Biochemical, cellular, and pharmacological aspects of the multidrug transporter SV Ambudkar, S Dey, CA Hrycyna, M Ramachandra, I Pastan, ... Annual review of pharmacology and toxicology 39 (1), 361-398, 1999 | 2785 | 1999 |
HIV-1 Protease Inhibitors Are Substrates for the MDR1 Multidrug Transporter CGL Lee, MM Gottesman, CO Cardarelli, M Ramachandra, KT Jeang, ... Biochemistry 37 (11), 3594-3601, 1998 | 590 | 1998 |
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein S Dey, M Ramachandra, I Pastan, MM Gottesman, SV Ambudkar Proceedings of the National Academy of Sciences 94 (20), 10594-10599, 1997 | 471 | 1997 |
Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5 M Kapoor, L Zhang, M Ramachandra, J Kusukawa, KE Ebner, ... Journal of Biological Chemistry 270 (32), 19100-19106, 1995 | 414 | 1995 |
Characterization of an extracellular lignin peroxidase of the lignocellulolytic actinomycete Streptomyces viridosporus M Ramachandra, DL Crawford, G Hertel Applied and Environmental Microbiology 54 (12), 3057-3063, 1988 | 365 | 1988 |
Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state M Ramachandra, SV Ambudkar, D Chen, CA Hrycyna, S Dey, ... Biochemistry 37 (14), 5010-5019, 1998 | 361 | 1998 |
Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes IW Cheney, STC Neuteboom, MT Vaillancourt, M Ramachandra, ... Cancer research 59 (10), 2318-2323, 1999 | 203 | 1999 |
Both ATP sites of human P-glycoprotein are essential but not symmetric CA Hrycyna, M Ramachandra, UA Germann, PW Cheng, I Pastan, ... Biochemistry 38 (42), 13887-13899, 1999 | 180 | 1999 |
Mechanism of action of human P-glycoprotein ATPase activity: photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two … CA Hrycyna, M Ramachandra, SV Ambudkar, YH Ko, PL Pedersen, ... Journal of Biological Chemistry 273 (27), 16631-16634, 1998 | 174 | 1998 |
Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy M Ramachandra, A Rahman, A Zou, M Vaillancourt, JA Howe, ... Nature biotechnology 19 (11), 1035-1041, 2001 | 170 | 2001 |
Extracellular Enzyme Activities during Lignocellulose Degradation by Streptomyces spp.: A Comparative Study of Wild-Type and Genetically Manipulated Strains M Ramachandra, DL Crawford, AL Pometto III Applied and Environmental Microbiology 53 (12), 2754-2760, 1987 | 166 | 1987 |
Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer L Xiao, A Parolia, Y Qiao, P Bawa, S Eyunni, R Mannan, SE Carson, ... Nature 601 (7893), 434-439, 2022 | 157 | 2022 |
Functional characterization of glycosylation-deficient human P-glycoprotein using a vaccinia virus expression system JJ Gribar, M Ramachandra, CA Hrycyna, S Dey, SV Ambudkar The Journal of membrane biology 173, 203-214, 2000 | 156 | 2000 |
Anti-PD-L1 peptide improves survival in sepsis Y Shindo, JS McDonough, KC Chang, M Ramachandra, PG Sasikumar, ... Journal of Surgical Research 208, 33-39, 2017 | 122 | 2017 |
Effect of ABC transporters on HIV‐1 infection: inhibition of virus production by the MDR1 transporter CGL LEE, M RAMACHANDRA, KTEH JEANG, MA MARTIN, IRA PASTAN, ... The FASEB Journal 14 (3), 516-522, 2000 | 114 | 2000 |
Calpain inhibitor 1 activates p53-dependent apoptosis in tumor cell lines IA Atencio, M Ramachandra, P Shabram, GW Demers | 104 | 2000 |
Evaluation of the Effects of Mitragyna speciosa Alkaloid Extract on Cytochrome P450 Enzymes Using a High Throughput Assay WM Kong, Z Chik, M Ramachandra, U Subramaniam, RER Aziddin, ... Molecules 16 (9), 7344-7356, 2011 | 102 | 2011 |
PD-1 derived CA-170 is an oral immune checkpoint inhibitor that exhibits preclinical anti-tumor efficacy PG Sasikumar, NS Sudarshan, S Adurthi, RK Ramachandra, DS Samiulla, ... Communications biology 4 (1), 699, 2021 | 100 | 2021 |
Advanced materials for wind turbine blade-A Review L Thomas, M Ramachandra Materials Today: Proceedings 5 (1), 2635-2640, 2018 | 97 | 2018 |
Small-molecule immune checkpoint inhibitors targeting PD-1/PD-L1 and other emerging checkpoint pathways PG Sasikumar, M Ramachandra BioDrugs 32 (5), 481-497, 2018 | 92 | 2018 |