Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis J Rejman, V Oberle, IS Zuhorn, D Hoekstra Biochemical journal 377 (1), 159-169, 2004 | 3353 | 2004 |
Ultrasound and microbubble-targeted delivery of macromolecules is regulated by induction of endocytosis and pore formation BDM Meijering, LJM Juffermans, A van Wamel, RH Henning, IS Zuhorn, ... Circulation research 104 (5), 679-687, 2009 | 513 | 2009 |
Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis IS Zuhorn, R Kalicharan, D Hoekstra Journal of Biological Chemistry 277 (20), 18021-18028, 2002 | 439 | 2002 |
Mechanism of polyplex-and lipoplex-mediated delivery of nucleic acids: real-time visualization of transient membrane destabilization without endosomal lysis Z Rehman, D Hoekstra, IS Zuhorn ACS nano 7 (5), 3767-3777, 2013 | 391 | 2013 |
Endocytosis of extracellular vesicles and release of their cargo from endosomes BS Joshi, MA de Beer, BNG Giepmans, IS Zuhorn ACS nano 14 (4), 4444-4455, 2020 | 342 | 2020 |
Nonbilayer phase of lipoplex–membrane mixture determines endosomal escape of genetic cargo and transfection efficiency IS Zuhorn, U Bakowsky, E Polushkin, WH Visser, MCA Stuart, ... Molecular therapy 11 (5), 801-810, 2005 | 329 | 2005 |
Carriers break barriers in drug delivery: endocytosis and endosomal escape of gene delivery vectors IMS Degors, C Wang, ZU Rehman, IS Zuhorn Accounts of chemical research 52 (7), 1750-1760, 2019 | 310 | 2019 |
Gene delivery by cationic lipid vectors: overcoming cellular barriers IS Zuhorn, JBFN Engberts, D Hoekstra European Biophysics Journal 36, 349-362, 2007 | 309 | 2007 |
A sensor for quantification of macromolecular crowding in living cells AJ Boersma, B Liu, B Poolman Biophysical Journal 108 (2), 114a, 2015 | 238 | 2015 |
Surface characteristics of nanoparticles determine their intracellular fate in and processing by human blood–brain barrier endothelial cells in vitro JV Georgieva, D Kalicharan, PO Couraud, IA Romero, B Weksler, ... Molecular Therapy 19 (2), 318-325, 2011 | 236 | 2011 |
Smuggling drugs into the brain: an overview of ligands targeting transcytosis for drug delivery across the blood–brain barrier JV Georgieva, D Hoekstra, IS Zuhorn Pharmaceutics 6 (4), 557-583, 2014 | 235 | 2014 |
Gene delivery by cationic lipids: in and out of an endosome D Hoekstra, J Rejman, L Wasungu, F Shi, I Zuhorn Biochemical Society Transactions 35 (1), 68-71, 2007 | 234 | 2007 |
How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances Z ur Rehman, IS Zuhorn, D Hoekstra Journal of Controlled Release 166 (1), 46-56, 2013 | 225 | 2013 |
On the mechanism of cationic amphiphile-mediated transfection. To fuse or not to fuse: is that the question? IS Zuhorn, D Hoekstra The Journal of membrane biology 189, 167-179, 2002 | 198 | 2002 |
Lipoplex formation under equilibrium conditions reveals a three-step mechanism V Oberle, U Bakowsky, IS Zuhorn, D Hoekstra Biophysical journal 79 (3), 1447-1454, 2000 | 173 | 2000 |
Phase behavior of cationic amphiphiles and their mixtures with helper lipid influences lipoplex shape, DNA translocation, and transfection efficiency IS Zuhorn, V Oberle, WH Visser, JBFN Engberts, U Bakowsky, ... Biophysical journal 83 (4), 2096-2108, 2002 | 171 | 2002 |
Solid lipid nanoparticles as nucleic acid delivery system: Properties and molecular mechanisms MB De Jesus, IS Zuhorn Journal of controlled release 201, 1-13, 2015 | 153 | 2015 |
Peptide-mediated blood-brain barrier transport of polymersomes JV Georgieva, RP Brinkhuis, K Stojanov, CAGM Weijers, H Zuilhof, ... | 142 | 2012 |
Interference of serum with lipoplex–cell interaction: modulation of intracellular processing IS Zuhorn, WH Visser, U Bakowsky, JBFN Engberts, D Hoekstra Biochimica et Biophysica Acta (BBA)-Biomembranes 1560 (1-2), 25-36, 2002 | 114 | 2002 |
Size Dependent Biodistribution and SPECT Imaging of 111In-Labeled Polymersomes RP Brinkhuis, K Stojanov, P Laverman, J Eilander, IS Zuhorn, FPJT Rutjes, ... Bioconjugate chemistry 23 (5), 958-965, 2012 | 81 | 2012 |