | 2024 |
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra CN Davis, Y Khan, S Toikumo, Z Jinwala, DI Boomsma, DF Levey, ... medRxiv, 2024 | | 2024 |