Apolipoprotein E: structural insights and links to Alzheimer disease pathogenesis Y Chen, MR Strickland, A Soranno, DM Holtzman Neuron 109 (2), 205-221, 2021 | 169 | 2021 |
Microglia-specific targeting by novel capsid-modified AAV6 vectors AM Rosario, PE Cruz, C Ceballos-Diaz, MR Strickland, Z Siemienski, ... Molecular Therapy Methods & Clinical Development 3, 2016 | 125 | 2016 |
Activated microglia mitigate Aβ-associated tau seeding and spreading M Gratuze, Y Chen, S Parhizkar, N Jain, MR Strickland, JR Serrano, ... Journal of Experimental Medicine 218 (8), e20210542, 2021 | 119 | 2021 |
TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer’s disease P Chakrabarty, A Li, TB Ladd, MR Strickland, EJ Koller, JD Burgess, ... Journal of Experimental Medicine 215 (9), 2247-2264, 2018 | 57 | 2018 |
Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1‐42 DL Kober, MD Stuchell‐Brereton, CE Kluender, HB Dean, MR Strickland, ... Alzheimer's & Dementia 17 (3), 475-488, 2021 | 52 | 2021 |
Role of the L-PGDS-PGD2-DP1 receptor axis in sleep regulation and neurologic outcomes AS Ahmad, H Ottallah, CB Maciel, M Strickland, S Doré Sleep 42 (6), zsz073, 2019 | 30 | 2019 |
Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol AG Cashikar, D Toral-Rios, D Timm, J Romero, M Strickland, JM Long, ... Journal of lipid research 64 (4), 2023 | 22 | 2023 |
APOE3ch alters microglial response and suppresses Aβ-induced tau seeding and spread Y Chen, S Song, S Parhizkar, J Lord, Y Zhu, MR Strickland, C Wang, ... Cell 187 (2), 428-445. e20, 2024 | 21 | 2024 |
Ifngr1 and Stat1 mediated canonical Ifn-γ signaling drives nigrostriatal degeneration MR Strickland, EJ Koller, DZ Deng, C Ceballos-Diaz, TE Golde, ... Neurobiology of disease 110, 133-141, 2018 | 15 | 2018 |
APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading C Wang, A Nambiar, MR Strickland, C Lee, S Parhizkar, AC Moore, ... The Journal of Clinical Investigation 133 (14), 2023 | 11 | 2023 |
Dr. Jekyll and Mr. Hyde: ApoE explains opposing effects of neuronal LRP1 MR Strickland, DM Holtzman The Journal of clinical investigation 129 (3), 969-971, 2019 | 10 | 2019 |
IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis MR Strickland, KR Ibanez, M Yaroshenko, CC Diaz, DR Borchelt, ... Scientific Reports 10 (1), 20862, 2020 | 7 | 2020 |
Cell autonomous role of border associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury C Iadecola, A Anfray, S Schaeffer, Y Hattori, M Santisteban, N Casey, ... Research Square, 2023 | 5 | 2023 |
Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy D Toral-Rios, JM Long, JD Ulrich, J Yu, MR Strickland, X Han, ... Journal of Experimental Medicine 221 (4), e20232000, 2024 | 3 | 2024 |
ApoE isoforms differentially regulate neuronal membrane proteasomes to shift the threshold for pathological aggregation of endogenous Tau V Paradise, M Sabu, J Bafia, NA Sharif, C Nguyen, MR Dhanraj, X Wang, ... Biorxiv, 2022 | 3* | 2022 |
Apolipoprotein E secreted by astrocytes forms antiparallel dimers in discoidal lipoproteins MR Strickland, MJ Rau, B Summers, K Basore, J Wulf, H Jiang, Y Chen, ... Neuron 112 (7), 1100-1109. e5, 2024 | 2 | 2024 |
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease Z Xia, EE Prescott, A Urbanek, HE Wareing, MC King, A Olerinyova, ... Nature Communications 15 (1), 4695, 2024 | 1 | 2024 |
APOE3 Christchurch influences amyloid induced tau seeding and spreading via effects on microglia Y Chen, S Song, S Parhizkar, J Lord, Y Zhu, MR Strickland, C Wang, ... Alzheimer's Association International Conference, 2024 | | 2024 |
Apolipoprotein E Registry In Discoidal Lipoproteins Influences Uptake MR Strickland, B Summers, K Basore, J Wulf, H Jiang, MG Sorci Thomas, ... Arteriosclerosis, Thrombosis, and Vascular Biology 44 (Suppl_1), A116-A116, 2024 | | 2024 |
Microglial 25-hydroxycholesterol mediates neuroinflammation and neurodegeneration in a tauopathy mouse model D Toral-Rios, JM Long, JD Ulrich, J Yu, MR Strickland, X Han, ... bioRxiv, 2023.09. 08.556884, 2023 | | 2023 |