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David J. Huss
David J. Huss
Chief Scientific Officer, Shape Therapeutics
在 shapetx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
T-bet is essential for encephalitogenicity of both Th1 and Th17 cells
Y Yang, J Weiner, Y Liu, AJ Smith, DJ Huss, R Winger, H Peng, ...
Journal of Experimental Medicine 206 (7), 1549-1564, 2009
3522009
Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor κB (NF-κB) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated …
H Peng, M Guerau-de-Arellano, VB Mehta, Y Yang, DJ Huss, ...
Journal of Biological Chemistry 287 (33), 28017-28026, 2012
2232012
DMF, but not other fumarates, inhibits NF-κB activity in vitro in an Nrf2-independent manner
GO Gillard, B Collette, J Anderson, J Chao, RH Scannevin, DJ Huss, ...
Journal of neuroimmunology 283, 74-85, 2015
1882015
Imaging CAR T cell therapy with PSMA-targeted positron emission tomography
I Minn, DJ Huss, HH Ahn, TM Chinn, A Park, J Jones, M Brummet, ...
Science advances 5 (7), eaaw5096, 2019
1162019
TGF‐β signaling via Smad4 drives IL‐10 production in effector Th1 cells and reduces T‐cell trafficking in EAE
DJ Huss, RC Winger, GM Cox, M Guerau‐de‐Arellano, Y Yang, ...
European journal of immunology 41 (10), 2987-2996, 2011
732011
TGF-β enhances effector Th1 cell activation but promotes self-regulation via IL-10
DJ Huss, RC Winger, H Peng, Y Yang, MK Racke, AE Lovett-Racke
The Journal of Immunology 184 (10), 5628-5636, 2010
652010
In vivo maintenance of human regulatory T cells during CD25 blockade
DJ Huss, DS Mehta, A Sharma, X You, KA Riester, JP Sheridan, ...
The Journal of Immunology 194 (1), 84-92, 2015
522015
RNA editing: Expanding the potential of RNA therapeutics
BJ Booth, S Nourreddine, D Katrekar, Y Savva, D Bose, TJ Long, DJ Huss, ...
Molecular Therapy 31 (6), 1533-1549, 2023
512023
Anti‐CD 25 monoclonal antibody Fc variants differentially impact regulatory T cells and immune homeostasis
DJ Huss, AF Pellerin, BP Collette, AK Kannan, L Peng, A Datta, BT Wipke, ...
Immunology 148 (3), 276-286, 2016
392016
Circulating innate lymphoid cells are unchanged in response to DAC HYP therapy
GO Gillard, SA Saenz, DJ Huss, JD Fontenot
Journal of neuroimmunology 294, 41-45, 2016
192016
How cognitive models can inform the design of instructions
NA Taatgen, D Huss, JR Anderson
Proceedings of the seventh international conference on cognitive modeling …, 2006
122006
Dimethyl fumarate and monomethyl fumarate are distinguished by non-overlapping pharmacodynamic effects in vivo (P1. 206)
M Brennan, N Allaire, D Huss, P Cullen, A Thai, S Szak, A Thomas, ...
Neurology 82 (10_supplement), P1. 206, 2014
82014
A novel role for Kv1. 3 blockers: protecting neural progenitor cells from a hostile inflammatory environment
H Peng, DJ Huss
Journal of Neuroscience 30 (32), 10609-10611, 2010
62010
Instructional Representation in cognitive modeling
D Huss, NA Taatgen, JR Anderson
Proceedings of the Seventh International Conference on Cognitive Modeling …, 2006
32006
DMF treatment prevents cellular infiltration and reduces the frequency of IFN [gamma]-positive CD4-T-lymphocytes in EAE spinal cords
P Bista, A Thomas, K Fu, W Zeng, MN Shackett, D Huss, Y Luo, ...
MULTIPLE SCLEROSIS JOURNAL 18, 357-358, 2012
12012
Prodrugs and drugs
J Fontenot, D Huss, RH Scannevin, K Rhodes
US Patent App. 14/892,839, 2016
2016
In Vivo Maintenance of Human Regulatory T
LS Amaravadi, JS Elkins, JDX You, KA Riester, JP Sheridan, DJ Huss, ...
2014
Characterization of CD56bright NK cells in Daclizumab HYP-treated RRMS patients
DJ Huss, MF Fragoso, P Cullen, N Allaire, JD Fontenot
Journal of Neuroimmunology 275 (1), 86, 2014
2014
CD25 blockade with daclizumab alters regulatory T cell dynamics in RRMS patients (THER3P. 880)
D Huss, D Mehta, A Sharma, X You, K Riester, J Sheridan, L Amaravadi, ...
The Journal of Immunology 192 (1_Supplement), 136.6-136.6, 2014
2014
Fumarate Esters Are Distinguished by Differential Inhibition of the NF-κB Mediated Proinflammatory Response.(P1. 205)
G Gillard, D Huss, J Anderson, B Collette, A Bertolotti-Ciarlet, ...
Neurology 82 (10_supplement), P1. 205, 2014
2014
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