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Whasil Lee
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Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage
W Lee, HA Leddy, Y Chen, SH Lee, NA Zelenski, AL McNulty, J Wu, ...
Proceedings of the National Academy of Sciences 111 (47), E5114-E5122, 2014
4302014
UVA generates pyrimidine dimers in DNA directly
Y Jiang, M Rabbi, M Kim, C Ke, W Lee, RL Clark, PA Mieczkowski, ...
Biophysical journal 96 (3), 1151-1158, 2009
2082009
Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis
W Lee, RJ Nims, A Savadipour, Q Zhang, HA Leddy, F Liu, AL McNulty, ...
Proceedings of the National Academy of Sciences 118 (13), e2001611118, 2021
1482021
TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor
Y Chen, P Kanju, Q Fang, SH Lee, PK Parekh, W Lee, C Moore, ...
Pain 155 (12), 2662-2672, 2014
832014
Role of piezo channels in joint health and injury
W Lee, F Guilak, W Liedtke
Current topics in membranes 79, 263-273, 2017
812017
Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain
P Kanju, Y Chen, W Lee, M Yeo, SH Lee, J Romac, R Shahid, P Fan, ...
Scientific reports 6 (1), 26894, 2016
732016
Fast and forceful refolding of stretched α-helical solenoid proteins
M Kim, K Abdi, G Lee, M Rabbi, W Lee, M Yang, CJ Schofield, V Bennett, ...
Biophysical journal 98 (12), 3086-3092, 2010
642010
Mechanical unfolding of an ankyrin repeat protein
D Serquera, W Lee, G Settanni, PE Marszalek, E Paci, LS Itzhaki
Biophysical journal 98 (7), 1294-1301, 2010
562010
Full reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations
W Lee, X Zeng, HX Zhou, V Bennett, W Yang, PE Marszalek
Journal of Biological Chemistry 285 (49), 38167-38172, 2010
492010
The role of mechanically-activated ion channels Piezo1, Piezo2, and TRPV4 in chondrocyte mechanotransduction and mechano-therapeutics for osteoarthritis
W Gao, H Hasan, DE Anderson, W Lee
Frontiers in Cell and Developmental Biology 10, 885224, 2022
362022
Molecular manipulation with atomic force microscopy
AS Duwez, N Willet
CRC Press, 2011
282011
Mechanical anisotropy of ankyrin repeats
W Lee, X Zeng, K Rotolo, M Yang, CJ Schofield, V Bennett, W Yang, ...
Biophysical journal 102 (5), 1118-1126, 2012
262012
Minimizing pulling geometry errors in atomic force microscope single molecule force spectroscopy
M Rivera, W Lee, C Ke, PE Marszalek, DG Cole, RL Clark
Biophysical journal 95 (8), 3991-3998, 2008
192008
Mutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats
W Lee, J Strümpfer, V Bennett, K Schulten, PE Marszalek
Journal of Biological Chemistry 287 (23), 19115-19121, 2012
132012
Hydrogel swelling-mediated strain induces cell alignment at dentin interfaces
D Fraser, T Nguyen, A Kotelsky, W Lee, M Buckley, DSW Benoit
ACS Biomaterials Science & Engineering 8 (8), 3568-3575, 2022
102022
Mechanics of polysaccharides
W Lee, X Zeng, W Yang, PE Marszalek
Molecular manipulation with atomic force microscopy, 2012
92012
Effect of knee joint loading on chondrocyte mechano-vulnerability and severity of post-traumatic osteoarthritis induced by ACL-injury in mice
A Kotelsky, A Elahi, CN Yigit, A Proctor, S Mannava, C Pröschel, W Lee
Osteoarthritis and Cartilage Open 4 (1), 100227, 2022
42022
Osteoarthritis: articular chondrocyte inflammatory signaling leads to enhanced gene expression and function of mechanotransduction channel Piezo1 as a pathogenic feed-forward …
W Lee, RJ Nims, A Savadipour, H Leddy, F Liu, A McNulty, Y Chen, ...
bioRxiv, 2020.05. 23.112565, 2020
22020
Nanomechanics of Ankyrin Repeat Proteins
W Lee
Ph. D. thesis, Duke University, 2011
12011
Nanomechanics of Ankyrin-R Repeats Probed by AFM and SMD Simulations
W Lee, M Yang, CJ Schofield, PE Marszalek
Biophysical Journal 98 (3), 447a, 2010
12010
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