The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, ... Proceedings of the National Academy of Sciences 109 (15), E869-E878, 2012 | 586 | 2012 |
Delivering proteins for export from the cytosol BCS Cross, I Sinning, J Luirink, S High Nature reviews Molecular cell biology 10 (4), 255-264, 2009 | 235 | 2009 |
Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum BCS Cross, C McKibbin, AC Callan, P Roboti, M Piacenti, C Rabu, ... Journal of cell science 122 (23), 4393-4400, 2009 | 121 | 2009 |
RETRACTED: the unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling JA Cho, AH Lee, B Platzer, BCS Cross, BM Gardner, H De Luca, P Luong, ... Cell host & microbe 13 (5), 558-569, 2013 | 120 | 2013 |
Lifetime imaging of a fluorescent protein sensor reveals surprising stability of ER thiol redox E Avezov, BCS Cross, GSK Schierle, M Winters, HP Harding, EP Melo, ... The Journal of cell biology 201 (2), 337, 2013 | 104 | 2013 |
Specific transmembrane segments are selectively delayed at the ER translocon during opsin biogenesis N Ismail, SG Crawshaw, BCS Cross, AC Haagsma, S High Biochemical Journal 411 (3), 495-506, 2008 | 60 | 2008 |
Dual direction CRISPR transcriptional regulation screening uncovers gene networks driving drug resistance C le Sage, S Lawo, P Panicker, TME Scales, SA Rahman, AS Little, ... Scientific reports 7 (1), 17693, 2017 | 54 | 2017 |
Increasing the performance of pooled CRISPR–Cas9 drop-out screening BCS Cross, S Lawo, CR Archer, JR Hunt, JL Yarker, A Riccombeni, ... Scientific reports 6 (1), 31782, 2016 | 45 | 2016 |
Establishing a flow process to Coumarin‐8‐carbaldehydes as important synthetic scaffolds J Zak, D Ron, E Riva, HP Harding, BCS Cross, IR Baxendale Chemistry–A European Journal 18 (32), 9901-9910, 2012 | 44 | 2012 |
Selective inhibition of the unfolded protein response: targeting catalytic sites for Schiff base modification SM Tomasio, HP Harding, D Ron, BCS Cross, PJ Bond Molecular BioSystems 9 (10), 2408-2416, 2013 | 37 | 2013 |
Dissecting the physiological role of selective transmembrane-segment retention at the ER translocon BCS Cross, S High Journal of cell science 122 (11), 1768-1777, 2009 | 36 | 2009 |
The oligomeric state of Derlin-1 is modulated by endoplasmic reticulum stress SG Crawshaw, BCS Cross, CM Wilson, S High Molecular Membrane Biology 24 (2), 113-120, 2007 | 18 | 2007 |
Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors AC Bellail, HR Jin, HY Lo, SH Jung, C Hamdouchi, D Kim, RK Higgins, ... Science translational medicine 13 (615), eabh1486, 2021 | 17 | 2021 |
CRISPR-mediated transcriptional activation with synthetic guide RNA Ž Strezoska, SM Dickerson, E Maksimova, E Chou, MM Gross, K Hemphill, ... Journal of Biotechnology 319, 25-35, 2020 | 16* | 2020 |
CRISPR: a screener’s guide C le Sage, S Lawo, BCS Cross SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (3), 233-240, 2020 | 14 | 2020 |
Positional editing of transmembrane domains during ion channel assembly K Öjemalm, HR Watson, P Roboti, BCS Cross, J Warwicker, G von Heijne, ... Journal of Cell Science 126 (2), 464-472, 2013 | 14 | 2013 |
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein A Ray-Sinha, BCS Cross, A Mironov, E Wiertz, S High Molecular membrane biology 26 (8), 448-464, 2009 | 14 | 2009 |
A flexible, pooled CRISPR library for drug development screens M Blanck, MB Budnik-Zawilska, SR Lenger, JE McGonigle, GRA Martin, ... The CRISPR Journal 3 (3), 211-222, 2020 | 7 | 2020 |
New twists in the unfolded protein response BCS Cross, D Ron Elife 1, e00243, 2012 | 3 | 2012 |
Retraction notice to: The unfolded protein response element IRE1α senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling JA Cho, AH Lee, B Platzer, BCS Cross, BM Gardner, H De Luca, P Luong, ... Cell host & microbe 23 (4), 571, 2018 | 2 | 2018 |