| Accelerated ageing of the lung in COPD: new concepts N Mercado, K Ito, PJ Barnes Thorax 70 (5), 482-489, 2015 | 424 | 2015 |
| Decreased histone deacetylase 2 impairs Nrf2 activation by oxidative stress N Mercado, R Thimmulappa, CMR Thomas, PS Fenwick, KK Chana, ... Biochemical and biophysical research communications 406 (2), 292-298, 2011 | 237 | 2011 |
| Denitrosylation of HDAC2 by targeting Nrf2 restores glucocorticosteroid sensitivity in macrophages from COPD patients D Malhotra, RK Thimmulappa, N Mercado, K Ito, P Kombairaju, S Kumar, ... The Journal of clinical investigation 121 (11), 4289-4302, 2011 | 166 | 2011 |
| Dysfunction of endothelial progenitor cells from smokers and chronic obstructive pulmonary disease patients due to increased DNA damage and senescence KE Paschalaki, RD Starke, Y Hu, N Mercado, A Margariti, VG Gorgoulis, ... Stem cells 31 (12), 2813-2826, 2013 | 154 | 2013 |
| Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma N Mercado, A Hakim, Y Kobayashi, S Meah, OS Usmani, KF Chung, ... PloS one 7 (7), e41582, 2012 | 137 | 2012 |
| Nortriptyline reverses corticosteroid insensitivity by inhibition of phosphoinositide-3-kinase-δ N Mercado, Y To, K Ito, PJ Barnes Journal of Pharmacology and Experimental Therapeutics 337 (2), 465-470, 2011 | 115 | 2011 |
| Passive smoking impairs histone deacetylase-2 in children with severe asthma Y Kobayashi, C Bossley, A Gupta, K Akashi, L Tsartsali, N Mercado, ... Chest 145 (2), 305-312, 2014 | 111 | 2014 |
| Defects of protein phosphatase 2A causes corticosteroid insensitivity in severe asthma Y Kobayashi, N Mercado, PJ Barnes, K Ito PloS one 6 (12), e27627, 2011 | 111 | 2011 |
| Restoration of corticosteroid sensitivity in chronic obstructive pulmonary disease by inhibition of mammalian target of rapamycin A Mitani, K Ito, C Vuppusetty, PJ Barnes, N Mercado American journal of respiratory and critical care medicine 193 (2), 143-153, 2016 | 93 | 2016 |
| Geroprotectors as a novel therapeutic strategy for COPD, an accelerating aging disease K Ito, T Colley, N Mercado International Journal of Chronic Obstructive Pulmonary Disease, 641-652, 2012 | 86 | 2012 |
| Bromodomain and extraterminal proteins suppress NF-E2–related factor 2–mediated antioxidant gene expression C Michaeloudes, N Mercado, C Clarke, PK Bhavsar, IM Adcock, ... The Journal of Immunology 192 (10), 4913-4920, 2014 | 71 | 2014 |
| Increased corticosteroid sensitivity by a long acting β2 agonist formoterol via β2 adrenoceptor independent protein phosphatase 2A activation Y Kobayashi, N Mercado, A Miller-Larsson, PJ Barnes, K Ito Pulmonary pharmacology & therapeutics 25 (3), 201-207, 2012 | 52 | 2012 |
| STOP accelerating lung aging for the treatment of COPD K Ito, N Mercado Experimental Gerontology 59, 21-27, 2014 | 48 | 2014 |
| Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma T Colley, N Mercado, Y Kunori, C Brightling, PK Bhavsar, PJ Barnes, K Ito Journal of Allergy and Clinical Immunology 137 (5), 1595-1597. e7, 2016 | 42 | 2016 |
| Quercetin restores corticosteroid sensitivity in cells from patients with chronic obstructive pulmonary disease A Mitani, A Azam, C Vuppusetty, K Ito, N Mercado, PJ Barnes Experimental Lung Research 43 (9-10), 417-425, 2017 | 39 | 2017 |
| Activation of transcription factor Nrf2 signalling by the sphingosine kinase inhibitor SKI-II is mediated by the formation of Keap1 dimers N Mercado, Y Kizawa, K Ueda, Y Xiong, G Kimura, A Moses, JM Curtis, ... PLoS One 9 (2), e88168, 2014 | 39 | 2014 |
| IRF2 is a master regulator of human keratinocyte stem cell fate N Mercado, G Schutzius, C Kolter, D Estoppey, S Bergling, G Roma, ... Nature communications 10 (1), 4676, 2019 | 29 | 2019 |
| Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation Y Kono, T Colley, M To, AI Papaioannou, N Mercado, JR Baker, Y To, ... Scientific Reports 11 (1), 335, 2021 | 28 | 2021 |
| Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer S Alzoubi, L Brody, S Rahman, AL Mahul-Mellier, N Mercado, K Ito, ... Oncotarget 7 (28), 44505, 2016 | 26 | 2016 |
| Dysfunction of endothelial progenitor cells from smokers and COPD patients due to increased DNA damage and senescence KE Paschalaki, RD Starke, Y Hu, N Mercado, A Margariti, VG Gorgoulis, ... Stem Cells 31 (12), 2813-26, 2013 | 23 | 2013 |
Peter J BarnesImperial College London在 imperial.ac.uk 的电子邮件经过验证
