Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities CM Gay, CA Stewart, EM Park, L Diao, SM Groves, S Heeke, BY Nabet, ... Cancer cell 39 (3), 346-360. e7, 2021 | 554 | 2021 |
STING pathway expression identifies NSCLC with an immune-responsive phenotype CM Della Corte, T Sen, CM Gay, K Ramkumar, L Diao, RJ Cardnell, ... Journal of Thoracic Oncology 15 (5), 777-791, 2020 | 112 | 2020 |
Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2–Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology CA Stewart, CM Gay, K Ramkumar, KR Cargill, RJ Cardnell, MB Nilsson, ... Journal of Thoracic Oncology 16 (11), 1821-1839, 2021 | 96* | 2021 |
Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC PO Gaudreau, MV Negrao, KG Mitchell, A Reuben, EM Corsini, J Li, ... Journal of Thoracic Oncology 16 (1), 127-139, 2021 | 63 | 2021 |
Comutations and KRASG12C Inhibitor Efficacy in Advanced NSCLC MV Negrao, HA Araujo, G Lamberti, AJ Cooper, NS Akhave, T Zhou, ... Cancer discovery 13 (7), 1556-1571, 2023 | 57 | 2023 |
ISA101 and nivolumab for HPV-16+ cancer: updated clinical efficacy and immune correlates of response LG De Sousa, K Rajapakshe, JR Canales, RL Chin, L Feng, Q Wang, ... Journal for immunotherapy of cancer 10 (2), 2022 | 53 | 2022 |
AXL Inhibition Induces DNA Damage and Replication Stress in Non–Small Cell Lung Cancer Cells and Promotes Sensitivity to ATR Inhibitors K Ramkumar, CA Stewart, KR Cargill, CM Della Corte, Q Wang, L Shen, ... Molecular Cancer Research 19 (3), 485-497, 2021 | 37 | 2021 |
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer M Chen, R Chen, Y Jin, J Li, X Hu, J Zhang, J Fujimoto, SM Hubert, ... Nature communications 12 (1), 6655, 2021 | 32 | 2021 |
CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance MB Nilsson, Y Yang, S Heeke, SA Patel, A Poteete, H Udagawa, ... Cancer cell 41 (2), 340-355. e6, 2023 | 31 | 2023 |
MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers O Alhalabi, J Chen, Y Zhang, Y Lu, Q Wang, S Ramachandran, ... Nature communications 13 (1), 1797, 2022 | 31 | 2022 |
Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer KR Cargill, CA Stewart, EM Park, K Ramkumar, CM Gay, RJ Cardnell, ... Cancer & metabolism 9, 1-16, 2021 | 31 | 2021 |
MCT4-dependent lactate secretion suppresses antitumor immunity in LKB1-deficient lung adenocarcinoma Y Qian, A Galan-Cobo, I Guijarro, M Dang, D Molkentine, A Poteete, ... Cancer cell 41 (7), 1363-1380. e7, 2023 | 26 | 2023 |
Dynamic expression of Schlafen 11 (SLFN11) in circulating tumour cells as a liquid biomarker in small cell lung cancer B Zhang, CA Stewart, Q Wang, RJ Cardnell, P Rocha, J Fujimoto, ... British journal of cancer 127 (3), 569-576, 2022 | 13 | 2022 |
Glucuronoxylomannan in the Cryptococcus species capsule as a target for Chimeric Antigen Receptor T-cell therapy TA Da Silva, PJ Hauser, I Bandey, T Laskowski, Q Wang, AM Najjar, ... Cytotherapy 23 (2), 119-130, 2021 | 13 | 2021 |
Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis IS Batth, Q Meng, Q Wang, KE Torres, J Burks, J Wang, R Gorlick, S Li BMC cancer 20, 1-10, 2020 | 10 | 2020 |
Tumor-and circulating-free DNA methylation identifies clinically relevant small cell lung cancer subtypes S Heeke, CM Gay, MR Estecio, H Tran, BB Morris, B Zhang, X Tang, ... Cancer Cell 42 (2), 225-237. e5, 2024 | 9 | 2024 |
Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis Z Chen, IL Ho, M Soeung, EY Yen, J Liu, L Yan, JL Rose, S Srinivasan, ... Nature communications 14 (1), 2194, 2023 | 9 | 2023 |
NBTXR3 improves the efficacy of immunoradiotherapy combining nonfucosylated anti-CTLA4 in an anti-PD1 resistant lung cancer model Y Hu, S Paris, G Bertolet, HB Barsoumian, Q Wang, J Da Silva, NB Patel, ... Frontiers in immunology 13, 1022011, 2022 | 8 | 2022 |
Triple blockade of Ido-1, PD-L1 and MEK as a potential therapeutic strategy in NSCLC CM Della Corte, V Ciaramella, K Ramkumar, G Vicidomini, A Fiorelli, ... Journal of translational medicine 20 (1), 541, 2022 | 5 | 2022 |
Membrane-Anchored and Tumor-Targeted IL12 (attIL12)-PBMC Therapy for Osteosarcoma Q Yang, J Hu, Z Jia, Q Wang, J Wang, LH Dao, W Zhang, S Zhang, X Xia, ... Clinical Cancer Research 28 (17), 3862-3873, 2022 | 5 | 2022 |