Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases M Verbanck, CY Chen, B Neale, R Do Nature genetics 50 (5), 693-698, 2018 | 4454 | 2018 |
Mapping genomic loci implicates genes and synaptic biology in schizophrenia V Trubetskoy, AF Pardiñas, T Qi, G Panagiotaropoulou, S Awasthi, ... Nature 604 (7906), 502-508, 2022 | 1502* | 2022 |
Polygenic prediction via Bayesian regression and continuous shrinkage priors T Ge, CY Chen, Y Ni, YCA Feng, JW Smoller Nature communications 10 (1), 1776, 2019 | 1076 | 2019 |
FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 986 | 2023 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 972 | 2022 |
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences R Karlsson Linnér, P Biroli, E Kong, SFW Meddens, R Wedow, ... Nature genetics 51 (2), 245-257, 2019 | 614 | 2019 |
Assessment of bidirectional relationships between physical activity and depression among adults: a 2-sample Mendelian randomization study KW Choi, CY Chen, MB Stein, YC Klimentidis, MJ Wang, KC Koenen, ... JAMA psychiatry 76 (4), 399-408, 2019 | 569* | 2019 |
Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations RE Peterson, K Kuchenbaecker, RK Walters, CY Chen, AB Popejoy, ... Cell 179 (3), 589-603, 2019 | 542 | 2019 |
Comparative genetic architectures of schizophrenia in East Asian and European populations M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma, H Gaspar, M Ikeda, ... Nature genetics 51 (12), 1670-1678, 2019 | 526 | 2019 |
International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci CM Nievergelt, AX Maihofer, T Klengel, EG Atkinson, CY Chen, KW Choi, ... Nature communications 10 (1), 4558, 2019 | 472 | 2019 |
Largest GWAS of PTSD (N= 20 070) yields genetic overlap with schizophrenia and sex differences in heritability LE Duncan, A Ratanatharathorn, AE Aiello, LM Almli, AB Amstadter, ... Molecular psychiatry 23 (3), 666-673, 2018 | 464 | 2018 |
Improving polygenic prediction in ancestrally diverse populations Y Ruan, YF Lin, YCA Feng, CY Chen, M Lam, Z Guo, L He, A Sawa, ... Nature genetics 54 (5), 573-580, 2022 | 310 | 2022 |
Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank JD Szustakowski, S Balasubramanian, E Kvikstad, S Khalid, PG Bronson, ... Nature genetics 53 (7), 942-948, 2021 | 290 | 2021 |
Being overweight or obese and risk of developing rheumatoid arthritis among women: a prospective cohort study B Lu, LT Hiraki, JA Sparks, S Malspeis, CY Chen, JA Awosogba, ... Annals of the rheumatic diseases 73 (11), 1914-1922, 2014 | 267 | 2014 |
Phenome-wide heritability analysis of the UK Biobank T Ge, CY Chen, BM Neale, MR Sabuncu, JW Smoller PLoS genetics 13 (4), e1006711, 2017 | 241 | 2017 |
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan CJ Chen, LI Hsu, CH Wang, WL Shih, YH Hsu, MP Tseng, YC Lin, ... Toxicology and applied pharmacology 206 (2), 198-206, 2005 | 237 | 2005 |
Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries P Gharahkhani, E Jorgenson, P Hysi, AP Khawaja, S Pendergrass, X Han, ... Nature communications 12 (1), 1258, 2021 | 226 | 2021 |
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 2022 | 198 | 2022 |
Penetrance and pleiotropy of polygenic risk scores for schizophrenia in 106,160 patients across four health care systems AB Zheutlin, J Dennis, R Karlsson Linnér, A Moscati, N Restrepo, ... American Journal of Psychiatry 176 (10), 846-855, 2019 | 191 | 2019 |
Improved ancestry inference using weights from external reference panels CY Chen, S Pollack, DJ Hunter, JN Hirschhorn, P Kraft, AL Price Bioinformatics 29 (11), 1399-1406, 2013 | 185 | 2013 |