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Nico Lingg
Nico Lingg
Senior Scientist, Austrian Centre of Industrial Biotechnology
在 acib.at 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
The sweet tooth of biopharmaceuticals: importance of recombinant protein glycosylation analysis
N Lingg, P Zhang, Z Song, M Bardor
Biotechnology journal 7 (12), 1462-1472, 2012
1182012
Charge heterogeneity: basic antibody charge variants with increased binding to Fc receptors
B Hintersteiner, N Lingg, P Zhang, S Woen, KM Hoi, S Stranner, ...
MAbs 8 (8), 1548-1560, 2016
902016
Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor
N Hammerschmidt, B Hintersteiner, N Lingg, A Jungbauer
Biotechnology Journal 10 (8), 1196-1205, 2015
772015
Microheterogeneity of recombinant antibodies: analytics and functional impact
B Beyer, M Schuster, A Jungbauer, N Lingg
Biotechnology journal 13 (1), 1700476, 2018
732018
Microheterogeneity of therapeutic monoclonal antibodies is governed by changes in the surface charge of the protein
B Hintersteiner, N Lingg, E Janzek, O Mutschlechner, H Loibner, ...
Biotechnology journal 11 (12), 1617-1627, 2016
542016
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range
N Lingg, E Tan, B Hintersteiner, M Bardor, A Jungbauer
Journal of Chromatography A 1319, 65-71, 2013
502013
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests
M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ...
EBioMedicine 67, 2021
432021
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range: validation of the method parameters
N Lingg, M Berndtsson, B Hintersteiner, M Schuster, M Bardor, ...
Journal of Chromatography A 1373, 124-130, 2014
352014
Impact of mammalian cell culture conditions on monoclonal antibody charge heterogeneity: an accessory monitoring tool for process development
B Sissolak, N Lingg, W Sommeregger, G Striedner, K Vorauer-Uhl
Journal of Industrial Microbiology and Biotechnology 46 (8), 1167-1178, 2019
272019
Production of Circularly Permuted Caspase-2 for Affinity Fusion-Tag Removal: Cloning, Expression in Escherichia coli, Purification, and Characterization
M Cserjan-Puschmann, N Lingg, P Engele, C Kröß, J Loibl, A Fischer, ...
Biomolecules 10 (12), 1592, 2020
242020
Change of charge variant composition of trastuzumab upon stressing at physiological conditions
B Spanov, O Olaleye, N Lingg, AEH Bentlage, N Govorukhina, J Hermans, ...
Journal of Chromatography A 1655, 462506, 2021
232021
Fusion Tag Design Influences Soluble Recombinant Protein Production in Escherichia coli
C Köppl, N Lingg, A Fischer, C Kröß, J Loibl, W Buchinger, R Schneider, ...
International Journal of Molecular Sciences 23 (14), 7678, 2022
212022
How similar is biosimilar? A comparison of infliximab therapeutics in regard to charge variant profile and antigen binding affinity
B Beyer, N Walch, A Jungbauer, N Lingg
Biotechnology Journal 14 (4), 1800340, 2019
192019
Proteomics analysis of host cell proteins after immobilized metal affinity chromatography: Influence of ligand and metal ions
N Lingg, C Öhlknecht, A Fischer, M Mozgovicz, T Scharl, C Oostenbrink, ...
Journal of Chromatography A 1633, 461649, 2020
172020
CASPON platform technology: Ultrafast circularly permuted caspase-2 cleaves tagged fusion proteins before all 20 natural amino acids at the N-terminus
N Lingg, C Kröß, P Engele, C Öhlknecht, C Köppl, A Fischer, B Lier, ...
New Biotechnology 71, 37-46, 2022
132022
Advanced purification platform using circularly permuted caspase‐2 for affinity fusion‐tag removal to produce native fibroblast growth factor 2
N Lingg, M Cserjan‐Puschmann, A Fischer, P Engele, C Kröß, ...
Journal of Chemical Technology & Biotechnology 96 (6), 1515-1522, 2021
112021
In-situ gradient formation by direct solid addition of buffer components
D Komuczki, N Lingg, A Jungbauer, P Satzer
Journal of Chromatography A 1634, 461663, 2020
112020
Hydrophobic interaction chromatography as polishing step enables obtaining ultra-pure recombinant antibodies
IRAP Bresolin, N Lingg, ITL Bresolin, A Jungbauer
Journal of Biotechnology 324, 100020, 2020
112020
Productivity for free: Residence time gradients during loading increase dynamic binding capacity and productivity
T Eslami, LA Jakob, P Satzer, G Ebner, A Jungbauer, N Lingg
Separation and Purification Technology 281, 119985, 2022
102022
Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light …
J De Vos, PP Aguilar, C Köppl, A Fischer, C Grünwald-Gruber, M Dürkop, ...
Talanta 235, 122691, 2021
92021
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