Intestinal solute carriers: an overview of trends and strategies for improving oral drug absorption B Steffansen, CU Nielsen, B Brodin, AH Eriksson, R Andersen, S Frokjaer European journal of pharmaceutical sciences 21 (1), 3-16, 2004 | 219 | 2004 |
Transport of peptidomimetic drugs by the intestinal di/tri‐peptide transporter, PepT1 B Brodin, CU Nielsen, B Steffansen, S Frøkjær Pharmacology & toxicology 90 (6), 285-296, 2002 | 157 | 2002 |
Epidermal growth factor inhibits glycylsarcosine transport and hPepT1 expression in a human intestinal cell line CU Nielsen, J Amstrup, B Steffansen, S Frokjaer, B Brodin American Journal of Physiology-Gastrointestinal and Liver Physiology 281 (1 …, 2001 | 124 | 2001 |
Genetic variants of the human H+/dipeptide transporter PEPT2: analysis of haplotype functions J Pinsonneault, CU Nielsen, W Sadée Journal of Pharmacology and Experimental Therapeutics 311 (3), 1088-1096, 2004 | 104 | 2004 |
Passive diffusion of drug substances: the concepts of flux and permeability B Brodin, B Steffansen, CU Nielsen Molecular Biopharmaceutics, 135-152, 2010 | 100* | 2010 |
In vitro evidence for the brain glutamate efflux hypothesis: Brain endothelial cells cocultured with astrocytes display a polarized brain‐to‐blood transport of glutamate HC Helms, R Madelung, HS Waagepetersen, CU Nielsen, B Brodin Glia 60 (6), 882-893, 2012 | 92 | 2012 |
Dipeptide model prodrugs for the intestinal oligopeptide transporter. Affinity for and transport via hPepT1 in the human intestinal Caco-2 cell line CU Nielsen, R Andersen, B Brodin, S Frokjaer, ME Taub, B Steffansen Journal of Controlled Release 76 (1-2), 129-138, 2001 | 90 | 2001 |
Di/tri-peptide transporters as drug delivery targets: regulation of transport under physiological and patho-physiological conditions CU Nielsen, B Brodin Current drug targets 4 (5), 373-388, 2003 | 85 | 2003 |
Paracellular tightness and claudin-5 expression is increased in the BCEC/astrocyte blood–brain barrier model by increasing media buffer capacity during growth HC Helms, HS Waagepetersen, CU Nielsen, B Brodin The AAPS journal 12, 759-770, 2010 | 79 | 2010 |
Human proton/oligopeptide transporter (POT) genes: identification of putative human genes using bioinformatics CW Botka, TW Wittig, RC Graul, CU Nielsen, W Sadée, K Higaki, ... AAPS PharmSci 2, 76-97, 2000 | 76 | 2000 |
Model prodrugs designed for the intestinal peptide transporter. A synthetic approach for coupling of hydroxy-containing compounds to dipeptides GM Friedrichsen, CU Nielsen, B Steffansen, M Begtrup European journal of pharmaceutical sciences 14 (1), 13-19, 2001 | 62 | 2001 |
Human peptide transporters: therapeutic applications CU Nielsen, B Brodin, FS Jørgensen, S Frokjaer, B Steffansen Expert Opinion on Therapeutic Patents 12 (9), 1329-1350, 2002 | 59 | 2002 |
An Electrically Tight In Vitro Blood–Brain Barrier Model Displays Net Brain-to-Blood Efflux of Substrates for the ABC Transporters, P-gp, Bcrp and Mrp-1 HC Helms, M Hersom, LB Kuhlmann, L Badolo, CU Nielsen, B Brodin The AAPS journal 16, 1046-1055, 2014 | 58 | 2014 |
Genetic variants of the human dipeptide transporter PEPT1 P Anderle, CU Nielsen, J Pinsonneault, PL Krog, B Brodin, W Sadée Journal of Pharmacology and Experimental Therapeutics 316 (2), 636-646, 2006 | 58 | 2006 |
δ‐Aminolevulinic acid is a substrate for the amino acid transporter SLC36A1 (hPAT1) S Frølund, OC Marquez, M Larsen, B Brodin, CU Nielsen British journal of pharmacology 159 (6), 1339-1353, 2010 | 51 | 2010 |
Nonionic surfactants modulate the transport activity of ATP-binding cassette (ABC) transporters and solute carriers (SLC): Relevance to oral drug absorption AAA Al-Ali, RB Nielsen, B Steffansen, R Holm, CU Nielsen International journal of pharmaceutics 566, 410-433, 2019 | 50 | 2019 |
Epidermal growth factor and insulin short‐term increase hPepT1‐mediated glycylsarcosine uptake in Caco‐2 cells CU Nielsen, J Amstrup, R Nielsen, B Steffansen, S Frokjaer, B Brodin Acta physiologica scandinavica 178 (2), 139-148, 2003 | 50 | 2003 |
Calu-3 cells grown under AIC and LCC conditions: implications for dipeptide uptake and transepithelial transport of substances A Stentebjerg-Andersen, IV Notlevsen, B Brodin, CU Nielsen European journal of pharmaceutics and biopharmaceutics 78 (1), 19-26, 2011 | 49 | 2011 |
Delivery aspects of small peptides and substrates for peptide transporters B Steffansen, CU Nielsen, S Frokjaer European journal of pharmaceutics and biopharmaceutics 60 (2), 241-245, 2005 | 49 | 2005 |
Phe-Gly dipeptidomimetics designed for the di-/tripeptide transporters PEPT1 and PEPT2: synthesis and biological investigations J Våbenø, T Lejon, CU Nielsen, B Steffansen, W Chen, H Ouyang, ... Journal of medicinal chemistry 47 (4), 1060-1069, 2004 | 49 | 2004 |