A pan-serotype dengue virus inhibitor targeting the NS3–NS4B interaction SJF Kaptein, O Goethals, D Kiemel, A Marchand, B Kesteleyn, JF Bonfanti, ... Nature 598 (7881), 504-509, 2021 | 141 | 2021 |
Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing B Liu, S Chen, AL Rose, D Chen, F Cao, M Zwinderman, D Kiemel, ... Nucleic acids research 48 (2), 517-532, 2020 | 63 | 2020 |
Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates O Goethals, SJF Kaptein, B Kesteleyn, JF Bonfanti, L Van Wesenbeeck, ... Nature 615 (7953), 678-686, 2023 | 61 | 2023 |
Clementine juice has the potential for drug interactions–in vitro comparison with grapefruit and mandarin juice D Theile, N Hohmann, D Kiemel, G Gattuso, D Barreca, G Mikus, ... European Journal of Pharmaceutical Sciences 97, 247-256, 2017 | 44 | 2017 |
Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation D Kiemel, ASH Kroell, S Denolly, U Haselmann, JF Bonfanti, JI Andres, ... Nature Communications 15 (1), 6080, 2024 | 3 | 2024 |
nNOS-derived NO modulates force production and iNO-derived NO the excitability in C2C12-derived 3D tissue engineering skeletal muscle via different NO … M Mosqueira, LM Scheid, D Kiemel, T Richardt, M Rheinberger, D Ollech, ... Frontiers in Physiology 13, 946682, 2022 | 1 | 2022 |
Elucidation of the mechanism-of-action of highly potent Dengue virus NS4B inhibitors JNJ-A07 and JNJ-1802 D Kiemel | | 2024 |