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Egor A. Syroegin
标题
引用次数
引用次数
年份
A synthetic antibiotic class overcoming bacterial multidrug resistance
MJ Mitcheltree, A Pisipati, EA Syroegin, KJ Silvestre, D Klepacki, ...
Nature 599 (7885), 507-512, 2021
1572021
Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance
MS Svetlov, EA Syroegin, EV Aleksandrova, GC Atkinson, ST Gregory, ...
Nature chemical biology 17 (4), 412-420, 2021
922021
Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol
EA Syroegin, L Flemmich, D Klepacki, N Vazquez-Laslop, R Micura, ...
Nature structural & molecular biology 29 (2), 152-161, 2022
502022
Insights into the ribosome function from the structures of non-arrested ribosome–nascent chain complexes
EA Syroegin, EV Aleksandrova, YS Polikanov
Nature chemistry 15 (1), 143-153, 2023
362023
Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens
M Mardirossian, R Sola, B Beckert, E Valencic, DWP Collis, J Borišek, ...
Journal of medicinal chemistry 63 (17), 9590-9602, 2020
352020
An antibiotic preorganized for ribosomal binding overcomes antimicrobial resistance
KJY Wu, BIC Tresco, A Ramkissoon, EV Aleksandrova, EA Syroegin, ...
Science 383 (6684), 721-726, 2024
222024
Structural basis for the inability of chloramphenicol to inhibit peptide bond formation in the presence of A-site glycine
EA Syroegin, EV Aleksandrova, YS Polikanov
Nucleic acids research 50 (13), 7669-7679, 2022
222022
Structure of dirithromycin bound to the bacterial ribosome suggests new ways for rational improvement of macrolides
NF Khabibullina, AG Tereshchenkov, ES Komarova, EA Syroegin, ...
Antimicrobial Agents and Chemotherapy 63 (6), 10.1128/aac. 02266-18, 2019
142019
Structural insights into the mechanism of overcoming Erm-mediated resistance by macrolides acting together with hygromycin-A
CW Chen, N Leimer, EA Syroegin, C Dunand, ZP Bulman, K Lewis, ...
Nature Communications 14 (1), 4196, 2023
102023
Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it
EV Aleksandrova, KJY Wu, BIC Tresco, EA Syroegin, EE Killeavy, ...
Nature Chemical Biology, 1-10, 2024
92024
Practical Synthesis of N-Formylmethionylated Peptidyl-tRNA Mimics
J Thaler, EA Syroegin, K Breuker, YS Polikanov, R Micura
ACS Chemical Biology 18 (10), 2233-2239, 2023
22023
Toxic small alarmone synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
T Kurata, M Takegawa, T Ohira, EA Syroegin, GC Atkinson, ...
Science Advances 10 (46), eadr9624, 2024
2024
Rationally Designed Pooled CRISPRi-Seq Uncovers an Inhibitor of Bacterial Peptidyl-tRNA Hydrolase
ASMZ Rahman, EA Syroegin, J Novomisky Nechcoff, A Devarajan, ...
bioRxiv, 2024.05. 02.592284, 2024
2024
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