Leptin-and leptin receptor-deficient rodent models: relevance for human type 2 diabetes B Wang, P Charukeshi Chandrasekera, J J Pippin Current diabetes reviews 10 (2), 131-145, 2014 | 589 | 2014 |
You are what you eat, or are you? The challenges of translating high-fat-fed rodents to human obesity and diabetes M Lai, PC Chandrasekera, ND Barnard Nutrition & diabetes 4 (9), e135-e135, 2014 | 152 | 2014 |
Of rodents and men: species-specific glucose regulation and type 2 diabetes research PC Chandrasekera, JJ Pippin ALTEX-Alternatives to animal experimentation 31 (2), 157-176, 2014 | 118 | 2014 |
Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities F Pistollato, EL Ohayon, A Lam, GR Langley, TJ Novak, D Pamies, ... Oncotarget 7 (26), 38999, 2016 | 81 | 2016 |
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, PC Chandrasekera, ... Altex 37 (4), 579, 2020 | 76 | 2020 |
Differential effects of adenosine A2a and A2b receptors on cardiac contractility PC Chandrasekera, VJ McIntosh, FX Cao, RD Lasley American Journal of Physiology-Heart and Circulatory Physiology 299 (6 …, 2010 | 68 | 2010 |
Knockout mouse models of insulin signaling: Relevance past and future AE Bunner, PC Chandrasekera, ND Barnard World journal of diabetes 5 (2), 146, 2014 | 63 | 2014 |
Animal-friendly affinity reagents: replacing the needless in the haystack AC Gray, SS Sidhu, PC Chandrasekera, CFM Hendriksen, ... Trends in Biotechnology 34 (12), 960-969, 2016 | 60 | 2016 |
Determination of apparent calcium affinity for endogenously expressed human sarco (endo) plasmic reticulum calcium-ATPase isoform SERCA3 PC Chandrasekera, ME Kargacin, JP Deans, J Lytton American Journal of Physiology-Cell Physiology 296 (5), C1105-C1114, 2009 | 56 | 2009 |
Adenosine A1 receptors heterodimerize with β1-and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling PC Chandrasekera, TC Wan, ET Gizewski, JA Auchampach, RD Lasley Cellular signalling 25 (4), 736-742, 2013 | 48 | 2013 |
Molecular signatures in protein sequences that are characteristic of cyanobacteria and plastid homologues RS Gupta, M Pereira, C Chandrasekera, V Johari International journal of systematic and evolutionary microbiology 53 (6 …, 2003 | 46 | 2003 |
Sex differences and the effects of ovariectomy on the β-adrenergic contractile response VJ McIntosh, PC Chandrasekera, RD Lasley American journal of physiology-Heart and Circulatory Physiology 301 (3 …, 2011 | 29 | 2011 |
A Human-Based Integrated Framework forAlzheimer’s Disease Research F Pistollato, SE Cavanaugh, PC Chandrasekera Journal of Alzheimer's disease 47 (4), 857-868, 2015 | 26 | 2015 |
Inhibition of human SERCA3 by PL/IM430: molecular analysis of the interaction CP Chandrasekera, J Lytton Journal of Biological Chemistry 278 (14), 12482-12488, 2003 | 26 | 2003 |
The human subject: an integrative animal model for 21st century heart failure research PC Chandrasekera, JJ Pippin American Journal of Translational Research 7 (9), 1636, 2015 | 22 | 2015 |
Animal research for type 2 diabetes mellitus, its limited translation for clinical benefit, and the way forward Z Ali, PC Chandrasekera, JJ Pippin Alternatives to Laboratory Animals 46 (1), 13-22, 2018 | 15 | 2018 |
Simulated breathing: application of molecular dynamics simulations to pulmonary lung surfactant M Dziura, B Mansour, M DiPasquale, PC Chandrasekera, JW Gauld, ... Symmetry 13 (7), 1259, 2021 | 12 | 2021 |
Advancing nonclinical innovation and safety in pharmaceutical testing EJ Baker, NA Beck, EL Berg, HD Clayton-Jeter, PC Chandrasekera, ... Drug Discovery Today 24 (2), 624-628, 2019 | 11 | 2019 |
Animal-based antibodies: Obsolete AC Gray, SS Sidhu, PC Chandrasekera, CFM Hendriksen, ... Science 353 (6298), 452-453, 2016 | 8 | 2016 |
Gender differences in the cardiac A1 adenosine receptor anti‐adrenergic effect VJ McIntosh, PC Chandrasekera, RD Lasley The FASEB Journal 24, 1041.5-1041.5, 2010 | 4 | 2010 |