Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors A Maresca, C Temperini, H Vu, NB Pham, SA Poulsen, A Scozzafava, ... Journal of the American Chemical Society 131 (8), 3057-3062, 2009 | 550 | 2009 |
Adenosine receptors: new opportunities for future drugs SA Poulsen, RJ Quinn Bioorganic & medicinal chemistry 6 (6), 619-641, 1998 | 429 | 1998 |
Discovery of a new family of carbonic anhydrases in the malaria pathogen Plasmodium falciparum—The η-carbonic anhydrases S Del Prete, D Vullo, GM Fisher, KT Andrews, SA Poulsen, C Capasso, ... Bioorganic & Medicinal Chemistry Letters 24 (18), 4389-4396, 2014 | 354 | 2014 |
Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 298 | 2016 |
Carbonic anhydrase inhibitors: inhibition of isozymes I, II, and IX with triazole-linked O-glycosides of benzene sulfonamides BL Wilkinson, LF Bornaghi, TA Houston, A Innocenti, D Vullo, CT Supuran, ... Journal of medicinal chemistry 50 (7), 1651-1657, 2007 | 242 | 2007 |
A novel class of carbonic anhydrase inhibitors: glycoconjugate benzene sulfonamides prepared by “click-tailing” BL Wilkinson, LF Bornaghi, TA Houston, A Innocenti, CT Supuran, ... Journal of medicinal chemistry 49 (22), 6539-6548, 2006 | 210 | 2006 |
Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function GRL Cousins, SA Poulsen, JKM Sanders Current Opinion in Chemical Biology 4 (3), 270-279, 2000 | 203 | 2000 |
Synthetic utility of glycosyl triazoles in carbohydrate chemistry BL Wilkinson, LF Bornaghi, SA Poulsen, TA Houston Tetrahedron 62 (34), 8115-8125, 2006 | 147 | 2006 |
Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors JC Morris, J Chiche, C Grellier, M Lopez, LF Bornaghi, A Maresca, ... Journal of medicinal chemistry 54 (19), 6905-6918, 2011 | 137 | 2011 |
Screening the medicines for malaria venture pathogen box across multiple pathogens reclassifies starting points for open-source drug discovery S Duffy, ML Sykes, AJ Jones, TB Shelper, M Simpson, R Lang, ... Antimicrobial agents and chemotherapy 61 (9), 10.1128/aac. 00379-17, 2017 | 127 | 2017 |
Therapeutic applications of glycosidic carbonic anhydrase inhibitors JY Winum, SA Poulsen, CT Supuran Medicinal research reviews 29 (3), 419-435, 2009 | 126 | 2009 |
Natural product coumarins that inhibit human carbonic anhydrases RA Davis, D Vullo, A Maresca, CT Supuran, SA Poulsen Bioorganic & medicinal chemistry 21 (6), 1539-1543, 2013 | 118 | 2013 |
Natural product-based phenols as novel probes for mycobacterial and fungal carbonic anhydrases RA Davis, A Hofmann, A Osman, RA Hall, FA Mühlschlegel, D Vullo, ... Journal of Medicinal Chemistry 54 (6), 1682-1692, 2011 | 114 | 2011 |
Cyclic secondary sulfonamides: unusually good inhibitors of cancer-related carbonic anhydrase enzymes J Moeker, TS Peat, LF Bornaghi, D Vullo, CT Supuran, SA Poulsen Journal of medicinal chemistry 57 (8), 3522-3531, 2014 | 107 | 2014 |
Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII AJ Salmon, ML Williams, QK Wu, J Morizzi, D Gregg, SA Charman, ... Journal of medicinal chemistry 55 (11), 5506-5517, 2012 | 106 | 2012 |
Microwave-accelerated Fischer glycosylation LF Bornaghi, SA Poulsen Tetrahedron Letters 46 (20), 3485-3488, 2005 | 103 | 2005 |
Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site RP Tanpure, B Ren, TS Peat, LF Bornaghi, D Vullo, CT Supuran, ... Journal of medicinal chemistry 58 (3), 1494-1501, 2015 | 102 | 2015 |
Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides BL Wilkinson, A Innocenti, D Vullo, CT Supuran, SA Poulsen Journal of medicinal chemistry 51 (6), 1945-1953, 2008 | 97 | 2008 |
Direct screening of a dynamic combinatorial library using mass spectrometry SA Poulsen Journal of the American Society for Mass Spectrometry 17 (8), 1074-1080, 2006 | 92 | 2006 |
Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product … RA Davis, A Innocenti, SA Poulsen, CT Supuran Bioorganic & medicinal chemistry 18 (1), 14-18, 2010 | 84 | 2010 |