The sweet tooth of biopharmaceuticals: importance of recombinant protein glycosylation analysis N Lingg, P Zhang, Z Song, M Bardor Biotechnology journal 7 (12), 1462-1472, 2012 | 118 | 2012 |
Charge heterogeneity: basic antibody charge variants with increased binding to Fc receptors B Hintersteiner, N Lingg, P Zhang, S Woen, KM Hoi, S Stranner, ... MAbs 8 (8), 1548-1560, 2016 | 90 | 2016 |
Continuous precipitation of IgG from CHO cell culture supernatant in a tubular reactor N Hammerschmidt, B Hintersteiner, N Lingg, A Jungbauer Biotechnology Journal 10 (8), 1196-1205, 2015 | 77 | 2015 |
Microheterogeneity of recombinant antibodies: analytics and functional impact B Beyer, M Schuster, A Jungbauer, N Lingg Biotechnology journal 13 (1), 1700476, 2018 | 73 | 2018 |
Microheterogeneity of therapeutic monoclonal antibodies is governed by changes in the surface charge of the protein B Hintersteiner, N Lingg, E Janzek, O Mutschlechner, H Loibner, ... Biotechnology journal 11 (12), 1617-1627, 2016 | 54 | 2016 |
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range N Lingg, E Tan, B Hintersteiner, M Bardor, A Jungbauer Journal of Chromatography A 1319, 65-71, 2013 | 50 | 2013 |
A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests M Klausberger, M Duerkop, H Haslacher, G Wozniak-Knopp, ... EBioMedicine 67, 2021 | 43 | 2021 |
Highly linear pH gradients for analyzing monoclonal antibody charge heterogeneity in the alkaline range: validation of the method parameters N Lingg, M Berndtsson, B Hintersteiner, M Schuster, M Bardor, ... Journal of Chromatography A 1373, 124-130, 2014 | 35 | 2014 |
Impact of mammalian cell culture conditions on monoclonal antibody charge heterogeneity: an accessory monitoring tool for process development B Sissolak, N Lingg, W Sommeregger, G Striedner, K Vorauer-Uhl Journal of Industrial Microbiology and Biotechnology 46 (8), 1167-1178, 2019 | 27 | 2019 |
Production of Circularly Permuted Caspase-2 for Affinity Fusion-Tag Removal: Cloning, Expression in Escherichia coli, Purification, and Characterization M Cserjan-Puschmann, N Lingg, P Engele, C Kröß, J Loibl, A Fischer, ... Biomolecules 10 (12), 1592, 2020 | 24 | 2020 |
Change of charge variant composition of trastuzumab upon stressing at physiological conditions B Spanov, O Olaleye, N Lingg, AEH Bentlage, N Govorukhina, J Hermans, ... Journal of Chromatography A 1655, 462506, 2021 | 23 | 2021 |
Fusion Tag Design Influences Soluble Recombinant Protein Production in Escherichia coli C Köppl, N Lingg, A Fischer, C Kröß, J Loibl, W Buchinger, R Schneider, ... International Journal of Molecular Sciences 23 (14), 7678, 2022 | 21 | 2022 |
How similar is biosimilar? A comparison of infliximab therapeutics in regard to charge variant profile and antigen binding affinity B Beyer, N Walch, A Jungbauer, N Lingg Biotechnology Journal 14 (4), 1800340, 2019 | 19 | 2019 |
Proteomics analysis of host cell proteins after immobilized metal affinity chromatography: Influence of ligand and metal ions N Lingg, C Öhlknecht, A Fischer, M Mozgovicz, T Scharl, C Oostenbrink, ... Journal of Chromatography A 1633, 461649, 2020 | 17 | 2020 |
CASPON platform technology: Ultrafast circularly permuted caspase-2 cleaves tagged fusion proteins before all 20 natural amino acids at the N-terminus N Lingg, C Kröß, P Engele, C Öhlknecht, C Köppl, A Fischer, B Lier, ... New Biotechnology 71, 37-46, 2022 | 13 | 2022 |
Advanced purification platform using circularly permuted caspase‐2 for affinity fusion‐tag removal to produce native fibroblast growth factor 2 N Lingg, M Cserjan‐Puschmann, A Fischer, P Engele, C Kröß, ... Journal of Chemical Technology & Biotechnology 96 (6), 1515-1522, 2021 | 11 | 2021 |
In-situ gradient formation by direct solid addition of buffer components D Komuczki, N Lingg, A Jungbauer, P Satzer Journal of Chromatography A 1634, 461663, 2020 | 11 | 2020 |
Hydrophobic interaction chromatography as polishing step enables obtaining ultra-pure recombinant antibodies IRAP Bresolin, N Lingg, ITL Bresolin, A Jungbauer Journal of Biotechnology 324, 100020, 2020 | 11 | 2020 |
Productivity for free: Residence time gradients during loading increase dynamic binding capacity and productivity T Eslami, LA Jakob, P Satzer, G Ebner, A Jungbauer, N Lingg Separation and Purification Technology 281, 119985, 2022 | 10 | 2022 |
Production of full-length SARS-CoV-2 nucleocapsid protein from Escherichia coli optimized by native hydrophobic interaction chromatography hyphenated to multi-angle light … J De Vos, PP Aguilar, C Köppl, A Fischer, C Grünwald-Gruber, M Dürkop, ... Talanta 235, 122691, 2021 | 9 | 2021 |