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Sylvanus Toikumo
Sylvanus Toikumo
Postdoctoral Researcher, University of Pennsylvania
在 pennmedicine.upenn.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction
RL Kember, R Vickers-Smith, H Xu, S Toikumo, M Niarchou, H Zhou, ...
Nature Neuroscience 25 (10), 1279-1287, 2022
532022
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
H Zhou, RL Kember, JD Deak, H Xu, S Toikumo, K Yuan, PA Lind, ...
Nature Medicine 29 (12), 3184-3192, 2023
472023
Childhood trauma, the stress response and metabolic syndrome: a focus on DNA methylation
SMJ Womersley, J. S., Nothling, J., Toikumo, S., Malan-Müller, S., van den ...
European Journal of Neuroscience, 2021
33*2021
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits
S Toikumo, H Xu, J Gelernter, RL Kember, HR Kranzler
Neuropsychopharmacology, 1-8, 2022
182022
Genome-wide differentially methylated genes associated with posttraumatic stress disorder and longitudinal change in methylation in rape survivors
J Nöthling, N Abrahams, S Toikumo, M Suderman, S Mhlongo, ...
Translational Psychiatry 11 (1), 594, 2021
132021
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain
RL Kember, R Vickers-Smith, H Xu, S Toikumo, M Niarchou, H Zhou, ...
medRxiv, 2021.12. 13.21267480, 2021
92021
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes
S Toikumo, MV Jennings, BK Pham, H Lee, TT Mallard, SB Bianchi, ...
Nature Human Behaviour, 1-17, 2024
82024
A multi-ancestry genetic study of pain intensity in 598,339 veterans
S Toikumo, R Vickers-Smith, Z Jinwala, H Xu, D Saini, EE Hartwell, ...
Nature medicine 30 (4), 1075-1084, 2024
82024
Identifying genetic loci and phenomic associations of substance use traits: A multi‐trait analysis of GWAS (MTAG) study
H Xu, S Toikumo, RC Crist, K Glogowska, Z Jinwala, JD Deak, AC Justice, ...
Addiction 118 (10), 1942-1952, 2023
82023
The relationship between alcohol-and sleep-related traits: results from polygenic risk score and Mendelian randomization analyses
S Chakravorty, RL Kember, DR Mazzotti, HS Dashti, S Toikumo, ...
Drug and Alcohol Dependence 251, 110912, 2023
62023
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes
S Toikumo, MV Jennings, BK Pham, H Lee, TT Mallard, SB Bianchi, ...
medRxiv, 2023
52023
Does polygenic risk for substance‐related traits predict ages of onset and progression of symptoms?
HR Kranzler, R Feinn, H Xu, BL Ho, D Saini, OR Nicastro, A Jacoby, ...
Addiction 118 (9), 1675-1686, 2023
52023
The genetic architecture of pain intensity in a sample of 598,339 US veterans
S Toikumo, R Vickers-Smith, Z Jinwala, H Xu, D Saini, E Hartwell, ...
medRxiv, 2023
52023
Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample
Y Khan, CN Davis, Z Jinwala, KL Feuer, S Toikumo, EE Hartwell, ...
medRxiv, 2024
22024
Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
Y Cheng, C Dao, H Zhou, B Li, RL Kember, S Toikumo, H Zhao, ...
Translational Psychiatry 13 (1), 148, 2023
22023
Multi-trait Analysis of GWAS (MTAG) of Substance Use Traits Identifies Novel Genetic Loci and Phenomic Associations
H Xu, S Toikumo, RC Crist, K Glogowska, JD Deak, J Gelernter, ...
medRxiv, 2022
12022
Epigenome-Wide Association Study on Posttraumatic Stress Disorder Diagnosis and Metabolic Syndrome in a South African Population
S Toikumo, S Malan-Muller, P Swart, J Womersley, L van den Heuvel, ...
European Neuropsychopharmacology, 2019
12019
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens
BC Reiner, SN Chehimi, R Merkel, S Toikumo, WH Berrettini, HR Kranzler, ...
Scientific Reports 14 (1), 18258, 2024
2024
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans
CN Davis, Z Jinwala, AS Hatoum, S Toikumo, A Agrawal, CT Rentsch, ...
medRxiv, 2024
2024
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra
CN Davis, Y Khan, S Toikumo, Z Jinwala, DI Boomsma, DF Levey, ...
medRxiv, 2024
2024
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