Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression A Le, CR Cooper, AM Gouw, R Dinavahi, A Maitra, LM Deck, RE Royer, ... Proceedings of the National Academy of Sciences 107 (5), 2037-2042, 2010 | 1537 | 2010 |
MYC regulates the antitumor immune response through CD47 and PD-L1 SC Casey, L Tong, Y Li, R Do, S Walz, KN Fitzgerald, AM Gouw, V Baylot, ... Science 352 (6282), 227-231, 2016 | 1255 | 2016 |
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ... Cell metabolism 15 (1), 110-121, 2012 | 1195 | 2012 |
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ... The Journal of clinical investigation 125 (6), 2293-2306, 2015 | 470 | 2015 |
The MYC oncogene—the grand orchestrator of cancer growth and immune evasion R Dhanasekaran, A Deutzmann, WD Mahauad-Fernandez, AS Hansen, ... Nature Reviews Clinical Oncology 19 (1), 23-36, 2022 | 418 | 2022 |
The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma H Miess, B Dankworth, AM Gouw, M Rosenfeldt, W Schmitz, M Jiang, ... Oncogene 37 (40), 5435-5450, 2018 | 290 | 2018 |
MYC disrupts the circadian clock and metabolism in cancer cells BJ Altman, AL Hsieh, A Sengupta, SY Krishnanaiah, ZE Stine, ZE Walton, ... Cell metabolism 22 (6), 1009-1019, 2015 | 276 | 2015 |
MYC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism EH Shroff, LS Eberlin, VM Dang, AM Gouw, M Gabay, SJ Adam, ... Proceedings of the National Academy of Sciences 112 (21), 6539-6544, 2015 | 272 | 2015 |
Age-related decline of sleep-dependent consolidation RMC Spencer, AM Gouw, RB Ivry Learning & Memory 14 (7), 480-484, 2007 | 255 | 2007 |
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice L Cui, AM Gouw, EL LaGory, S Guo, N Attarwala, Y Tang, J Qi, YS Chen, ... Nature Biotechnology, 1-11, 2020 | 219 | 2020 |
The MYC oncogene cooperates with sterol-regulated element-binding protein to regulate lipogenesis essential for neoplastic growth AM Gouw, K Margulis, NS Liu, SJ Raman, A Mancuso, GG Toal, L Tong, ... Cell metabolism 30 (3), 556-572. e5, 2019 | 154 | 2019 |
Alteration of the lipid profile in lymphomas induced by MYC overexpression LS Eberlin, M Gabay, AC Fan, AM Gouw, RJ Tibshirani, DW Felsher, ... Proceedings of the National Academy of Sciences 111 (29), 10450-10455, 2014 | 145 | 2014 |
Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma AM Gouw, LS Eberlin, K Margulis, DK Sullivan, GG Toal, L Tong, RN Zare, ... Proceedings of the National Academy of Sciences 114 (17), 4300-4305, 2017 | 135 | 2017 |
MYC regulates the HIF2α stemness pathway via Nanog and Sox2 to maintain self-renewal in cancer stem cells versus non-stem cancer cells B Das, B Pal, R Bhuyan, H Li, A Sarma, S Gayan, J Talukdar, S Sandhya, ... Cancer research 79 (16), 4015-4025, 2019 | 85 | 2019 |
Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia–cell cycle dual reporter A Le, ZE Stine, C Nguyen, J Afzal, P Sun, M Hamaker, NM Siegel, ... Proceedings of the National Academy of Sciences 111 (34), 12486-12491, 2014 | 68 | 2014 |
p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia A Yetil, B Anchang, AM Gouw, SJ Adam, T Zabuawala, R Parameswaran, ... Oncotarget 6 (6), 3563, 2015 | 28 | 2015 |
Future space missions and human enhancement: Medical and ethical challenges K Szocik, M Shelhamer, M Braddock, FA Cucinotta, C Impey, P Worden, ... Futures 133, 102819, 2021 | 22 | 2021 |
Engaging a community for rare genetic disease: best practices and education from individual crowdfunding campaigns RA Ortiz, S Witte, A Gouw, A Sanfilippo, R Tsai, D Fumagalli, C Yu, K Lant, ... Interactive journal of medical research 7 (1), e7176, 2018 | 20 | 2018 |
Deregulation of the cellular energetics of cancer cells ZE Stine, BJ Altman, AL Hsieh, AM Gouw, CV Dang Pathobiology of Human Disease: A Dynamic Encyclopedia of Disease Mechanisms …, 2014 | 20 | 2014 |
MYC oncogene elicits tumorigenesis associated with embryonic, ribosomal biogenesis, and tissue-lineage dedifferentiation gene expression changes DK Sullivan, A Deutzmann, J Yarbrough, MS Krishnan, AM Gouw, ... Oncogene 41 (45), 4960-4970, 2022 | 18 | 2022 |