The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs ST LoPresti, ML Arral, N Chaudhary, KA Whitehead Journal of Controlled Release 345, 819-831, 2022 | 120 | 2022 |
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer JR Melamed, SS Yerneni, ML Arral, ST LoPresti, N Chaudhary, ... Science Advances 9 (4), eade1444, 2023 | 61 | 2023 |
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery JR Melamed, KA Hajj, N Chaudhary, D Strelkova, ML Arral, N Pardi, ... Journal of Controlled Release 341, 206-214, 2022 | 47 | 2022 |
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism DMS Petersen, N Chaudhary, ML Arral, RM Weiss, KA Whitehead European Journal of Pharmaceutics and Biopharmaceutics 192, 126-135, 2023 | 13 | 2023 |
Electrochemical detection of NG-hydroxy-L-arginine ML Arral, JM Halpern ECS transactions 85 (13), 1163, 2018 | 8 | 2018 |
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... Proceedings of the National Academy of Sciences 121 (11), e2307810121, 2024 | 7 | 2024 |
Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation KC Fein, ML Arral, JS Kim, AN Newby, KA Whitehead Journal of Controlled Release 361, 29-39, 2023 | 5 | 2023 |
Lipid nanoparticle structure and delivery route during pregnancy dictates mRNA potency, immunogenicity, and health in the mother and offspring N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... bioRxiv, 2023.02. 15.528720, 2023 | 5 | 2023 |
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer. Sci Adv 9 (4): eade1444 JR Melamed, SS Yerneni, ML Arral, ST LoPresti, N Chaudhary, ... | 5 | 2023 |
Elucidating the electrochemical mechanism of NG-hydroxy-L-arginine ML Arral, C Tooley, E Ziino, JM Halpern Journal of the Electrochemical Society 167 (2), 025501, 2020 | 4 | 2020 |
Work-in-Progress: Inclusive Mentoring Strategies for Neurodivergent Undergraduate Researchers in STEM J Halpern, M Arral, J Gesun 2022 ASEE Annual Conference & Exposition, 2022 | 2 | 2022 |
Synthetic strategy for mRNA encapsulation and gene delivery with metal-organic frameworks H Lawson, H Nguyen, A Tupe, M Arral, K Lee, M Lu, K Whitehead, ... | 1 | 2024 |
10 Tips to Make Your Course More Accessible and Inclusive to Disabled Students M Arral 2022 ASEE Annual Conference & Exposition, 2022 | 1 | 2022 |
Nanoparticles for RNA Therapeutics: Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... Proceedings of the National Academy of Sciences of the United States of …, 2024 | | 2024 |
Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape without Side Effects S Omo-Lamai, Y Wang, MN Patel, E Essien, M Shen, A Majumder, C Espy, ... bioRxiv, 2024.04. 16.589801, 2024 | | 2024 |
Branched‐Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice DMS Petersen, RM Weiss, KA Hajj, SS Yerneni, N Chaudhary, AN Newby, ... Advanced Healthcare Materials, 2400225, 0 | | |