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JIAN KANG
JIAN KANG
PhD
在 u.nus.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids
J Kang, L Lim, Y Lu, J Song
PLoS biology 17 (6), e3000327, 2019
1032019
Aicardi–Goutières syndrome protein TREX1 suppresses L1 and maintains genome integrity through exonuclease-independent ORF1p depletion
P Li, J Du, JL Goodier, J Hou, J Kang, HH Kazazian Jr, K Zhao, XF Yu
Nucleic acids research 45 (8), 4619-4631, 2017
872017
LINE1 contributes to autoimmunity through both RIG-I-and MDA5-mediated RNA sensing pathways
K Zhao, J Du, Y Peng, P Li, S Wang, Y Wang, J Hou, J Kang, W Zheng, ...
Journal of autoimmunity 90, 105-115, 2018
832018
ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS
J Kang, L Lim, J Song
Biochemical and biophysical research communications 504 (2), 545-551, 2018
732018
ATP binds and inhibits the neurodegeneration-associated fibrillization of the FUS RRM domain
J Kang, L Lim, J Song
Communications biology 2 (1), 223, 2019
652019
Analysis of enterovirus 68 strains from the 2014 North American outbreak reveals a new clade, indicating viral evolution
J Du, B Zheng, W Zheng, P Li, J Kang, J Hou, R Markham, K Zhao, XF Yu
PloS one 10 (12), e0144208, 2015
592015
TDP-43 NTD can be induced while CTD is significantly enhanced by ssDNA to undergo liquid-liquid phase separation
L Wang, J Kang, L Lim, Y Wei, J Song
Biochemical and biophysical research communications 499 (2), 189-195, 2018
452018
ATP is a cryptic binder of TDP-43 RRM domains to enhance stability and inhibit ALS/AD-associated fibrillation
M Dang, J Kang, L Lim, Y Li, L Wang, J Song
Biochemical and Biophysical Research Communications 522 (1), 247-253, 2020
362020
Structurally-and dynamically-driven allostery of the chymotrypsin-like proteases of SARS, Dengue and Zika viruses
L Lim, G Gupta, A Roy, J Kang, S Srivastava, J Shi, J Song
Progress in Biophysics and Molecular Biology 143, 52-66, 2019
272019
Evolutionarily conserved pressure for the existence of distinct G2/M cell cycle arrest and A3H inactivation functions in HIV-1 Vif
K Zhao, J Du, Y Rui, W Zheng, J Kang, J Hou, K Wang, W Zhang, ...
Cell cycle 14 (6), 838-847, 2015
262015
ATP biphasically modulates LLPS of TDP-43 PLD by specifically binding arginine residues
M Dang, L Lim, J Kang, J Song
Communications Biology 4 (1), 714, 2021
252021
Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression
X Zhou, X Han, K Zhao, J Du, SL Evans, H Wang, P Li, W Zheng, Y Rui, ...
Journal of virology 88 (5), 2555-2563, 2014
232014
ATP antagonizes the crowding-induced destabilization of the human eye-lens protein γS-crystallin
Y He, J Kang, J Song
Biochemical and biophysical research communications 526 (4), 1112-1117, 2020
212020
ALS-causing profilin-1-mutant forms a non-native helical structure in membrane environments
L Lim, J Kang, J Song
Biochimica et Biophysica Acta (BBA)-Biomembranes 1859 (11), 2161-2170, 2017
202017
ATP binds nucleic-acid-binding domains beyond RRM fold
Y He, J Kang, L Lim, J Song
Biochemical and Biophysical Research Communications 522 (4), 826-831, 2020
102020
Vif-CBFβ interaction is essential for Vif-induced cell cycle arrest
J Du, Y Rui, W Zheng, P Li, J Kang, K Zhao, T Sun, XF Yu
Biochemical and biophysical research communications 511 (4), 910-915, 2019
92019
TMEM106B, a risk factor for FTLD and aging, has an intrinsically disordered cytoplasmic domain
J Kang, L Lim, J Song
PloS one 13 (10), e0205856, 2018
82018
Cataract-causing G18V eliminates the antagonization by ATP against the crowding-induced destabilization of human γS-crystallin
Y He, J Kang, J Song
Biochemical and Biophysical Research Communications 530 (3), 554-560, 2020
62020
ATP regulates TDP-43 pathogenesis by specifically binding to an inhibitory component of a delicate network controlling LLPS
D Mei, L Lim, J Kang, J Song
BioRxiv, 2020.10. 08.330829, 2020
42020
Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis
J Zhang, Z Hu, HH Chung, Y Tian, KW Lau, Z Ser, YT Lim, RM Sobota, ...
Nature Communications 14 (1), 2439, 2023
32023
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